Ashwani Arya,Manish Dhall,Vineet Mittal et al.
Ashwani Arya et al.
Multiple sclerosis (MS) is an unceasing, demyelinating, idiopathic inflammatory, and neurodegenerative disease of the Central Nervous System (CNS.) The disease is characterized by the occurrence of neurological symptoms over a period of day...
Unveiling the Mysteries of the Blood-Brain Barrier: The Problem of the Brain/spinal Pharmacotherapy [0.03%]
揭开血脑屏障的神秘面纱——中枢神经系统药物治疗的困境
Aditya Walia,Amandeep Kaur,Randhir Singh et al.
Aditya Walia et al.
The most critical issue impeding the development of innovative cerebrospinal medications is the blood-brain barrier (BBB). The BBB limits the ability of most medications to penetrate the brain to the CNS. The BBB structure and functions are...
Unraveling the Plausible Role of Potassium Channel Openers in Alzheimer's Disease [0.03%]
钾通道开启剂在阿尔茨海默病中可能作用的再思考
Sarvesh Kumar,Bhupesh Sharma,Anjana Sharma et al.
Sarvesh Kumar et al.
Significance of Neurotransmitters in Cerebral Ischemia: Understanding the Role of Serotonin, Dopamine, Glutamate, and GABA in Stroke Recovery and Treatment [0.03%]
神经递质在脑缺血中的意义：了解5-羟色胺、多巴胺、谷氨酸和γ-氨基丁酸在卒中恢复和治疗中的作用
Marjan Nikbakhtzadeh,Sanaz Bordbar,Samaneh Seyedi et al.
Marjan Nikbakhtzadeh et al.
Brain ischemia occurs following heart failure, thromboembolism, and atherosclerosis, and it is characterized by the disturbance of blood flow resulting from the blockage of blood vessels. After a series of studies, it is deduced that variou...
Mohammad Amin Forqani,Mahsan Akbarian,Sabiheh Amirahmadi et al.
Mohammad Amin Forqani et al.
Background: Aging affects cellular functions and impairs tissue homeostasis. Carvacrol, a polyphenolic compound, has been shown to exert a wide range of pharmacological effects, such as antioxidant, anti-inflammatory, and...
Rimjhim Priyanshi,Anjana Sharma,Shobhit Kumar et al.
Rimjhim Priyanshi et al.
Background: Neuropathic pain is a complex chronic condition resulting from the damage or dysfunction of the nervous system. Conventional therapies offer limited success and often come with various adverse effects. Therefo...
A Systematic Review of the Anti-seizure and Antiepileptic Effects and Mechanisms of Piperine [0.03%]
胡椒碱的抗惊厥和抗癫痫作用及机制的系统评价
Nasim Rahimi-Dehkordi,Saeid Heidari-Soureshjani,Sahar Rostamian
Nasim Rahimi-Dehkordi
Introduction and aim: Seizures due to epilepsy in any form cause a wide range of problems in a patient's physical, psychological, and social health. This study aimed to investigate piperine's anti-seizure and antiepilepti...
Targeting Adenylate Cyclase: A Novel Concept for Stimulation of Neurogenesis and Pharmacotherapy of Alzheimer's Disease [0.03%]
瞄准腺苷酸环化酶：促进神经发生及阿尔茨海默病药理治疗的新概念
Gleb Nikolaevich Zyuz&#x;kov,Larisa Arkad Evna Miroshnichenko,Tatyana Yur Evna Polykova et al.
Gleb Nikolaevich Zyuz&#x;kov et al.
Background: The low effectiveness of existing pharmacotherapy strategies for Alzheimer's disease (AD) makes it necessary to develop a new concept for the treatment of this type of dementia. This search is promising to be ...
A Comprehensive Review of the Pharmacological Effects of Genus Ferula on Central Nervous System Disorders [0.03%]
Ferula属药物对中枢神经系统疾病的药理作用综述
Seyyed Majid Bagheri,Mansour Esmailidehaj
Seyyed Majid Bagheri
Background: Plants of the genus Ferula have long been used to treat neurological diseases such as Alzheimer's disease (AD), pain, depression, and seizures. The main compounds include coumarins, monoterpenes, sulfide compo...
Beta-Site APP-Cleaving Enzyme-1 Inhibitory Role of Natural Flavonoids in the Treatment of Alzheimer's Disease [0.03%]
天然黄酮类化合物在阿尔茨海默病治疗中对β-分泌酶位点APP切割酶的抑制作用
Sandeep Singh,Virendra Kushwaha,Shriram Sisodia et al.
Sandeep Singh et al.
Alzheimer's Disease (AD) is a devastating neurological condition characterized by a progressive decline in cognitive function, including memory loss, reasoning difficulties, and disorientation. Its hallmark features include the formation of...