Glutaminase 1 plays critical roles in myelodysplastic syndrome and acute myeloid leukemia cells [0.03%]
谷氨酰胺酶1在骨髓增生异常综合征和急性髓系白血病细胞中起关键作用
Seiichi Okabe,Mitsuru Moriyama,Yuya Arai et al.
Seiichi Okabe et al.
Background: Myelodysplastic syndrome (MDS) features bone marrow failure and a heightened risk of evolving into acute myeloid leukemia (AML), increasing with age and reducing overall survival. Given the unfavorable outcome...
HNRNPA2B1 induces cell proliferation and acts as biomarker in breast cancer [0.03%]
HNRNPA2B1诱导细胞增殖并作为乳腺癌的生物标志物
Yi Yang,Yi Zhang,Tongbao Feng et al.
Yi Yang et al.
Background: Numerous studies have shown that m6A plays an important regulatory role in the development of tumors. HNRNPA2B1, one of the m6A RNA methylation reading proteins, has been proven to be elevated in human cancers...
Comparative analysis of features and classification techniques in breast cancer detection for Biglycan biomarker images [0.03%]
用于大lys标志物图像的乳腺癌检测特征和分类技术的比较分析
Jumana Ma&#x;touq,Nasim Alnuman
Jumana Ma&#x;touq
Background: Breast cancer (BC) is considered the world's most prevalent cancer. Early diagnosis of BC enables patients to receive better care and treatment, hence lowering patient mortality rates. Breast lesion identifica...
Hypermethylation of the BRCA2 gene promoter and its co-hypermethylation with the BRCA1 gene promoter in patients with breast cancer [0.03%]
乳腺癌患者中BRCA2基因启动区的高甲基化及其与BRCA1基因启动区联合高甲基化的研究
Liliia Fishchuk,Zoia Rossokha,Olga Lobanova et al.
Liliia Fishchuk et al.
Background: The BRCA2 gene is an important tumour suppressor in breast cancer, and alterations in BRCA2 may lead to cancer progression. The aim of the study was to investigate the association of hypermethylation of the BR...
Differentially expressed microRNA in prognosis of gastric cancer with Lauren classification [0.03%]
拉奥分类胃癌预后的差异表达微小核糖核酸
Wenjiao Chen,Qin Guo,Huo Zhang et al.
Wenjiao Chen et al.
Background: Gastric cancer (GC) is one of the most common tumors. There were several classifications of GC recently. The value of Lauren classification in evaluating the prognosis after radical gastrectomy was still uncle...
A computed tomography-based score indicative of lung cancer aggression (SILA) predicts lung adenocarcinomas with low malignant potential or vascular invasion [0.03%]
基于CT的肺癌侵袭性评分（SILA）可预测低恶性肺腺癌或血管侵犯指标
Dylan Steiner,Ju Ae Park,Sarah Singh et al.
Dylan Steiner et al.
Background: Histologic grading of lung adenocarcinoma (LUAD) is predictive of outcome but is only possible after surgical resection. A radiomic biomarker predictive of grade has the potential to improve preoperative manag...
Pulmonary adenocarcinoma of low malignant potential defines indolent NSCLC associated with overdiagnosis in the national lung screening trial [0.03%]
国家肺癌筛查试验中低恶性潜能肺腺癌定义为与过度诊断相关的惰性非小细胞肺癌
Eric J Burks,Travis B Sullivan,Kimberly M Rieger-Christ
Eric J Burks
Background: The national lung screening trial (NLST) demonstrated a reduction in lung cancer mortality with lowdose CT (LDCT) compared to chest x-ray (CXR) screening. Overdiagnosis was high (79%) among bronchoalveolar car...
Identification of candidate biomarkers and prognostic analysis of recurrence in colorectal cancer [0.03%]
结直肠癌复发相关候选标志物的识别及预后分析
Rui Xu,Huayun Feng,Haojie Liang et al.
Rui Xu et al.
Colorectal cancer (CRC) is one of the most common digestive tract malignant tumors, which has a high mortality rate especially for patients with CRC recurrence. However, the pathological mechanism of recurrence of CRC is unclear. In this st...
Rho GTPase-activating protein 4 is upregulated in Kidney Renal Clear Cell Carcinoma and associated with poor prognosis and immune infiltration [0.03%]
Rho GTP酶活化蛋白4在肾透明细胞癌中高表达并提示不良预后和免疫浸润
Xuesong Xiao,Xiaofei Lv,Tianyu Lin et al.
Xuesong Xiao et al.
Background: Kidney Renal Clear Cell Carcinoma (KIRC) is a malignant tumor that seriously threatens human health. Rho GTPase-activating protein 4 (ARHGAP4) plays an important role in the occurrence and development of tumor...