An Overview of Antihistamines and their Properties used for Treatment of Different Diseases [0.03%]
抗组胺药及其用于不同疾病治疗的性质概述
Riya Chaudhari,Seema Gosavi,Pratiksha Bornare et al.
Riya Chaudhari et al.
Background: By comparing the histamine impact to the instant response to an injected foreign protein in previously sensitized animals, one might hypothesize that histamine may be involved in this reaction. Through all fou...
Development of 7H-pyrrolo[2,3-d]pyrimidin-4-amine Derivatives Using QSARINS Tool as BTK Inhibitors for the Treatment of Rheumatoid Arthritis [0.03%]
使用QSARINS工具开发7H-吡咯并[2,3-D]嘧啶-4-胺衍生物作为治疗类风湿关节炎的BTK抑制剂的发展
Shital M Patil,Kalyani D Asgaonkar,Pradnya Magdum et al.
Shital M Patil et al.
Background: Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation of the joints, leading to pain, swelling, and joint deformity. Effective management of RA involves the use of disease-mod...
1,3-Thiazole Derivatives as a Promising Scaffold in Medicinal Chemistry: A Recent Overview [0.03%]
医药化学中1,3-噻唑衍生物作为有前景的骨架的一个近况综述
Pragati Kushwaha,Shashi Pandey
Pragati Kushwaha
The thiazole ring is a unique heterocyclic motif among heterocyclic compounds. This five-member ring with one nitrogen and one sulphur atom displays a wide array of pharmacological activities, including anti-inflammatory, antimicrobial, ant...
Yuflyma, A High Concentration and Citrate-free Adalimumab Biosimilar, Received FDA Approval for Treating Different Forms of Inflammato ry Diseases [0.03%]
优宜单抗，一种高浓度和无柠檬酸盐的阿达木单抗类似药，获得FDA批准用于治疗不同类型的炎症性疾病
Vinod Kumar Rajana,Sudha Madhavi Penumaka,Cevella Saritha et al.
Vinod Kumar Rajana et al.
Manos C Vlasiou
Manos C Vlasiou
Juglone Mediates Inflammatory Bowel Disease Through Inhibition of TLR-4/NF KappaB Pathway in Acetic Acid-induced Colitis in Rats [0.03%]
胡桃醌通过抑制Toll样受体4/核因子κB信号通路介导丙酸诱导的大鼠结肠炎炎症反应
Neda Agha Alizadeh Nobakht,Naser-Aldin Lashgari,Nazanin Momeni Roudsari et al.
Neda Agha Alizadeh Nobakht et al.
Background: Juglone is a phenolic bioactive compound with antimicrobial, antitumour, antioxidant, and anti-inflammatory characteristics. Given its anti-inflammatory and antioxidant effects, it was selected for evaluation ...
Wound Healing, Anti-inflammatory and Antioxidant Potential of Quercetin Loaded Banana Starch Nanoparticles [0.03%]
纳米载荷芸香素的香蕉淀粉纳米颗粒的伤口愈合、抗炎和抗氧化潜力
Dharmendra Kumar,Pramod Kumar Sharma
Dharmendra Kumar
Background: Quercetin belongs to the BCS Class IV of drugs, which means it exhibits low solubility and low permeability. Quercetin is a potent antioxidant drug candidate, but it has several drawbacks, such as a short half...
Hydroxypropyl Methylcellulose Orodispersible Film Containing Desloratadine for Geriatric Use: Formulation and Evaluation [0.03%]
含地氯雷他定的羟丙甲纤维素口服速溶膜的处方前研究及评价
Aya Yahya Fayez Al-Oran,Evrim Yenilmez
Aya Yahya Fayez Al-Oran
Background: Oral strip is very similar to thin strip of postage stamp in shape, size and thickness. The strip is designed to be placed on the tongue or any oral mucosal tissue which immediately gets wet and hydrated after...
Prepubertal Continuous Dietary Folate Fortification Enhances the Brain Function of Adult Mice by Modulating Antioxidant Status, Inflammation, and Brain Neurotransmitter Levels [0.03%]
孕期持续叶酸强化通过调节抗氧化状态、炎症和大脑神经递质水平来增强成年小鼠的大脑功能
Olakunle J Onaolapo,Anthony T Olofinnade,Folusho O Ojo et al.
Olakunle J Onaolapo et al.
Background: The benefits of folic acid supplementation have been documented in several studies. However, while evidence exists regarding its benefits for growth and haematologic parameters, its possible effects on the bra...
Immunomodulatory Effects of Combined Nicotinic Acid and Prednisolone in Adjuvant-induced Arthritis [0.03%]
烟酸和泼尼松龙联合的免疫调节作用研究对佐剂性关节炎的影响
Shadan Mirzaaghasi,Seyyed Meysam Abtahi Froushani
Shadan Mirzaaghasi
Background: The combination of two drugs may lead to better results while reducing the need for each medication. Objective: This study ...