Heterologous expression of stress-responsive DUF538 domain containing protein and its morpho-biochemical consequences [0.03%]
异源表达逆境响应DUF538结构域蛋白及其形态生化效应
Ashraf Gholizadeh
Ashraf Gholizadeh
As a usual response, plants induce/activate various proteins which are thought to be involved in defense mechanisms against the biotic and abiotic stresses they may be confronted with. The novel DUF538 domain containing proteins with unknow...
Bactericidal activity identified in 2S Albumin from sesame seeds and in silico studies of structure-function relations [0.03%]
芝麻籽2S清蛋白具抗菌活性及结构功能关系的理论研究
Simone Maria-Neto,Rodrigo V Honorato,Fábio T Costa et al.
Simone Maria-Neto et al.
Pathogenic bacteria constitute an important cause of hospital-acquired infections. However, the misuse of available bactericidal agents has led to the appearance of antibiotic-resistant strains. Thus, efforts to seek new antimicrobials with...
Identification of a lysine residue important for the catalytic activity of yeast farnesyl diphosphate synthase [0.03%]
鉴定出一个对于酵母法尼基二磷酸合成酶催化活性非常重要的赖氨酸残基
Marc J C Fischer,Sophie Meyer,Patricia Claudel et al.
Marc J C Fischer et al.
The Saccharomyces cerevisiae ERG20 gene (encoding farnesyl diphosphate synthase) has been subjected to a set of mutations at the catalytic site, at position K254 to determine the in vivo impact. The mutated strains have been shown to exhibi...
Thermal denaturation of β-glucosidase B from Paenibacillus polymyxa proceeds through a Lumry-Eyring mechanism [0.03%]
多黏类芽孢杆菌β-葡萄糖苷酶B的热变性通过Lumry-Eyring机制进行
Menandro Camarillo-Cadena,Georgina Garza-Ramos,Mariana Peimbert et al.
Menandro Camarillo-Cadena et al.
β-glucosidase B (BglB), 1,4-β-D: -glucanohydrolase, is an enzyme with various technological applications for which some thermostable mutants have been obtained. Because BglB denatures irreversibly with heating, the stabilities of these mu...
Structural insights on two hypothetical secretion chaperones from Xanthomonas axonopodis pv. citri [0.03%]
木瓜黄单胞菌假定分泌伴侣蛋白的结构研究
Juliana Fattori,Alessandra Prando,Leandro H P Assis et al.
Juliana Fattori et al.
Several Gram-negative bacterial pathogens have developed type III secretion systems (T3SSs) to deliver virulence proteins directly into eukaryotic cells in a process essential for many diseases. The type III secretion processes require cust...
Expression and purification of a natural N-terminal pre-ligand assembly domain of tumor necrosis factor receptor 1 (TNFR1 PLAD) and preliminary activity determination [0.03%]
肿瘤坏死因子受体1PLAD的原核表达纯化及初步活性测定
Jin Cao,Fang Meng,Xiangdong Gao et al.
Jin Cao et al.
A domain at the NH(2) terminal (N-terminal) of tumor necrosis factor receptor (TNFR) termed the pre-ligand binding assembly domain (PLAD). The finding that PLAD can mediate a selective TNFR assembly in previously researches provides a novel...
Proteomic analyses of gastric cancer cells treated with vesicular stomatitis virus matrix protein [0.03%]
Venezuelan马蹄病病毒基质蛋白处理的胃癌细胞的蛋白质组分析
Dequan Zeng,Tao Zhang,Shengtao Zhou et al.
Dequan Zeng et al.
Gastric cancer constitutes the second leading cause of mortality worldwide and the fourth most common cancer. While chemotherapy remains the primary treatment for both resectable and advanced gastric cancer, most gastric cancers are natural...
Classification of bacteria based on the biases of terminal amino acid residues [0.03%]
基于末端氨基酸残基偏差的细菌分类
Michio Asada,Hideki Hirakawa,Satoru Kuhara
Michio Asada
The frequencies of amino acid residues are known to be biased at both terminal regions of amino acid sequences deduced from bacterial genomic DNA. To investigate whether or not the features of biases of amino acid residues at the terminal r...
Effect of homocysteine thiolactone on structure and aggregation propensity of bovine pancreatic insulin [0.03%]
同型半胱氨酸内酯对牛胰岛素结构及聚集特性的影响
Shima Jalili,Reza Yousefi,Mohammad-Mehdi Papari et al.
Shima Jalili et al.
Homocysteine thiolactone (HCTL) is a cyclic thioester of homocysteine, showing high reactivity toward lysine residues of proteins. In the present study the structural properties and aggregation propensity of bovine pancreatic insulin were s...
Mixed-type inhibition of tyrosinase from Agaricus bisporus by terephthalic acid: computational simulations and kinetics [0.03%]
对苯二甲酸抑制银耳漆酶的混合型抑制作用：动力学与计算模拟研究
Shang-Jun Yin,Yue-Xiu Si,Yong-Fu Chen et al.
Shang-Jun Yin et al.
Tyrosinase inhibition studies are needed due to the agricultural and medicinal applications. For probing effective inhibitors of tyrosinase, a combination of computational prediction and enzymatic assay via kinetics were important. We predi...