Rosmarinic Acid as a Potential Therapeutic Agent against Neuroblastoma: Anticancer Activity and Molecular Docking Insights [0.03%]
岩梗酸作为治疗神经母细胞瘤潜在药物的活性及分子机制研究
Pınar Yumrutaş,Demet Taşdemir,Önder Yumrutaş
Pınar Yumrutaş
Introduction: Rosmarinic acid (RA) is a phenolic acid known for its important biological activities. Although it has been shown to inhibit various cancer cell types, its effects on the suppression and induction of apoptos...
A Review of the Anticancer Properties of Cedrol and its Molecular Mechanisms [0.03%]
雪松醇的抗肿瘤性质及其分子机制研究进展
Ali Mohammad Pourbagher Shahri,Sajad Sahab Negah,Meysam Moghbeli et al.
Ali Mohammad Pourbagher Shahri et al.
Despite decades of research on promising new therapies, cancer remains a leading cause of morbidity and mortality. Over the years, extensive research has been conducted on the potential anticancer effects of various medicinal plants. One ex...
Targeting the Lin28/let-7 Axis with Compounds to Regulate Transcriptional Control in Cancer [0.03%]
靶向Lin28/LET-7轴的化合物通过调节癌症中的转录控制发挥作用
Xingpeng Wang,Pham Kim Thuong Van,Bo Liu et al.
Xingpeng Wang et al.
Lin28 is a pivotal RNA-binding protein that regulates the biogenesis of let-7 microRNAs, which play a crucial role in the post-transcriptional regulation of oncogenes in cancer. The Lin28/let-7 axis is integral to the regulation of key cell...
Simone Carradori
Simone Carradori
João A L de Lima,Lídia Moreira Lima
João A L de Lima
Isocitrate Dehydrogenases (IDH) are ubiquitous enzymes essential for cellular metabolism, including the Krebs cycle, glutamine metabolism, lipogenesis, and redox balance. Mutations in IDH1 and IDH2 are implicated in several tumors - gliomas...
Retraction Notice to "Anti-proliferative, Morphological and Molecular Docking Studies of New Thiophene Derivatives and their Strategy in Ionic Liquids Immobilized Reactions" [0.03%]
有关“噻吩衍生物的抗增殖、形态和分子对接研究及离子液体固载反应中的应用策略”的撤稿声明
Rafat M Mohareb,Sayeed Mukhtar,Humaira Parveen et al.
Rafat M Mohareb et al.
We regret to inform you that the article titled "Anti-proliferative, Morphological and Molecular Docking Studies of New Thiophene Derivatives and their Strategy in Ionic Liquids Immobilized Reactions," published in Volume 24, Issue 9, 2024 ...
Targeting WWPI HECT Domain by Small Inhibitors for Restoring PTEN Tumor Suppressive Role in Glioblastoma Therapy [0.03%]
靶向WWP1的HECT结构域的小分子抑制剂可恢复PTEN在胶质母细胞瘤治疗中的抑癌作用
Atta Ullah,Majid Khan,Sadeeq Ur Rahman et al.
Atta Ullah et al.
Introduction: PTEN (Phosphatase and tensin homolog) is a valuable regulator of the PI3K-AKT and mTOR pathways and is frequently mutated in cancer-like glioblastoma. The WWPI HECT domain has a group of enzymes called E3 li...
Unveiling the Distinct Effects of a Two-Dimensional Copper/Sodium Complex: Oxidative Stress on Erythrocytes and Cytotoxicity, Apoptosis, Drug Resistance, and Inflammation in Lung Cancer Cells [0.03%]
二维铜/钠复杂化合物的抗氧化应激、细胞毒性和凋亡作用：对红血球和肺癌细胞的影响研究
Chenchen Li,Mostafa Heidari Majd,Ameneh Heidari et al.
Chenchen Li et al.
Introduction: Copper complexes, as endogenous metals, have potential in cancer therapy, addressing issues associated with cisplatin. Since cisplatin uses Copper Transporter 1 (CTR1) for cellular entry, copper complexes ma...
Luteolin Enhances Anticancer Effects of PX-478 during Hypoxic Response in Metastatic Breast Cancer Cells [0.03%]
染料木素通过影响低氧响应增强PX-478对转移性乳腺癌细胞的抗癌作用
Muzaffer Dukel,Fatema Zarzou
Muzaffer Dukel
Introduction: The presence of severe hypoxic stress can drive tumor growth, angiogenesis, and metastatic characteristics via up-regulated hypoxia-inducible factor 1-alpha (HIF-1α). Hence, targeting HIF-1α is considered ...
The Promising Role of PKM2 in the Diagnosis and Prognosis of Ovarian Cancer [0.03%]
PKM2在卵巢癌诊断和预后中的作用不容小觑
Praveen Kumar Borra,Phool Chandra,Himanshu Sharma et al.
Praveen Kumar Borra et al.
PKM2 has emerged as a critical biomarker with the potential to enhance both diagnostic accuracy and therapeutic strategies in ovarian cancer. Due to its high fatality rate and difficulty identifying early signs, ovarian cancer remains a maj...