Betaine: A Promising Natural Product for Neurological and Psychiatric Diseases [0.03%]
天然产物甜菜碱在神经和精神疾病中的应用前景
Ying Zhang,Zhaojuan Ke,Jie Luo et al.
Ying Zhang et al.
Neurological and psychiatric diseases pose a considerable global burden. Exploring additional potential prevention strategies and therapies is ongoing. As a prevalent natural product and nutraceutical from food, betaine's pharmaceutical app...
Inhibition of the P2Y2 Receptor Promotes Facial Nerve Function by Enhancing Neuron Autophagy [0.03%]
P2Y2受体抑制通过促进神经元自噬促进面神经功能修复
Xianmin Song,Yingna Gao,Minhui Zhu et al.
Xianmin Song et al.
Objective: Facial nerve injury induces autophagy and apoptosis in facial nerve nucleus motoneurons of the CNS, impairing nerve regeneration and functional recovery. The function of P2Y2R after facial nerve injury remains ...
Mediterranean Pattern Diet in Multiple Sclerosis: A Review Focusing on Immunometabolites [0.03%]
地中海饮食模式在多发性硬化症中的作用:以免疫代谢物为重点的综述
Giulio Papiri,Cristina Paci,Giordano Dandreamatteo et al.
Giulio Papiri et al.
Multiple Sclerosis (MS), the most common demyelinating disease of the Central Nervous System (CNS), is characterized in its pathogenesis by an interplay of mechanisms pertaining to aberrant immune response, acute and chronic inflammation, g...
Daridorexant and Insomnia in Clinical Practice: A Nominal Group Technique Consensus Study among Italian Sleep and Insomnia Experts [0.03%]
Daridorexant与临床实践中的失眠:意大利睡眠和失眠专家共识研究的名义小组技术
Luigi Ferini Strambi,Dario Arnaldi,Enrica Bonanni et al.
Luigi Ferini Strambi et al.
Introduction: Chronic insomnia disorder significantly affects cognitive, emotional, and physical health. Recently, the dual orexin receptor antagonist (DORA) daridorexant was approved for treating chronic insomnia in seve...
A Prospective Clinical Trial of Efgartigimod for New-Onset Generalized Myasthenia Gravis [0.03%]
Efgartigimod治疗初发全身型重症肌无力的前瞻性临床试验
Chi Ma,Jingyi Shen,Ying Zhu et al.
Chi Ma et al.
Introduction: Numerous studies have demonstrated that efgartigimod is effective in treating myasthenia gravis (MG) across various patient populations. However, there is limited evidence regarding its use in patients with ...
Corrigendum to: "Effects of Alcohol on EEG Activity: A Systematic Review Focused on Sex-Related Differences in Youth" [0.03%]
关于“酒精对脑电活动的影响:以青年性别差异为重点的系统评价”的更正
Adrián S Elliott,Román D Moreno-Fernández,Patricia Sampedro-Piquero
Adrián S Elliott
In the original publication of this article titled, "Effects of Alcohol on EEG Activity: A Systematic Review Focused on Sex- Related Differences in Youth", published in Current Neuropharmacology, 2025, 06, 705-727 [1] the citation of Figs. ...
MicroRNAs as Potential Biomarkers and Therapeutic Targets in Ischemic Stroke from the Perspective of Inflammation [0.03%]
从炎症角度探讨缺血性卒中潜在生物标志物和治疗靶点的微小核糖核酸研究
Nai-He Chen,Jia-Xin Ren,Guang-Jian Li et al.
Nai-He Chen et al.
Ischemic stroke, triggered by the interruption of cerebral blood flow, initiates a complex inflammatory process involving both brain-resident and peripheral immune cells. Microglia, the primary brain-resident immune cells of high heterogene...
Analyses of Nogo-Family Genes in Mouse and Human Microglia Omics Datasets Identify LINGO1 as a Candidate Drug Target in Alzheimer's Disease [0.03%]
对小鼠和人类微胶质细胞组学数据集中的Nogo家族基因的分析确定LINGO1为阿尔茨海默病的候选药物靶点
Glotfelty Elliot J,Tobias E Karlsson,Lars Olson et al.
Glotfelty Elliot J et al.
Microglia are the innate immune cells of the brain. Recent single-cell and nucleus sequencing, along with other omics technologies, are leading the way for discoveries related to microglial function and diversity. The Nogo-signaling system ...
Advancing Alzheimer's Diagnosis with AI-Enhanced MRI: A Review of Challenges and Implications [0.03%]
利用人工智能增强的MRI推进阿尔茨海默病诊断:挑战与影响综述
Zahra Batool,ShanShan Hu,Mohammad Amjad Kamal et al.
Zahra Batool et al.
Neurological disorders are marked by neurodegeneration, leading to impaired cognition, psychosis, and mood alterations. These symptoms are typically associated with functional changes in both emotional and cognitive processes, which are oft...
Efficacy of Venlafaxine and Deep Brain Stimulation Against the Effects of Hippocampal Lesion with Ibotenic Acid in Animals Exposed to the Chronic Mild Stress Model of Depression [0.03%]
威拉富辛和深部脑刺激对抗慢性轻度应激模型大鼠腹侧海马损伤引起的抑郁样行为的效果的比较研究
Litwa Ewa,Bartosz-Nowakowska Aleksandra,Bobula Bartosz et al.
Litwa Ewa et al.
Introduction: Dysfunction of the pathway between the ventral hippocampus (vHPC) and medial prefrontal cortex (mPFC) may be responsible for the weaker or lack of efficacy of antidepressant drugs in patients suffering from ...