"Naringenin: A Promising Immunomodulator for Anti-Inflammatory, Neuroprotective, and Anti-Cancer Applications" [0.03%]
"萘酚素：一种有前景的免疫调节剂，可用于抗炎、神经保护和抗癌应用"
Sarita Solanki,Himangi Vig,Nidhi Khatri et al.
Sarita Solanki et al.
Background: Inflammatory, immune, and neurodegenerative diseases constitute a category of persistent and debilitating conditions affecting millions worldwide, with inter-twined pathophysiological pathways. Recent research...
Formulation and Characterization of Emulgel Lornoxicam Containing Lemon Grass Oil as Penetration Enhancer [0.03%]
含柠檬草油作为透皮吸收促进剂的洛尼昔康Emulgel制剂及特征研究
Vibha Kumari,Meenakshi Bajpai
Vibha Kumari
Introduction: Emulgel dosage form is an advanced form of transdermal drug delivery. It is a combination of emulsion and gel in a definite ratio. Emulsions are incorporated into the gel with proper mixing. The emulsion pre...
Evaluation of Spirooxindole-3,3'-pyrrolines-incorporating Isoquinoline Motif as Antitumor, Anti-inflammatory, Antibacterial, Antifungal, and Antioxidant Agents [0.03%]
评估含螺氧吲哚-3,3'-吡咯烷异喹啉结构单元的抗肿瘤、抗炎、抗菌、抗真菌和抗氧化剂性能
Areej M Jaber,Jalal A Zahra,Mustafa M El-Abadelah et al.
Areej M Jaber et al.
Background: A series of novel 2-(isoquinolin-1-yl)-spiro[oxindole-3,3'-pyrrolines] were synthesized by a one-pot three-component reaction involving dimethyl acetylenedicarboxylate, 3-phenylimidazo[5,1-a]isoquinoline and N...
Potential of Natural Products as Therapeutic Agents for Inflammatory Diseases [0.03%]
天然产物作为炎症性疾病治疗剂的潜力
Chintan Aundhia,Ghanshyam Parmar,Chitrali Talele et al.
Chintan Aundhia et al.
Inflammation is a complex biological response that plays a pivotal role in various pathological conditions, including inflammatory diseases. The search for effective therapeutic agents has led researchers to explore natural products due to ...
Novel Dual COX-2/5-LOX Inhibitory Activity by Chalcone Derivatives: A Safe and Efficacious Anti-Inflammatory Agent [0.03%]
一种新型的双COX-2 / 5-LOX抑制剂活性的查尔酮衍生物：安全有效的抗炎剂
Roopal Mittal,Shailesh Sharma,Amit Mittal et al.
Roopal Mittal et al.
Background: Non-communicable diseases are chronic systemic inflammation in humans that occurs because of enhanced inflammatory mediators of the arachidonic acid cas-cade. We aimed to explore whether the lead chalcone comp...
Pyrazoles as Anti-inflammatory and Analgesic Agents: In-vivo and In-silico Studies [0.03%]
吡唑类抗炎和止痛药物的体内及计算机辅助研究
Geeta Chahal,Jyoti Monga,Isha Rani et al.
Geeta Chahal et al.
Background: Pyrazole is a well-known nucleus in the pharmacy field with a wide range of other activities in addition to anti-inflammatory and analgesic, i.e., anticonvulsant, antiviral, and anticancer activities. There ar...
Flavonoids as Potential Natural Compounds for the Prevention and Treatment of Eczema [0.03%]
黄酮类化合物作为预防和治疗特应性皮炎的潜在天然物质
Javed Khan,Shikha Yadav,Divya Bhardwaj et al.
Javed Khan et al.
Eczema is a systemic autoimmune disease characterized by inflammation and skin manifestation with a range of comorbidities that include physical and psychological disorders. Despite recent advancements in understanding the mechanisms involv...
Decades Long Involvement of THP-1 Cells as a Model for Macrophage Research: A Comprehensive Review [0.03%]
THP-1细胞作为巨噬细胞研究模型的长期应用及其在巨噬细胞研究中的综合应用评价
Prakhar Sharma,Kaliyamurthi Venkatachalam,Ambika Binesh
Prakhar Sharma
Over the years, researchers have endeavored to identify dependable and reproducible in vitro models for examining macrophage behavior under controlled conditions. The THP-1 cell line has become a significant and widely employed tool in macr...
Immunoregulatory Effects of the Active Form of Vitamin D (Calcitriol), Individually and in Combination with Curcumin, on Peripheral Blood Mononuclear Cells (PBMCs) of Multiple Sclerosis (MS) Patients [0.03%]
活性维生素D（钙三醇）及其与姜黄素联用对多发性硬化症患者外周血单个核细胞的免疫调节作用
Mahdieh Fasihi,Mahsa Samimi-Badabi,Behrouz Robat-Jazi et al.
Mahdieh Fasihi et al.
Objectives: Multiple sclerosis (MS) is a chronic autoimmune inflammatory disease affecting the central nervous system. Immune cell subsets, notably T helper (Th) 17 and Th1, exert important roles in MS pathogenesis. Where...
Aarti Rajput,Rishabh Gaur,Mayank Kulshreshtha et al.
Aarti Rajput et al.
Background: Emulgel combines the qualities of an emulsion with those of a gel. In order to create an emulgel w/o or o/w, emulsions have to be formulated, which are then combined with a gelling agent, resulting in a dual-c...