Timosaponin A-III Induces ROS-mediated Apoptosis and Triggers Protective Autophagy via the AMPK/mTOR Pathway in Prostate Cancer [0.03%]
TIMOSAPONIN A-III通过AMPK/mTOR途径诱导前列腺癌细胞ROS介导的凋亡和保护性自噬
Jianjian Wu,Juntao Li,Qiang Guo et al.
Jianjian Wu et al.
Prostate cancer, timosaponin A‑III, apoptosis, autophagy, reactive oxygen species, AMPK/mTOR. Introduction: Timosaponin A-III (TAIII) is an effective ant...
Molecular Pathways and Biomarkers in Endometrial Carcinoma: Paving the Way for Precision Medicine [0.03%]
子宫癌的分子途径和生物标志物：为精准医疗铺平道路
Krishana Kumar Sharma,Swati Tamta,Mohit Pandey et al.
Krishana Kumar Sharma et al.
Endometrial carcinoma (EC) is one of the most prevalent gynecological malignancies, with an increasing incidence globally. This review explores the role of molecular markers in revolutionizing the diagnosis, prognosis, and management of EC....
The Hematological Variations and Effect of Cadmium Induced Toxicity on Mammary Tumors Development in Albino Mice. A Comparative Model Study on the Effect of Heavy Metals in Human Breast Cancer [0.03%]
cadmium对小白鼠乳腺肿瘤发生的影响及诱导毒性作用的血液学变化研究——重金属对人类乳腺癌影响比较模型研究
Saba Munir,Yasir Nawaz,Fouzia Tanvir et al.
Saba Munir et al.
Introduction: Breast cancer develops in breast tissues, in ducts and lobules. It affects both genders, though it is uncommon in men. Hematological variations are important considerations and deficiencies in metals can neg...
Serotonin Metabolism Shapes the Tumor Immune Microenvironment and Serves as a Therapeutic Target in Lung Cancer [0.03%]
血清素代谢重塑肺癌免疫微环境并可作为潜在治疗靶点
Miersalijiang Yasen,Naikun Sun,Jiude Jia et al.
Miersalijiang Yasen et al.
Introduction: Lung cancer progression involves complex interactions between metabolic pathways and the immune microenvironment. The role of serotonin, a tryptophan-derived metabolite, in immune responses to lung tumors re...
Retraction Notice to "The Natural Flavonoid Naringenin Inhibits the Cell Growth of Wilms Tumor in Children by Suppressing TLR4/NF-κB Signaling" [0.03%]
撤稿通知“黄酮类天然产物芸香素通过抑制TLR4/NF-κB信号转导抑制儿童肾母细胞瘤的生长”
Hongtao Li,Peng Chen,Lei Chen et al.
Hongtao Li et al.
The publisher has retracted the article "The Natural Flavonoid Naringenin Inhibits the Cell Growth of Wilms Tumor in Children by Suppressing TLR4/NF-κB Signaling," which was published in Anti-Cancer Agents in Medicinal Chemistry (https://w...
Anticancer Efficacy and Metabolomic Profiling of Punica granatum Leaf Extracts: In vitro and In silico Approaches [0.03%]
番石榴叶提取物的抗肿瘤效果及代谢组学特征：体外和分子模拟方法
Mital Kaneria,Kalpna Rakholiya,Disha Patel et al.
Mital Kaneria et al.
Introduction: Current research focuses on identifying and analyzing bioactive metabolites with significant therapeutic properties derived from Punic granatum L. (Pomegranate) leaves. ...
Bioinformatics And Experimental Insights Into Sotorasib Resistance Mechanisms in Non-small-cell Lung Cancer [0.03%]
非小细胞肺癌中sotorasib耐药机制的生物信息学和实验见解
Dongbing Li,Guizhen Lyu
Dongbing Li
Introduction: This study aims to identify the key genes and pathways associated with sotorasib resistance in Non-Small Cell Lung Cancer (NSCLC) using bioinformatics analyses and experimental validation, with a focus on un...
dHG-5 Exhibits Dual Efficacy of Anti-Metastatic and Anti-hypercoagulability in Mice by Inhibiting Heparanase and Intrinsic Coagulation Pathway [0.03%]
D HG-5通过抑制肝素酶和内在凝血途径在小鼠中表现出抗转移和抗高凝的双重疗效
Ziheng Tong,Zhipeng Xu,Wen Yang et al.
Ziheng Tong et al.
Introduction: Cancer metastasis and associated thrombosis are significant contributors to cancerrelated mortality, necessitating therapeutic strategies that simultaneously address both issues. This study aimed to evaluate...
A Comprehensive Overview of the Therapeutic Potential of Pyrimidine Analogues in the Management of Colorectal Cancer [0.03%]
嘧啶类似物在结直肠癌治疗中的潜力概述
Sathishkumar M,Dhunmati K,Ramalakshmi N et al.
Sathishkumar M et al.
Colorectal cancer is the fourth most prevalent cause of cancer-related fatalities, and cancer is still one of the major causes of death globally. Although pyrimidine analogues can target abnormal cellular growth, they have demonstrated pote...
The Potential of Next-generation Multi-functional Nanoplatforms for Breast Cancer [0.03%]
下一代多功能纳米平台在乳腺癌诊疗中的应用潜力
Shreya Gupta,Tanmay J Urs,Navya Aggarwal et al.
Shreya Gupta et al.
The next-generation nanoparticles overcome the drawbacks of early nanoplatforms by integrating multiple functions, such as drug delivery, controlled drug release, and combination therapy, into a single system. This study examines the biomed...