Neuropharmacological Interventions of Plant Origin for Parkinson's Disease: A Comprehensive Appraisal [0.03%]
植物来源的帕金森病神经药理学干预措施的全面评估
Umar Muzaffer,Bisma Gull,Zabeer Ahmed et al.
Umar Muzaffer et al.
Parkinson's disease (PD) presents a complex challenge in neurodegenerative disorders, necessitating innovative therapeutic approaches. This review article elucidates the therapeutic potential of traditional herbal formulations alongside com...
The Status and Future Directions of Treatments for Polyglutamine Spinocerebellar Ataxia: A Bibliometric and Visual Analysis [0.03%]
聚谷氨酰胺自-spinocerebellar共济失调治疗现状与未来方向的计量可视化分析
Siyu Ding,Linliu Peng,Zhao Chen et al.
Siyu Ding et al.
Background: Polyglutamine (polyQ) spinocerebellar ataxias (SCA) are a group of autosomal dominant neurodegenerative disorders for which no effective treatments currently exist. These conditions impose a significant burden...
Windows to Consciousness: The Role of Fronto-Parietal Connectivity in Anesthesia-Induced Unconsciousness [0.03%]
通向意识的窗口： frontal-parietal连接在麻醉引起的无意识状态中的作用
Yuanyuan Ding,Shiya Liu,Kaixin Wang et al.
Yuanyuan Ding et al.
The exploration of consciousness and the elucidation of the mechanisms underlying general anesthesia are two intertwined endeavors that have significantly advanced our understanding of the neural correlates of awareness. Both fields converg...
Celastrol Ameliorates Vincristine-induced Neuropathic Pain by Inhibiting Spinal Astrocyte Hyperactivation-mediated Inflammation, Oxidative Stress, and Apoptosis [0.03%]
雷公藤红素通过抑制脊髓星形胶质细胞过度活化介导的炎症、氧化应激和凋亡来缓解长春新碱诱导的神经病理性疼痛
Gui-Zhou Li,Jing Xu,Yun-Man Li et al.
Gui-Zhou Li et al.
Background: Neurotoxicity is the severe adverse reaction induced by chemotherapy drugs, characterized by neuropathic pain. However, there is a notable lack of therapeutic drugs for chemotherapy-induced neuropathic pain (C...
Translational Informatics for Neuropharmacology: Databases, Ontologies, and Analytics [0.03%]
神经药理学的转化信息学：数据库、本体和分析方法
Bairong Shen,Nigel H Greig,Mohammad Amjad Kamal
Bairong Shen
The Evolution of Machine Learning in Medicinal Chemistry: A Comprehensive Bibliometric Analysis [0.03%]
药物化学领域机器学习的 bibliometric分析及进化历程综述
Yanhua Wang,Tongxin Guan,Dongyu Xu et al.
Yanhua Wang et al.
Introduction: In the medicinal chemistry (MC) field, artificial intelligence (AI) has been used to establish quantitative structure-activity relationship (QSAR) classification models, virtual screening, drug discovery, dr...
Research Trends and Knowledge Atlas of Radiotherapy-Related Cognitive Impairment: A Bibliometric Analysis [0.03%]
放射治疗相关性认知障碍研究趋势和知识图谱的 bibliometrix 分析
Yaqian Tan,Qi Song,Siyuan Gao
Yaqian Tan
Background: Radiotherapy is one of the main therapeutic methods for tumors, and radiation- related cognitive impairment has attracted increasing attention. The purpose of this study was to explore the research prospects i...
Hydroxychloroquine Prevents High-altitude Cerebral Edema by Inhibiting Endothelial Claudin-5 Autophagic Degradation [0.03%]
羟氯喹通过抑制内皮紧密连接蛋白Claudin-5的自噬降解预防高原脑水肿
Yan Xue,Baolan Wan,Zhen Wang et al.
Yan Xue et al.
Background: High-altitude cerebral edema (HACE) is a serious condition caused by pro-longed hypobaric hypoxia (HH). Autophagic degradation of Claudin-5 plays a crucial role in HH-induced blood-brain barrier (BBB) damage. ...
Excessive Urinary p75ecd is a Potential Indicator of Amyotrophic Lateral Sclerosis: An American Cohort Study [0.03%]
尿液p75ecd过多可能是肌萎缩侧索硬化症的潜在指标：一项美国队列研究
Swati Dhasmana,Anupam Dhasmana,Sheema Khan et al.
Swati Dhasmana et al.
Introduction: Amyotrophic lateral sclerosis (ALS) is an idiopathic, fatal, and rapidly progressive neurodegenerative disease. At present, neurofilament light (NFL) and phosphorylated neurofilament heavy (pNfH) proteins in...
The Mechanisms and Application Prospects of Astrocyte Reprogramming into Neurons in Central Nervous System Diseases [0.03%]
中枢神经系统疾病条件下星形胶质细胞重编程为神经元的机制及应用前景
Rongxing Qin,Xinyu Lai,Wei Xu et al.
Rongxing Qin et al.
Central nervous system (CNS) diseases, including ischemic stroke (IS), Alzheimer's disease (AD), and Parkinson's disease (PD), are leading causes of global disability and mortality, characterized by progressive neuronal loss and irreversibl...