Manvi Karayat,Kalpana Rahate,Shristi Singh
Manvi Karayat
An imbalance between Reactive Oxygen Species (ROS) and antioxidants in the circulatory system leads to oxidative stress, which has been linked to several pathological conditions, including cancer, aging, and neurological and cardiovascular ...
Targeted Management: Unlocking the Crucial Role of PROTACs in Cancer Treatment [0.03%]
靶向管理：PROTACs在癌症治疗中的关键作用解析
Priyanka Gupta,Sumit Dutta,Prashant Kumar et al.
Priyanka Gupta et al.
Targeted Protein Degradation (TPD) offers a solution, eliminating disease-related proteins and overcoming challenges associated with unintended toxicity and lack of precision. PROTACs (Proteolysis Targeting Chimeras) represent an innovative...
An Overview of Unlocking the Power of Non-Coding RNAs in Revolutionizing Cancer Therapy [0.03%]
非编码RNA在革命性癌症治疗中力量的概述
Sagarika Kabra,Neetu Sharma,Ankita Kumari et al.
Sagarika Kabra et al.
Non-coding RNA (ncRNA) has been recognized to be an essential regulator of cellular processes and gene expression in cancer. The present study covers the various roles of ncRNAs, including circular RNAs (circRNAs), long non-coding RNAs (lnc...
Evaluation of Cytotoxicity and Antimicrobial Activity of Thanatin Recombinant Peptide against Some Oral Bacteria: A Novel Approach against Bacterial Pathogens in Dentistry [0.03%]
Thanatin重组肽对口腔某些细菌细胞毒性和抗菌活性的评价：牙科学中对抗细菌病原体的一种新方法
Atefeh Nemati Karimooy,Mohammad Jarchi,Fatemeh Forouzanfar et al.
Atefeh Nemati Karimooy et al.
Objective: This study investigated the antimicrobial properties of the thanatin peptide against oral bacteria associated with dental caries and endodontic failures. Additionally, the cytotoxic effects of this peptide on h...
Virtual Screening and Identification of Novel Oxindole Derivatives as Potential Antimicrobial Agents [0.03%]
虚拟筛选和鉴定新型噁吲哚衍生物作为潜在的抗菌剂
Sowmiya P,Revathi G,Girija K
Sowmiya P
Introduction: Antimicrobial resistance (AMR), according to the World Health Organi-zation, is one of the most serious risks to global public health and development. It is a serious health hazard, with over 10 million deat...
In-Silico Approaches for Drug Designing Technology: Bridging Discovery and Development [0.03%]
药物设计技术的计算机模拟方法：连接发现与开发
Aminul Islam,Diptimayee Jena,Nur Shaid Mondal et al.
Aminul Islam et al.
Traditional drug discovery processes have disadvantages such as efficiency, cost, and high attrition rates. In silico methods, involving computational simulations and modelling, offer powerful solutions to bridge the gap between discovery a...
Revolutionizing Drug Development: Harnessing Artificial Intelligence in Pharmaceutical Sciences [0.03%]
革命性药物开发：在药学科学中利用人工智能的力量
Samaresh Pal Roy,Sunil Kumar Kadiri,Suchismita Bhowmik et al.
Samaresh Pal Roy et al.
The integration of artificial intelligence (AI) in pharmaceutical sciences marks a signifi-cant milestone in the field of drug discovery and development, presenting unique prospects for crea-tivity and productivity. This review article delv...
Amit Lather,Pratibha Rathee,Manish Kumar Gautam et al.
Amit Lather et al.
Diabetes is a chronic metabolic disease of high levels of glucose in the blood and affecting 536.6 million people in the world between the age group of 20-79 with management spent of 11% of the total worldwide. Wound healing in diabetics is...
In-silico Approach to Combat Methicillin-resistant Staphylococcus aureus: Targeting RelP Protein with Inhibitor Peptide to Mitigate Drug Resistance [0.03%]
对抗耐甲氧西林金黄色葡萄球菌的计算机模拟方法：用抑制肽针对RelP蛋白以减轻药物抗性
Priyanka Sinoliya,Pooran Singh Solanki,Ravi Ranjan Kumar Niraj et al.
Priyanka Sinoliya et al.
Background: Methicillin-resistant Staphylococcus aureus (MRSA), known for its re-sistance to multiple antibiotics, has emerged as a major global health concern. It facilitates biofilm formation under stressful conditions ...
Dinesh Kumar,Rajni Tanwar,Raj Kamal et al.
Dinesh Kumar et al.