Inhibition of Fenton Reaction-driven Lipid Peroxidation and Anti-inflammatory Activity of Extracts from Roots of Debregeasia Longifolia [0.03%]
德布雷加西亚长叶根提取物抑制芬顿反应驱动的脂质过氧化和抗炎活性研究
Faruk Alam,Moidul Islam Judder,Sumi Barman et al.
Faruk Alam et al.
Introduction: Debregeasia longifolia has been used traditionally in treating inflammatory and oxidative stress-associated disorders, but the potential of this herb in redox modulation has not been fully defined. Lipid per...
Anti-inflammatory Potential of Pongamia pinnata: A Comprehensive Review on Molecular Mechanisms and Therapeutic Implications [0.03%]
印度槐indi科植物的抗炎潜力：分子机制和治疗意义的全面回顾
Bhumika Dudhatra,Kashyap Thummar,Jigna Vadalia et al.
Bhumika Dudhatra et al.
Pongamia pinnata (L.) has long been used in both the Ayurvedic and Siddha systems of medicine. It belongs to the leguminous family and shows significant potential for antiinflammatory activity, further supported by growing pharmacological a...
Claudiu T Supuran
Claudiu T Supuran
Rajarshi Nath,Bikram Nandi,Arindam Maity et al.
Rajarshi Nath et al.
Inflammation is a defensive mechanism in the pathophysiology of many chronic diseases, including cancer, gastrointestinal problems, arthritis, cardiovascular disease, chronic wounds, and lesions, which may lead to death worldwide. Research ...
The Structural Analogy of MASP-2 with Thrombin and MASP-1 Reveals Strong Binding with PAR4 [0.03%]
MASP-2与凝血酶和MASP-1的结构类比显示可与PAR4强结合
Uzma Saqib,Mridul Madhuri,Sumati Hajela et al.
Uzma Saqib et al.
Introduction: The historical discovery that thrombin activates Protease-Activated Receptor 4 (PAR4) has paved the way for several novel findings. Besides thrombin, the complement lectin pathway protease Mannose-Binding Le...
Clinical Applications of Ligand Traps Targeting Activin Type II Receptors [0.03%]
靶向激活素II型受体的配体陷阱的临床应用
Kunihiro Tsuchida
Kunihiro Tsuchida
This review summarizes recent advances in ligand trap therapies targeting activin type II receptors [ActRIIA/ACVR2A and ActRIIB/ACVR2B], which serve as shared receptors for members of the TGF-β family, including activins, GDF11, and myosta...
Design, Spectral Insights, and Enhanced Antioxidant Potential of Novel Phenothiazine Derivatives-1 [0.03%]
新型吩噻嗪衍生物的设计、光谱学见解及增强的抗氧化潜力-1
Shamsher Singh,Himanchal Sharma,Smiriti Gohri et al.
Shamsher Singh et al.
Introduction: Phenothiazine derivatives represent an important class of heterocyclic compounds known for a wide range of pharmacological activities. Their antioxidant potential has drawn considerable interest for therapeu...
Visfatin as a Potential Inflammatory Biomarker and Therapeutic Target in Osteoarthritis: A Narrative Review [0.03%]
趋化因子visfatin作为炎症生物标志物和骨关节炎治疗靶点的潜力：综述性研究
Utpal Bhui,Ashutosh Sengar,Bimlesh Kumar et al.
Utpal Bhui et al.
Osteoarthritis (OA) is a common, chronic degenerative joint disease that leads to the progressive degeneration of articular cartilage, subchondral bone, and synovium. In short, it is characterized primarily by inflammation, cartilage breakd...
Next-Generation Probiotics in Allergy Therapy: Scientific Evidence and Clinical Applications [0.03%]
益生菌在过敏治疗中的科学证据及临床应用展望
Vatan Chaudhary,Atul Pratap Singh,Himanchal Sharma et al.
Vatan Chaudhary et al.
The global increase in allergic diseases, such as atopic dermatitis, allergic rhinitis, asthma, and food allergies, has become a major public health issue. These diseases typically involve immune dysregulation, including a Th1/Th2 imbalance...
Microsponge Drug Delivery Systems: Advancing the Therapeutic Efficacy of Anti-Inflammatory Medications [0.03%]
微载体递药系统在抗炎药物中的应用进展
Akshay Kumar,Rakesh,Rajesh Gautam et al.
Akshay Kumar et al.
Microsponge drug delivery systems represent an innovative approach to enhancing the therapeutic efficacy of anti-inflammatory drugs through controlled release, improved bioavailability, and targeted delivery. These porous polymeric microsph...