Novel Mouth Rinse Displaying Analgesic and Anti-inflammatory Properties: An in vitro Study [0.03%]
一种具有镇痛和抗炎特性的新型漱口水：体外研究
Saravanan Sampoornam Pape Reddy,Delfin Lovelina Francis,Soumi Mondal et al.
Saravanan Sampoornam Pape Reddy et al.
Introduction: Periodontitis is a chronic inflammatory disease requiring effective anti-inflammatory treatments. Nano-silver and essential oils have shown potential due to their antimicrobial and anti-inflammatory properti...
Inclusive Drug Designing of Novel Indole Derivatives using Rationale, Pharmacophore Mapping and Molecular Docking [0.03%]
基于合理性、药效团映射和分子对接的新型吲哚衍生物药物设计及合成
Anuradha Mehra,Amit Mittal,Rahul Sharma et al.
Anuradha Mehra et al.
Introductions/Background: The presence of insufficient insulin signaling in type 2 diabetes arises due to either insulin resistance or impaired insulin secretion, ultimately lead-ing to elevated blood glucose levels, a condition known as hy...
Metabolic Evaluation of a Novel Hydroxyfuranone Compound: Adiposity Reduction in Obese Mice by Increasing SIRT1 Gene Expression [0.03%]
新型羟基呋喃酮化合物的代谢评估：通过增加肥胖小鼠SIRT1基因表达减少脂肪蓄积
Daniel Silva Moraes,Suely Rodrigues Pereira,Tulio Duque Esteves et al.
Daniel Silva Moraes et al.
Background: Obesity is one of the main health problems worldwide and is associated with type 2 diabetes mellitus. In this context, butenolides and sulfonamides are known for their anti-obesity effects. ...
In vitro Evaluation of the Synergistic Anti-inflammatory Activities of the Combined Hydroalcoholic Extracts from Mentha Pulegium L. and Pimpinella Anisum L [0.03%]
薄荷和茴香乙醇提取物的体外协同抗炎活性评估
Amina Tabet Zatla,Amina Hammoudi,Mohammed El Amine Dib et al.
Amina Tabet Zatla et al.
Background: Chronic inflammatory diseases are rising, driving the search for effective natural treatments. Mentha pulegium L. and Pimpinella anisum L. (anise) exhibit notable anti-inflammatory properties individually, but...
Leveraging Underutilized Sri Lankan Fruits in the Fight against Autoimmune Disorders [0.03%]
利用斯里兰卡未充分利用的水果对抗自身免疫疾病
M P Theja Virajini,Mithila Bandara,Prasad Jayasooriya et al.
M P Theja Virajini et al.
The potential of underutilized plant species to improve food security, health, eco-nomic output, and the environment has not been fully realized. Sri Lanka an island on the Indian Ocean is home to numerous plant species with significant med...
Toxicity and anti-inflammatory effects of Eleutherine bulbosa (Miller) Urb, ethanolic extract, in zebrafish (Danio rerio) [0.03%]
仙茅球茎的毒性及抗炎作用在斑马鱼中的研究
Dionisia P Ferreira,Fabrício H Holanda,Swanny F Borges et al.
Dionisia P Ferreira et al.
Introduction: Eleutherine bulbosa (Miller) Urb, popularly known as "marupa-zinho", is frequently used in traditional medicine for treating various diseases, including hypertension, ulcers, constipation, and intestinal inf...
Formulation, Characterization, and Cytotoxic Effect of Indomethacin-Loaded Nanoparticles [0.03%]
布洛芬载药纳米粒的制备、表征及体外细胞毒性实验
Kaan Yalçınkaya,Behiye Şenel,Evrim Akyıl
Kaan Yalçınkaya
Background: Indomethacin (IND), classified as class 2 in the Biopharmaceutical Classification System (BCS), has emerged as an anti-inflammatory agent with low solubility and high permeability. Widely used in the treatment...
In-vitro Antioxidant, and In-vivo Analgesics and Anti-inflammatory Activity of Allamanda blanchetii Leaf Extract in Rats [0.03%]
全叶提取物的体外抗氧化活性及在大鼠体内镇痛抗炎作用
Achla Vyas,Revathi Gupta,Rakesh Jatav
Achla Vyas
Objective: This study assessed the In-vitro Antioxidant and In-vivo Analgesics and Anti-inflammatory Activity of Allamanda blanchetii Leaf Extract in Rats. ...
Discovery and Chemical Exploration of Spiro[Benzofuran-3,3'-Pyrroles] Derivatives as Innovative FLT3 Inhibitors for Targeting Acute Myeloid Leukemia [0.03%]
作为新型FLT3抑制剂的苯并呋喃Spiro环[苯并呋喃-3,3'-吡咯]衍生物在治疗急性髓系白血病中的发现及其化学探索
Mohammed M Al-Mahadeen,Areej M Jaber,Jalal A Zahra et al.
Mohammed M Al-Mahadeen et al.
Aims: This study aimed at the synthesis of several spiro[benzofuran-3,3'-pyrroles] derivatives by a three-component reaction conducted by mixing DMAD, N-bridgehead het-erocycles, and benzofuran-2,3-diones in dichlorometha...
Genistein Enhances the Beneficial Effects of Exercise on Antioxidant and Anti-Inflammatory Balance and Cardiomyopathy in Ovariectomized Diabetic Rats [0.03%]
大豆异黄酮增强锻炼对卵巢切除糖尿病大鼠抗氧化抗炎平衡和心肌病的有益作用
Mohammad Mohammadi,Amir Mohammad Salehi,Samaneh Mohassel Azadi et al.
Mohammad Mohammadi et al.
Aims: This study aimed to investigate the effects of genistein, swimming exercise, and their co-treatment on heart oxidative stress, inflammation, and cardiomyopathy in ovariectomized diabetic rats. ...