A Systematic Review on Natural Products, Nanotechnology and their Recent Updates Towards Management of CFA-induced Rheumatoid Arthritis [0.03%]
天然产物和纳米技术在治疗类风湿关节炎方面的系统评价及最新研究进展
Zulfa Nooreen,Ankita Wal,Awani Kumar Rai et al.
Zulfa Nooreen et al.
Introduction: The inflamed, symmetrical, persistent autoimmune condition, rheu-matoid arthritis, starts small and gradually spreads to bigger joints. It may damage joints and internal organs resulting in permanent impairment. The treatment ...
Quantitative Structure-Activity-Amino Acid Relationship of Benzodiazepines and Thienodiazepine via Molecular Docking Simulation [0.03%]
基于分子对接模拟的苯二氮卓和噻嗪类药物构效关系及定量构氨关系研究
Ankita Sharma,Shweta Verma,Sisir Nandi
Ankita Sharma
Introduction: Benzodiazepine (BZD) and thienodiazepine (TND) congeners are highly effective in managing central nervous system (CNS) disorders such as anxiety, insomnia, depression, and epilepsy. However, this class of co...
Meta-Modeling with Drug Discovery Stack Regressor for Drug Discovery: An Explainable AI Perspective [0.03%]
一种用于药物发现的可解释AI的药物发现栈回归元建模方法
Spoorthi J S,Vijayalakshmi M,Sasithradevi A et al.
Spoorthi J S et al.
Introduction: Drug discovery faces persistent challenges, including the need to handle heterogeneous datasets, extended timelines, and difficulties in accurately predicting drug-target interactions. These issues hinder th...
Reetu Chauhan,Shikha Sharma,Jagdish K Sahu et al.
Reetu Chauhan et al.
Medicinal plants are a rich source of therapeutic agents. Tuberculosis (TB) is a highly infectious disease causing significant morbidity and mortality, primarily due to its causative agent, Mycobacterium tuberculosis. The incidence of TB is...
AI-Powered Drug Discovery: A Review of Machine Learning Applications in Carcinoma Diagnosis and Treatment [0.03%]
人工智能驱动的药物发现：机器学习在癌瘤诊断和治疗应用综述
Rakesh Devidas Amrutkar,Anket Chhotu Pawar,Krishna Santosh Jagtap et al.
Rakesh Devidas Amrutkar et al.
AI comprises well-established technology for learning and identifying novel features, such as machine learning. The present article first discusses an overview of drug research, design, and development. We have also entrusted collaborations...
Unraveling Vitiligo: A Multifactorial, Autoimmune Disease - An Insight into its Pathophysiology and Power of Herbal Healing [0.03%]
解密白癜风：一种多因素自身免疫性疾病及其病理生理学和草药治疗的力量
Nikita -,Pravin Kumar,Mahendra Singh Ashawat et al.
Nikita - et al.
Vitiligo, also known as leukoderma, is a chronic autoimmune skin disorder characterized by the progressive loss of melanocytes, leading to depigmented patches on the skin. While it is not life-threatening, the visible nature of the conditio...
A Comprehensive Review on Exploring the Antidiabetic Potential of Naringenin: A Natural Therapeutic Agent [0.03%]
柚皮素抗糖尿病潜力的研究进展：一种天然治疗剂
Bristi Saikia,Rupa Sengupta
Bristi Saikia
Introduction: Naringenin, a key flavonoid abundantly found in citrus fruits, has garnered attention for its wide-ranging pharmacological properties. This review comprehensively examines naringenin, encompassing its source...
Analyze the Sombor Index of Molecular Graphs Representing Antibiotic Drugs Using the ℳ Polynomial [0.03%]
利用ℳ多项式分析代表抗生素药物的分子图的Sombor指数
J Senbagamalar,M S Ramani,Venkata Shivakumar Remella
J Senbagamalar
Introduction: Today's world is grappling with numerous infectious diseases and pandemics caused by bacteria, viruses, fungi, or parasites, which are affecting people at an alarming rate. Molecular topology, a field that s...
In Silico Identification of Endemic Plant-Derived Phytocompounds Targeting H5N1 Influenza Proteins via Molecular Docking and ADME Profiling [0.03%]
基于分子对接和ADME特征筛选的植物来源的抗H5N1流感病毒药用化合物虚拟筛选模型研究
Tarik Corbo,Abdurahim Kalajdzic,Naris Pojskic et al.
Tarik Corbo et al.
Introduction: This study investigates the molecular docking of 306 phytochemicals from Iris, Daphne, and Chrysosplenium species against three key proteins of the H5N1 influenza virus: neuraminidase, polymerase, and hemagg...
Bioactive Furan Derivatives from Streptomyces sp. VITGV100: Insights from in silico Docking and ADMET Profiling [0.03%]
来源于链霉菌VITGV100的生物活性呋喃衍生物：基于计算机对接和ADMET评价的见解
Madhuri Mukindrao Moon,John Godwin Christopher
Madhuri Mukindrao Moon
Introduction: Streptomyces species have complex genomes, including various biosynthetic gene clusters, frequently responsible for producing antibacterial and bioactive secondary metabolites under certain environmental con...