Computational Screening of Novel Nitroimidazole Candidates: Targeting Key Enzymes of Oral Anaerobes for Anti-Parasitic Potential [0.03%]
新型硝基咪唑候选药物的计算筛选：针对口腔厌氧菌的关键酶，开发抗寄生虫潜力药物
Touhami Lanez,Maroua Lanez,Riad Lanez et al.
Touhami Lanez et al.
Background: The study focuses on evaluating the parasitic potential of novel metronidazole analogs using computational methods. Specifically, it aims to target key enzymes of oral anaerobes, including UDP-N-acetylglucosam...
Preliminary Characterization of the Vasorelaxant Effect of Thymus atlanticus (Ball) Roussine Using Optical Methods [0.03%]
光学方法初步评价Thymus atlanticus(Ball)Roussine的血管松弛作用
Hamza Elbouny,Nabil Bouchebchoub,Brahim Ouahzizi et al.
Hamza Elbouny et al.
Background: Thymus atlanticus (Ball) Roussine is a Moroccan endemic thyme species that is traditionally used as an aromatic and medicinal plant. Several studies have demonstrated its pharmacological significance and thera...
AI in Clinical Trials and Drug Development: Challenges and Potential Advancements [0.03%]
人工智能在临床试验和药物开发中的挑战与潜在进展
Divyanshi Gupta,Pranay Wal,Ankita Wal et al.
Divyanshi Gupta et al.
Artificial intelligence (AI) is one of the fastest-growing fields in various industries, including engineering, architecture, medical and clinical research, aerospace, and others. AI, which is a combination of machine learning (ML), deep le...
An Update on Clinically Evaluated Medicinal Plants for Psoriasis Management [0.03%]
用于银屑病管理的临床评价药物植物的更新报告
Ramin Ansari,Mahkameh Moradi Mehrabadi,Mahnaz Sadat Hosseini et al.
Ramin Ansari et al.
Psoriasis is a prevalent inflammatory disease affecting almost 0.5-5 % of the world population. Multiple treatment approaches have been developed to manage psoriasis so far. Although concerns exist in the long-term usage of conventional and...
In Vitro Antibacterial Activity of Adiantum capillus Veneris Extraction with Methanol, Chloroform, and Ether Solvents against Methicillin-resistant Staphylococcus aureus [0.03%]
甲醇、氯仿和醚溶剂提取的肾蕨活性成分对耐甲氧西林金黄色葡萄球菌的体外抗菌活性研究
Mahdiyeh Ebrahimzadeh,Solmaz Rahbari,Reza Hosseini Doust et al.
Mahdiyeh Ebrahimzadeh et al.
Background: The increasing problem of multi-drug resistant (MDR) pathogens is a worldwide concern, especially in the pharmaceutical industry. At the same time, medicinal plants have renewed interest because of their wide ...
Potential Role of Benzoic Acid and its Synthetic Derivatives to Alleviate Cancer: An Up-to-Date Review [0.03%]
苯甲酸及其合成衍生物在缓解癌症方面的潜在作用：最新综述
Arvind Kumar,Kamal Yt,Arun K Mishra et al.
Arvind Kumar et al.
Unregulated cell division is one of the main causes of cancer. These cancerous cells negatively impact nearby healthy cells. Cancer can occur anywhere in the body. Normal cell division occurs when cells grow, reproduce, and divide as the bo...
Liquisolid Technique for Solubility Enhancement of Poorly Soluble Drug - A Brief Review [0.03%]
液体制剂改善药物溶出度的研究进展综述
Amaresh Prusty,Bikash Ranajn Jena,Vivek Barik et al.
Amaresh Prusty et al.
Most of the newly discovered drug candidates are lipophilic and poorly water-soluble, making it a significant challenge for the pharmaceutical industry to formulate suitable drug delivery systems. This review gives insight into an overview ...
In silico Profiling and Pharmacokinetic Modelling of Olivetol: Evaluating its Potential as a Therapeutic Agent for Diabetic Wound Healing [0.03%]
橄榄酚的在线分析及药代动力学建模：评估其作为糖尿病伤口愈合治疗药物的潜力
Nirenjen Shanmugasundaram,Narayanan Jaishankar
Nirenjen Shanmugasundaram
Background: Diabetic wound healing poses a significant challenge due to the intricate disruptions in cellular and molecular processes induced by hyperglycaemia, leading to delayed or impaired tissue repair. Computational ...
Bridging the Gap: Quality by Design as a Catalyst for Enhanced Quality Management Systems in Biopharmaceutical Manufacturing [0.03%]
质量源于设计在生物制药制造中的作用：作为增强质量管理系统的催化剂桥梁
Shivang Saxena,Shubhi Saxena,Diksha et al.
Shivang Saxena et al.
The document emphasizes the importance of addressing key issues in Quality Management Systems (QMS) to stay competitive and provide high-quality goods and services in a dynamic market. It highlights the need to adopt novel quality managemen...
A Comprehensive Investigation: Developing the Pharmaceutical Industry through Artificial Intelligence [0.03%]
全面调查：通过人工智能发展制药产业
Deepak Jain,Phool Chandra,Zeeshan Ali et al.
Deepak Jain et al.
AI's rise has affected many aspects of civilization. Pharmaceutical businesses have been hit hard. This review paper highlights AI's benefits for disease detection, clinical trials, medicine development, and productivity in the pharmaceutic...