An Insight into Different Experimental Models used for Hepatoprotective Studies: A Review [0.03%]
肝保护研究中不同实验模型的见解:一篇综述
Sucharita Babu,Santosh K Ranajit,Gurudutta Pattnaik et al.
Sucharita Babu et al.
Numerous factors, including exposure to harmful substances, drinking too much alcohol, contracting certain hepatitis serotypes, and using specific medicines, contribute to the development of liver illnesses. Lipid peroxidation and other for...
Molecular Modeling of Brassicaceae Derivatives for Inhibiting Lipoxygenases: A Promising Therapeutic Strategy [0.03%]
分子模拟布拉基科植物衍生化合物抑制环氧合酶:一种有前景的治疗策略
Wassila Soufi,Hocine Allali,Faïza Boukli Hacene et al.
Wassila Soufi et al.
Introduction: Inflammation plays a crucial role in the body's defense mechanisms, but uncontrolled inflammation can lead to chronic and pathological conditions. This study aimed to identify natural compounds as potential ...
Novel Approaches for the Enhancement of Bioavailability of Drugs: An Updated Review [0.03%]
改善药物生物利用度的新方法:综述更新
Jyoshna Rani Dash,Gurudutta Pattnaik,Himansu Bhusan Samal et al.
Jyoshna Rani Dash et al.
In medicine, bioavailability is the percentage of a drug that enters the bloodstream and can be used to treat a patient. It has proven challenging throughout time to develop techniques that allow oral administration of most drugs, regardles...
The Genus Paeonia: A Review of the Targeted Signaling Pathways and Underlying Mechanisms of Pharmacological and Clinical Properties [0.03%]
牡丹属的研究进展:药理及临床作用的靶信号途径及其机制综述
Atefeh Jalali,Fereshteh Jafari,Shima Behnamrad et al.
Atefeh Jalali et al.
Introduction: The Paeoniaceae family contains only the Paeonia genus and is considered the major group of flowering plants. Several traditional and pharmacological applications of Paeoniaceae herbs have been described. Th...
Hepatoprotective Potential of Murraya koenigii (Curry Leaves) against Xenobiotics, Heavy Metals, and Hepatotoxic Agents: A Comprehensive Review [0.03%]
圣洁木( curry leaves)对抗外来物、重金属和肝毒性物质的肝脏保护潜力:全面综述
Rohit Gangawat,Ronit Parashar,Ritu Kamal Yadav
Rohit Gangawat
Liver disease, responsible for two million annual deaths, causes Chronic Liver Disease (CLD) and cirrhosis, causing roughly a million deaths yearly. Treatment options for liver injury induced by hepatotoxicity vary, including medication (N-...
Synthesis, Molecular Docking, and Antimicrobial Evaluation of 2-(Substituted Amino)-N-(6-Substituted-1,3-Benzothiazol-2yl) Acetamide [0.03%]
2-(取代胺)-N-(6-取代-1,3-苯并噻唑-2-基)乙酰胺的合成、分子对接及抗菌活性评价
Smita Pawar,Amol Kale,Priya Zori et al.
Smita Pawar et al.
Background: The development of antimicrobial agents is crucial for several reasons, primarily to combat infectious diseases and to address the growing threat of antimicrobial resistance. The need for the contin-ued develo...
Rushika Joshi,Devang Sheth,Jayesh Beladiya et al.
Rushika Joshi et al.
In underdeveloped nations, tuberculosis (TB) continues to be a major source of morbidity and mortality. The currently available vaccine against tuberculosis in endemic areas is mainly ineffective, which triggers the need for a clinically ef...
Ivan Santos,M Beatriz P P Oliveira,Ana Casas et al.
Ivan Santos et al.
Cannabinoids are compounds with increasing scientific interest, particularly due to their interaction with the endocannabinoid system via CBR1 and CBR2 receptors. They can interfere with appetite, pain, and sleep or develop mood changes of ...
Bharat V Dhokchawle,Punit Mishra,Renny J Daniel
Bharat V Dhokchawle
One lucrative method for overcoming challenges in drug discovery or for enhancing undesirable properties of already-approved medications is prodrug design. The goal of this review is to present researchers with a profile of naturally occurr...
Shital M Patil,Indrani Mahadik,Shashikant V Bhandari et al.
Shital M Patil et al.
Background: Inhibiting receptor-tyrosine-kinase (RTK) signalling pathways has emerged as a key focus of novel cancer therapy development. Vascular endothelial growth factor receptor (VEGFR) is a member of the RTK family a...