Sustained Reduction of Dystonic Tremor and Pain after Cannabis Oil Administration and Physiotherapy in Thalamic Ischemia: A One-Year Case Report [0.03%]
大脛动脉梗死后的持续性肌张力障碍震颤和疼痛缓解：一年期病例报告
Enrico Buccheri,Salvatore Caramma,Rita Chiaramonte et al.
Enrico Buccheri et al.
Introduction: Post-stroke tremor and post-stroke thalamic pain (PS-TP) are common and often refractory conditions that significantly impact patients' quality of life. Conventional pharmacotherapy frequently provides inade...
Mitochondrial and Antioxidant Activity as the Basis of the Neuroprotective Effect of Potential Multitarget Drugs for the Treatment of Neurodegenerative Diseases [0.03%]
线粒体和抗氧化作用作为潜在多靶点神经保护药物治疗神经退行性疾病的基础神经保护效应
Elena Feofanovna Shevtsova,Alexey Yuryevich Aksinenko,Alla Vadimovna Stavrovskaya et al.
Elena Feofanovna Shevtsova et al.
Background: The mechanisms of neurodegeneration common to many neurodegenerative diseases include oxidative stress, mitochondrial dysfunctions, excitotoxicity, and others. Beyond the broad spectrum of strategies for devel...
Blockade of Interleukin-6 Receptor with Tocilizumab During the Acute Phase of Childhood Immune-Mediated Epilepsy can Lead to a Favorable Outcome - an Observational Study [0.03%]
托珠单抗阻断白细胞介素-6受体可改善儿童获得性免疫性癫痫急性期的临床症状：一项观察性研究
Xiaolu Deng,Jielu Tan,Miriam Kessi et al.
Xiaolu Deng et al.
Introduction: To explore the role of tocilizumab in treating childhood immune-mediated epilepsy and determine the role of interleukin-6 (IL-6) in its pathogenesis. ...
Efgartigimod in Very-Late-Onset Generalized Myasthenia Gravis: A Real-World Study on Effectiveness and Safety [0.03%]
艾加替莫德治疗迟发型全身性重症肌无力的疗效和安全性的真实世界研究
Chi Ma,Jingyi Shen,Ying Zhu et al.
Chi Ma et al.
Introduction: This study evaluated the safety and effectiveness of efgartigimod in patients with Very-Late-Onset Generalized Myasthenia Gravis (VLOGMG), a population that often presents with more severe symptoms and limit...
Investigating the Multiple Regulatory Mechanisms and Therapeutic Targets of PHLDA1 in Neurological Diseases [0.03%]
PHLDA1在神经疾病中的多重调控机制及治疗靶点研究
Xiaodong Liu,Zhengxiang Lv,Gaoyuan Xu et al.
Xiaodong Liu et al.
PHLDA1 (pleckstrin homology-like domain family A member 1) is a pleiotropic regulatory protein that affects key biological processes such as apoptosis, pyroptosis, immune inflammation, autophagy, metabolism, and oxidative stress. PHLDA1 pla...
Associations Among Binge Eating Behaviors, Emotion Regulation, and Chronotype in Female Greek University Students [0.03%]
希腊女大学生之间 binge eating行为、情绪调节和昼夜型的相关性研究
Efi Karakosta,Evangelia-Maria Tsapakis,Anastasia Konsta et al.
Efi Karakosta et al.
Introduction: This study aimed to examine the associations among binge eating behaviors (BEBs), emotion regulation (ER), and chronotypes, and whether ER mediates the relationship between chronotypes and BEBs in Greek fema...
The Role and Diagnostic Value of Astrocyte-Derived Exosomes in Ischemic Stroke [0.03%]
缺血性卒中源星形胶质细胞外泌体的作用及诊断价值
Si-Rou Wang,Li-Hua Zhu,Jia-Hao Jiang et al.
Si-Rou Wang et al.
Ischemic Stroke (IS) is a central nervous system disease caused by cerebrovascular obstruction. It is associated with high mortality and disability rates, few available treatments, and a poor prognosis. Exosomes secreted by neuronal cells h...
Sleep Disorders in Moyamoya Disease: Prevalence, Risk Factors, and Impact on Functional Outcomes [0.03%]
moyamoya病的睡眠障碍：患病率、危险因素及对功能预后的影响
Qingbao Guo,Manli Xie,Dan Yu et al.
Qingbao Guo et al.
Introduction: Sleep disorders are prevalent but frequently overlooked in Moyamoya Disease (MMD), with their clinical impact remaining inadequately characterized. This study aimed to determine the prevalence of sleep disor...
Overall and Sex-Based Risk Factors for Hyperprolactinemia in Patients With Schizophrenia: A Retrospective Cohort Study [0.03%]
精神分裂症患者高催乳素血症的整体和性别差异的风险因素：回顾性队列研究
Yan Yang,Xiaoqin Chen,Zhenjing Liu et al.
Yan Yang et al.
Background: Hyperprolactinemia (HPRL) can lead to various health complications. Among patients with schizophrenia, it may be linked to antipsychotic medications and other contributing factors. Sex-based differences in HPR...
CRISPR in Alzheimer's Disease: Engineering Genetic Solutions for Neurodegenerative Resilience [0.03%]
CRISPR在阿尔茨海默病中的应用：工程化遗传解决方案以增强神经退行性抵抗能力
Roshan Shah,Zheng Tao,Yuanyuan Wang et al.
Roshan Shah et al.
Alzheimer's Disease (AD), the primary etiology of dementia, remains a considerable challenge owing to the limited availability of pharmacological interventions that effectively modify the course of the disease. This review evaluates CRISPR/...