Synergistic Anticancer and Antibacterial Activities of Marine Sponge Extracts Combined with Fungal-Synthesized Silver Nanoparticles from Aspergillus flavus [0.03%]
由曲霉合成的银纳米颗粒结合海洋海绵提取物的协同抗癌和抗菌活性
Moath Alqaraleh,Ali Al-Samydai,Simone Carradori et al.
Moath Alqaraleh et al.
Introduction: This study explores the cytotoxic efficacy of combining Dysidea tuapokere or Agelas conifera extract with silver nanoparticles (AgNPs) synthesized from Aspergillus flavus on various cancer cell lines and pat...
Photoactivated Aluminium Phthalocyanine Drives Oxidative Stress and Apoptosis in Human Oesophageal Cancer Stem Cells [0.03%]
光活化铝酞菁通过氧化应激和凋亡作用于人食管癌干细胞
Onyisi Christiana Didamson,Heidi Abrahamse
Onyisi Christiana Didamson
Introduction: Photodynamic therapy (PDT), a light-based treatment strategy, has demonstrated efficiency against several cancers. However, the therapeutic effect of aluminium phthalocyanine chloride tetrasulfonate (AlPcS4C...
A Study of iNOS and PCNA Expression on the Aggressiveness of Oral Squamous Cell Carcinoma (OSCC) [0.03%]
iNOS和PCNA在口腔鳞癌侵袭性中的表达研究
Ahmed Noaman Ali,Mohamed Hamdy Sayed,Waleed Mohamed Shaker et al.
Ahmed Noaman Ali et al.
Introduction/objective: Oral Squamous Cell Carcinoma (OSCC) is one of the world's most aggressive cancers. Large-scale NO generation is facilitated by Inducible Nitric Oxide Synthase (iNOS) in chronic inflammatory disease...
Network Pharmacology, Molecular Docking, and Wnt Signaling-Associated Gene Expression Modulation Effects of New Anti-Colorectal Cancer Agents [0.03%]
网络药理学、分子对接及诱导Wnt信号通路相关基因表达调控的新抗结直肠癌活性成分的筛选与评价研究
Manikandan Alagumuthu,Ramprasath Rajavel,Sagufta Patel
Manikandan Alagumuthu
Introduction: Colorectal Cancer (CRC) remains a major global health challenge due to the emergence of resistance to current therapies. Identifying selective compounds that effectively trigger apoptosis in cancer cells whi...
Computational Design, Synthesis, and In Vitro Evaluation of Novel Piperazine-Based HDAC Inhibitors as Potential Breast Cancer Therapeutics [0.03%]
基于计算的新型哌嗪类组蛋白脱乙酰基酶抑制剂的设计、合成及体外评价作为潜在的乳腺癌治疗药物
Sehija Dizdarevic,Dusan Ruzic,Tatjana Srdic-Radic et al.
Sehija Dizdarevic et al.
Introduction: Limited treatment options and poor prognosis create a need for new therapies for triplenegative breast cancer. Modulating lysine acetylation of histone and non-histone proteins via histone deacetylase inhibi...
Emerging Frontiers in Prostate Cancer Diagnostics: Nanolaser-Guided Nanotechnology and Computational Biology for Biomarker Surveillance [0.03%]
前列腺癌诊断新 frontier：纳米激光引导的纳米技术及计算生物学在生物标志物监测中的应用
Shikha Baghel Chauhan,Indu Singh,Yash Kalra et al.
Shikha Baghel Chauhan et al.
Introduction: Prostate cancer remains a leading cause of cancer-related mortality in men, with early and accurate diagnosis being crucial for effective management. This review explores the convergence of nanolaser- assist...
Role of Cellular Senescence in Melanoma: Implications for Tumor Progression and Therapy [0.03%]
细胞衰老在黑色素瘤中的作用：对肿瘤进展和治疗的影响
Huixin Pan,Jinliang Jiang,Jing Zhang et al.
Huixin Pan et al.
Introduction: Aging is the most significant risk factor for cancer, with melanoma incidence and mortality rising with advancing age. Cellular senescence, a hallmark of aging, plays dual roles in melanoma progression, exer...
Development and Characterization of PEGylated β-Carotene-Loaded Liposomes as Radiosensitizers in HepG2 Hepatocellular Carcinoma Cells: In Vitro and In Silico Studies [0.03%]
PEG修饰的β-胡萝卜素载药脂质体作为放射增敏剂的制备及其在HepG2肝癌细胞中应用的体外和分子对接研究
Habiba Abdel-Moamen,Eman R Abbase,Manal F El-Khadragy et al.
Habiba Abdel-Moamen et al.
Introduction: Hepatocellular Carcinoma (HCC) is a leading cause of cancer death with limited responsiveness to radiotherapy. β-Carotene has chemopreventive properties, but its clinical use is hindered by poor aqueous sol...
Advancing in Acute Promyelocytic Leukemia Therapy Research: The Role of 3-Alkylpyridine Alkaloid Analogs in Overcoming Genetic and Molecular Barriers [0.03%]
急性早幼粒细胞白血病治疗研究进展：3-烷基吡啶生物碱类似物克服遗传及分子障碍的作用机制
Tulio R Freitas,Tâmara D de Almeida,Fernanda C G Evangelista et al.
Tulio R Freitas et al.
Introduction: Acute leukemias are malignant clonal disorders of blood cells, originating in the bone marrow. Acute Promyelocytic Leukemia (APL), when left untreated, progresses unfavorably, often resulting in severe hemor...
Morusin Attenuates Cancer Stemness and Modulates CSC-driven Macrophage Polarization in Cervical Cancer [0.03%]
桑色素通过抑制宫颈癌干细胞活性及调控CSC驱动的巨噬细胞极化发挥抗肿瘤作用
Tanya Tripathi,Udit Joshi,Apoorva Chaudhary et al.
Tanya Tripathi et al.
Introduction: Cancer stem cells (CSC) role in treatment resistance is well established. CSCs promote M2 macrophage polarization within the tumor microenvironment, creating a pro-tumorigenic feedback loop that sustains CSC...