D-galactose-induced Cognitive Impairment: Mechanism, Models and Therapeutic Interventions [0.03%]
D-半乳糖诱导的认知障碍：机制、模型和治疗干预措施
Tanisha Chaudhary,Sagarika Majhi,Meenakshi Sharma
Tanisha Chaudhary
Age is the main risk factor for cognitive impairment, a degenerative disorder marked by deficiencies in memory, learning, and executive function. Although natural ageing research necessitates longer timeframes, animal models are crucial for...
Cardiospermum halicacabum: A Scoping Review on its Phytoactives, Neuroprotective, Anti-Inflammatory, and Antioxidant Potential [0.03%]
卡氏鼓子花的化学成分、药理作用及质量标志物的研究进展
Himangi Vig,Anuradha Mishra,Ankita Wal
Himangi Vig
Introduction: Cardiospermum halicacabum, commonly known as balloon vine or love in a puff, is a medicinal plant recognized for its diverse phytoactive compounds. This plant contains various bioactive constituents, includi...
Therapeutic Insights into Natural Products for Modulating Neurodegenerative Disease Pathways [0.03%]
天然产物调节神经退行性疾病发病途径的治疗研究新见
Anjali Sharma,Vishnu Mittal,Devkant Sharma et al.
Anjali Sharma et al.
Introduction: Neurodegenerative Disorders (NDs), such as Alzheimer's disease, Parkinson's disease, Huntington's disease, and Amyotrophic Lateral Sclerosis (ALS), are chronic and progressive conditions marked by the gradua...
Translational Perspectives on Anti-Inflammatory Interventions for Neurodegenerative Disorders: Evidence from Gut-Brain Axis [0.03%]
从肠-脑轴证据看神经退行性疾病抗炎干预的转化研究视角
Vasundhara Saxena,Vishwadeep Singh,Sanskriti
Vasundhara Saxena
The Gut-Brain Axis (GBA) has a complex role in chronic neuroinflammation, which is increasingly connected to neurodegenerative diseases (NDDs) such as Multiple Sclerosis (MS), Parkinson's Disease (PD), and Alzheimer's Disease (AD). Through ...
Unveiling the Neuroprotective Role of Nutritional Supplements in Neurodegenerative Diseases [0.03%]
营养补充剂在神经退行性疾病中神经保护作用的揭示
Sonia Singh
Sonia Singh
Nutraceuticals obtained from natural sources have been explored as well as studied for significant applications to treat several diseases like diabetes, cardiovascular diseases, and neurodegenerative diseases. The manuscript explores the mo...
Ferulic Acid- and Quercetin-based Extracts Enhanced Neuropharmacological Potential in Swiss Albino Mice: Molecular Dynamics Simulation,mMolecular Docking, ADMET, and Biological Investigation [0.03%]
基于香豆酸和山柰酚的提取物增强了瑞士白化鼠标神经药理潜能：分子动力学模拟，分子对接，ADMET及生物研究
Bhawna Shridhar,Jatin Kishore Sharma,Akhlesh Kumari et al.
Bhawna Shridhar et al.
Introduction: Neurological disorders impair cognitive, emotional, and behavioural functions, leading to a reduced quality of life. Due to the limitations of conventional therapies, the present study aimed to develop and e...
Neuroprotective Role of Exercise-based Physiotherapy Combined with Pharmacological Agents in Parkinson's Disease [0.03%]
运动物理疗法联合药物治疗在帕金森病中的神经保护作用
Divya Aggarwal,Nitesh Malhotra,Pooja Sharma et al.
Divya Aggarwal et al.
Introduction: The progressive neurodegenerative disease known as Parkinson's Disease (PD) is represented by deficits in both motor and non-motor functions. Levodopa and dopamine agonists are examples of pharmaceutical tre...
Hydrogel-forming Microneedles: A Next-generation Approach for Enhanced Dermal Drug Delivery in Alzheimer's and Neurological Disorders [0.03%]
水凝胶形成微针：阿尔茨海默病和神经系统疾病经皮给药的新一代方法
Jayaramakani Natarajan,Srinivasan Ranganathan
Jayaramakani Natarajan
Hydrogel-Forming Microneedles (HFMNs) offer a minimally invasive, patient-friendly, and sustained-release platform for transdermal delivery. By swelling upon insertion to form a hydrogel matrix, they enable efficient delivery of small molec...
Emerging Therapies and Research in Alzheimer's Disease: A Critical Review [0.03%]
阿尔茨海默病的新兴疗法和研究：批判性综述
Madan Mohan Agrawal,Payal Mittal
Madan Mohan Agrawal
Alzheimer's disease, an extremely prevalent neurological illness and the leading cause of dementia globally, is an extremely prevalent neurological illness and is the leading cause of dementia globally. There are a few treatment options for...
A Systematic Review on Isoquinoline Derivatives as Emerging Multi-target Agents in Alzheimer's and Parkinson's Disorder Therapy [0.03%]
异喹啉衍生物作为阿尔茨海默病和帕金森氏症治疗新兴多靶向剂系统评价
Indrakumar Subramanian,Remya Ramachandran Surajambika,Dibenthiran Sekar et al.
Indrakumar Subramanian et al.
Introduction: Neurodegenerative disorders, including Alzheimer's, Parkinson's, multiple sclerosis, amyotrophic lateral sclerosis, and Huntington's disease, are characterized by progressive neuronal loss driven by damage o...