Metal Dependent Glycosidases of Sea Cucumber Eupentacta Fraudatrix and their Properties [0.03%]
海 cucumber Eupentacta fraudatrix 的金属依赖性糖基水解酶及其性质研究
Svetlana E Soboleva,Nadejda A Maltseva,Irina A Kostrikina et al.
Svetlana E Soboleva et al.
Sea cucumbers Eupentacta fraudatrix can completely regenerate their organs within one month after evisceration. The regeneration process involves complex structural changes including restructuring of the intracellular matrix. The connective...
Methylglyoxal-Induced Modification of Hen Egg White Lysozyme: Detection of Advanced Glycation End Products by High Resolution Mass Spectrometry [0.03%]
甲醛修饰鸡卵清 lysozyme 的研究及其晚期糖基化终末产物的高通量质谱分析方法
Sauradipta Banerjee
Sauradipta Banerjee
Methylglyoxal is a highly reactive α-oxoaldehyde that forms advanced glycation end products (AGEs) on reaction with proteins. Here, we have studied the effect of methylglyoxal on hen egg white lysozyme (HEWL), after incubation for differen...
Molecular, Structural and Functional Characterization of Antheraea mylitta Expressed Cocoonase: An Integrative Approach [0.03%]
家蚕蛾Antheraea mylitta表达的茧壳酶的分子、结构和功能特征：一种综合方法
Nishi Prakash Tiwari,Jay Prakash Pandey,Dev Mani Pandey
Nishi Prakash Tiwari
Cocoonase, a vital naturally secreted protease, enables moth emergence by specifically degumming sericin from cocoons, leaving fibroin intact. This unique characteristic makes it highly promising for protein-based silk degumming. Present st...
Functional and Structural Insights into Phenoloxidase from Hermetia illucens: A Combined Biochemical and Computational Approach [0.03%]
赫metis illucens苯酚氧化酶的功能和结构洞察：生物化学和计算方法的结合研究
K Sruthi,B N Marieshwari,S Bhuvaragavan et al.
K Sruthi et al.
The enzyme phenoloxidase (PO) is an essential component in the immune system of insects, which is responsible for the rapid activation and encapsulation of microbial pathogens. This study focuses on the in vitro and in silico investigation ...
Combining Cryo-EM with Computational Approaches To Revolutionize Structural Biology [0.03%]
结合电子低温显微镜和计算方法以变革结构生物学
Han-Ul Kim,Mi Young An,Young Kwan Kim et al.
Han-Ul Kim et al.
The development of cryo-electron microscopy (cryo-EM) has led to significant advancements in the field of structural biology. Specifically, improvements in both hardware and software for cryo-EM have not only addressed previously perceived ...
Proteomic Analysis of Serum Samples in Ovulatory Polycystic Ovary Syndrome and Construction of a Protein Interaction Pathway [0.03%]
黄体期多囊卵巢综合征的血清蛋白质组学分析及蛋白互作通路构建
Ahmad Fazilat,Keivan Majidzadeh-A,Kambiz Gilany et al.
Ahmad Fazilat et al.
As a heterogeneous multifactorial disorder, PCOS still has a misty etiology. Its underlying pathophysiological causes can be further elucidated by proteomic analyses and molecular network analysis to understand the interaction pathways invo...
Unlocking the Therapeutic Potential of Cyclic Peptide-Based Nanocarriers for Enhanced Colon Cancer Treatment [0.03%]
基于环肽的纳米载体用于增强结肠癌治疗的潜在机制研究
Vedhapriya Souresh,M Srikayalsamyukktha,M Harini et al.
Vedhapriya Souresh et al.
Cyclic peptides have emerged as therapeutic agents for colon cancer due to their structural stability, enhanced bioavailability, and high target specificity. Natural cyclic peptides derived from plant, marine, and microbial sources exhibit ...
Mechanistic In-Silico Insights into the Anti-quorum Sensing Potential of Coumaric Acid and Syringic Acid in Serratia marcescens with Invitro Analysis [0.03%]
黄酮酸和丁香酸抑制产红色色素肠杆菌细胞间通讯的机制及离体分析
Pooja Pandey,Bipin R Shekhar,Dhanjit K Das et al.
Pooja Pandey et al.
Antibiotic resistance presents a major global health threat, especially with ESKAPE pathogens like Serratia marcescens, which exhibit resistance to all known antibiotics. Quorum sensing (QS) is key to its virulence and resistance, emphasizi...
Unravelling the Phosphorylation Landscape of Anthrax Toxin Receptor 1: Mechanisms and Functional Insights Through Phosphoproteomic Data Integration [0.03%]
整合磷蛋白组数据解码炭疽毒素受体1的磷酸化图谱：机制和功能见解
Ayadathil Sujina,Amal Fahma,Suhail Subair et al.
Ayadathil Sujina et al.
Anthrax Toxin Receptor 1 (ANTXR1) is a transmembrane protein involved in various biological processes, including angiogenesis, cell adhesion, and migration. As a receptor for Bacillus anthracis toxins and the oncolytic Seneca Valley virus, ...
Exploring Wheat Leaf Urease for a Sustainable Approach: Purification, Kinetics, and Thermal Stability Characterization [0.03%]
可持续探索小麦叶脲酶的方法：纯化、动力学和热稳定性特征研究
Surbhi Sahewalla,Sonam Sihag,Anil Duhan et al.
Surbhi Sahewalla et al.
The urease enzyme has an inevitable application in cereal crops, particularly in response to foliar urea application. A holistic and novel approach was employed in the present work with the aim to purify and characterize the wheat leaf urea...