The Role of Nanotechnology in Understanding the Pathophysiology of Traumatic Brain Injury [0.03%]
纳米技术在理解创伤性脑损伤病理生理学中的作用
Saranya Selvaraj,Laksiri Weerasinghe
Saranya Selvaraj
Recently, traumatic brain injury (TBI) has been a growing disorder due to frequent brain dysfunction. The Glasgow Coma Scale expresses TBI as classified as having mild, moderate, or severe brain effects, according to the effects on the brai...
A Review on Tau Targeting Biomimetics Nano Formulations: Novel Approach for Targeting Alzheimer's Diseases [0.03%]
针对Tau蛋白的仿生纳米制剂的研究进展：治疗阿尔茨海默病的新策略
Aditya Singh,Shubhrat Maheshwari,Jagat Pal Yadav et al.
Aditya Singh et al.
Central nervous system disorders are prevalent, profoundly debilitating, and poorly managed. Developing innovative treatments for these conditions, including Alzheimer's disease, could significantly improve patients' quality of life and red...
Filtration of Natural Derivatives as MAO Inhibitors by Virtual Screening: A Potential Lead for Neurodegenerative Disorders [0.03%]
基于虚拟筛选的天然产物MAO抑制剂研究及其神经退行性疾病治疗潜力评估项目
Neelam Malik,Supriya Agnihotri,Priyanka Dhiman
Neelam Malik
Aim: The purpose of the current study was to explore the virtual library for the screening against Monoamine oxidase (MAO) isoforms. An in-house library of natural based ligands was docked within the active sites of MAO i...
WITHDRAWN: Exploring The Diverse Therapeutic Potentials of Synthetic Analogues of Keto-terpenoids (+) Carvone: A Future Scaffold [0.03%]
撤稿：合成酮类单萜类似物（+）右旋薄荷酮的多种治疗潜力：未来的药物支架
Snigdha Srivastava,Reema Sinha,Rahul Kaushik et al.
Snigdha Srivastava et al.
The article has been withdrawn at the request of the authors of the journal "Central Nervous System Agents in Medicinal Chemistry" as a conflict has arisen among the authors in adding another author at the later stage of publication ...
Current Concepts in the Molecular Mechanisms and Management of Diabetic Neuropathy by Pharmacotherapeutics and Natural Compounds [0.03%]
药物治疗和天然化合物分子机制及糖尿病神经病变管理的最新概念
Shivam,Asheesh Kumar Gupta,Sushil Kumar
Shivam
One of the most crippling effects of diabetes mellitus is diabetic neuropathy, which can cause discomfort, loss of movement, and even amputation. Diabetic neuropathy manifests in a variety of ways, ranging from pain to death. Diagnosing dia...
Kalyani Pathak,Mohammad Zaki Ahmad,Riya Saikia et al.
Kalyani Pathak et al.
Alzheimer's disease (AD) is a prevalent neurodegenerative disorder affecting elderly individuals, characterized by progressive cognitive decline leading to dementia. This review examines the challenges posed by anatomical and biochemical ba...
Farshad Hassanzadeh Kiabi,Saeed Gharooee Ahangar,Siavash Beiranvand
Farshad Hassanzadeh Kiabi
One essential component of the neurovascular system is known as the blood-brain barrier (BBB). This highly effective biological barrier plays a pivotal role in regulating the brain's internal microenvironment and carefully controlling the p...
Iqra Subhan,Yasir Hasan Siddique
Iqra Subhan
Resveratrol is a biologically active natural phenolic plant product. It has several properties which make them useful to treat the disease. In this review, we have highlighted the neuroprotective effects of resveratrol. Several available an...
The Role of Ocimene in Decreasing α-Synuclein Aggregation using Rotenone-induced Rat Model [0.03%]
倍半花烃在罗登铵诱导的大鼠模型中通过减少α-突触核蛋白的聚集而起的作用
Ankul Singh S,Aarita Sood,Chitra Vellapandian
Ankul Singh S
Background: Parkinson's disease is defined by the loss of dopaminergic neurons in the midbrain of substantia nigra associated with Lewy bodies. The precise mechanism is not yet entirely understood. ...
Effectiveness of Novel Drug Delivery System using Curcumin in Alzheimer's Disease [0.03%]
使用姜黄素的新药物输送系统在阿尔茨海默病中的有效性
Aswar Urmila,Rathod Kundlik,Dyandevi Mathure
Aswar Urmila
Alzheimer's disease (AD) is a form of brain degeneration that gradually impairs a person's memory and cognitive skills, eventually making it harder for them to perform everyday activities. Its pathophysiology has been attributed to the depo...