Benzothiazole Derivatives: Emerging Potential as Anti-Rheumatic Agents and other Pharmacological Effects [0.03%]
苯并噻唑衍生物作为抗风湿药物和其他药理作用的新兴潜力
Dhirendra Kumar,Divya Pathak,Smriti Gohri
Dhirendra Kumar
Benzothiazole derivatives are receiving considerable attention for their diverse pharmacological properties, particularly as anti-rheumatic agents. Rheumatoid arthritis is a common musculoskeletal disorder associated with chronic inflammati...
Design of pH-responsive Nanocarriers for Controlled Delivery of Anti-allergic Corticosteroid Analogues [0.03%]
pH响应纳米载体的制备及缓释抗过敏激素类药物研究
Sergey Gupalo,Sutha Devaraj,Kyaw Zaw Win et al.
Sergey Gupalo et al.
Introduction: Allergic inflammation has become an important public health issue. If left uncontrolled, it can lead to serious health problems. Mast cells and the drugs that regulate the endosomal compartments in these cel...
Antifungal Efficacy of Natural Oils: A Comprehensive Review on Mechanisms and Innovations [0.03%]
天然精油的抗真菌功效：关于机制和创新的全面综述
Piyush Jain,Shashikant Chandrakar,Pushpa Prasad Gupta
Piyush Jain
Introduction: Rising resistance to conventional antifungal agents, along with concerns over toxicity and environmental safety, has intensified the search for more sustainable and safer alternatives. Natural oils, particul...
Manu Sharma,Vibha Kumari,Meenakshi Bajpai
Manu Sharma
Introduction: Acne vulgaris is a common and complex skin condition characterised by excess oil production, blocked pores, and inflammatory lesions, such as papules and nodules. While hormonal factors and sebum overproduct...
Immunomodulatory Nanocarriers in Multiple Sclerosis: Dual Targeting of Microglia and Mitochondria for Precision Neurotherapy [0.03%]
纳米载体在多发性硬化症中的免疫调节作用：微胶质细胞和线粒体的双重靶向精准神经治疗
Ayushi Bhandari,Shikha Baghel Chauhan,Indu Singh et al.
Ayushi Bhandari et al.
The chronic neuroinflammatory and neurodegenerative disease known as Multiple Sclerosis (MS) is characterized by mitochondrial dysfunction and ongoing microglial activation. Developments in nanomedicine have enabled the design of immunomodu...
Integrated Virtual Screening Approaches to Identify Novel N- Substituted Heterocyclic Compounds as MAPK Inhibitors for Neuro Inflammation [0.03%]
整合虚拟筛选方法鉴定新型N取代杂环化合物作为MAPK抑制剂以治疗神经炎症
Aravind Kanniappan,Annapoorna Vadivelu
Aravind Kanniappan
Introduction: The Mitogen-Activated Protein Kinase (MAPK) is an intricately linked signaling cascade that frequently contributes to drug resistance in neurodegenerative diseases. This study presents an integrated approach...
Developing a Natural Oil-Based Organogel to Improve the Topical Delivery of Sertaconazole Nitrate [0.03%]
开发一种天然油基有机凝胶以改善硝酸塞拉康唑的局部给药效果
Piyush Jain,Shashikant Chandrakar,Pushpa Prasad Gupta et al.
Piyush Jain et al.
Objective: Conventional topical antifungal therapies often exhibit limited efficacy, poor patient adherence, and inadequate stability. To address these challenges, a microwave-assisted clove oil-based organogel of sertaco...
Polythiophene Nanocomposites as Smart and Sustainable Materials: Advancements in Energy, Environmental, and Biomedical Technologies [0.03%]
聚噻吩纳米复合材料作为智能和可持续材料在能源、环境和生物医学技术方面的进展
Shikha Baghel Chauhan,Indu Singh,Rohan et al.
Shikha Baghel Chauhan et al.
Polythiophene-based nanocomposites have emerged as a promising class of functional materials due to their tunable electrical conductivity, optical responsiveness, environmental stability, and structural versatility. This review presents a c...
Synthesis and Biological Activity of Guanidine Scaffold: A Comprehensive Review [0.03%]
胍类骨架的合成及生物活性研究综述
Surendra Kumar Verma,Shweta Singh Verma,Amit Verma et al.
Surendra Kumar Verma et al.
Derivatives of guanidine are found to be highly informative for their design in antibacterial and anticancer applications, thus positioning them as promising future drug candidates. This study evaluates and synthesizes a diverse group of gu...
Inhibition of Fenton Reaction-driven Lipid Peroxidation and Anti-inflammatory Activity of Extracts from Roots of Debregeasia Longifolia [0.03%]
德布雷加西亚长叶根提取物抑制芬顿反应驱动的脂质过氧化和抗炎活性研究
Faruk Alam,Moidul Islam Judder,Sumi Barman et al.
Faruk Alam et al.
Introduction: Debregeasia longifolia has been used traditionally in treating inflammatory and oxidative stress-associated disorders, but the potential of this herb in redox modulation has not been fully defined. Lipid per...