Camel Milk in Skin Cancer Therapeutics: An In-vitro and In-vivo Study [0.03%]
骆驼奶在皮肤癌治疗中的作用：一项体外和体内研究
Neha Jain,Lavina Bagoria,Sneha Keelka et al.
Neha Jain et al.
Introduction: Therapeutic applications of camel milk in various human ailments have led to the investigation of camel milk against multiple cancers. However, the absence of its scientific evidence in skin cancer protectio...
Jianpi Yiwei Granules for Chemotherapy-Induced Gastrointestinal Reactions: A Randomized Double-Blind Placebo-Controlled Trial [0.03%]
健脾益胃颗粒治疗化疗所致胃肠反应的随机双盲安慰剂对照试验
Kerun Cai,Jiayang Chen,Nuo Li et al.
Kerun Cai et al.
Introduction: Chemotherapy-induced gastrointestinal reactions are common in non-small cell lung cancer (NSCLC) patients undergoing carboplatin-based chemotherapy. Jianpi Yiwei granules (JPYW), a traditional Chinese medici...
The EP300-Targeting Drug CCS1477 Inhibits the Growth and Development of Diffuse Large B-Cell Lymphoma by Promoting Apoptosis and Mitophagy to Reduce Drug Resistance [0.03%]
靶向EP300药物CCS1477通过促进凋亡和线粒体自噬来减少耐药以抑制弥漫性大B细胞淋巴瘤的生长和发展
Rujia Si,Yihan Zhang,Bowen Hu et al.
Rujia Si et al.
Introduction: Approximately 30% of patients with diffuse large B-cell lymphoma (DLBCL) develop primary resistance or relapse, owing to the high heterogeneity and aggressive nature of the disease. Consequently, novel drugs...
Targeting Telomere Shelterin Protein TPP1 with Elbasvir: Induction of Autophagy and Suppression of Esophageal Cancer Tumorigenesis [0.03%]
靶向作用于端粒保护蛋白TPP1的Elbasvir：诱导自噬并抑制食管癌肿瘤发生
Maoju Tang,Miyuan Yang,Jiling Wen et al.
Maoju Tang et al.
Introduction: Esophageal cancer often develops insidiously, with most cases diagnosed at an advanced stage. Currently, the pathogenesis of esophageal cancer remains unclear, treatment outcomes are poor, and the five-year ...
GPR65 as a Laryngeal Cancer Risk Gene Identified through Single-Cell Transcriptomics, Mendelian Randomization Analysis, and Experimental Validation [0.03%]
通过单细胞转录组学、孟德尔随机化分析和实验验证鉴定出的喉癌风险基因GPR65
Qing-Jie Mao,Ya-Quan Zhou,Bing-Shuang Zhao et al.
Qing-Jie Mao et al.
Introduction: Laryngeal cancer is a common malignant tumor of the head and neck worldwide. This study aimed to identify potential risk genes, with a particular focus on GPR65, and to investigate its functional mechanism i...
Annoor Awadasseid,Mengda Wu,Feng Zhang et al.
Annoor Awadasseid et al.
Introduction: The emergence of immune checkpoint inhibitors has revolutionized the treatment of cancer. Among these, the programmed cell death protein-1 (PD-1)/programmed death-ligand 1 (PD-L1) axis remains a critical tar...
Targeting TGF-βR1 Signaling Pathway in Pancreatic Cancer: A Potential Approach with Synthetic Flavanols [0.03%]
靶向转化生长因子-β受体1信号通路治疗胰腺癌：合成黄烷醇的潜在方法
Rachel Cordeiro,Milind Bhitre,Shivam Varma et al.
Rachel Cordeiro et al.
Introduction: Pancreatic adenocarcinoma is a highly aggressive cancer with a poor prognosis and a five-year survival rate of just 13%. Its asymptomatic onset, rapid progression, and resistance to therapy make it challengi...
Induction of Apoptosis and Activation of Endoplasmic Reticulum Stress by SJ6986 in Diffuse Large B-cell Lymphoma [0.03%]
SJ6986诱导弥漫性大B细胞淋巴瘤凋亡及内质网应激的活化
Chenxing Zhang,Bangxue Jiang,Xiaomei Liang et al.
Chenxing Zhang et al.
Introduction: Diffuse large B-cell lymphoma (DLBCL) is one of the most prevalent hematological malignancies with high mortality. G1 to S phase transition 1 (GSPT1), a key translation termination factor involved in protein...
PRR22: A Novel Prognostic Indicator and Therapeutic Target for Prostate Cancer [0.03%]
前列腺癌的新型预后指标和治疗靶点 PRR22
Wenxia Chen,Guodong Ding,Yuantang Zhong et al.
Wenxia Chen et al.
Introduction: Prostate cancer (PRAD) remains a leading malignancy with limited prognostic biomarkers and therapeutic targets. PRR22, a proline-rich protein-coding gene, has a role in PRAD that remains undefined. This stud...
Apoptosis-Mediated Anticancer Activity of Zinc Oxide Nanoparticles Derived and Characterized from Halophila beccarii [0.03%]
来源于海洋植物贝氏海团藻的锌纳米颗粒的抗肿瘤活性及作用机制研究
Jayasheela Sarilla,Vani Mathakala,Uma Maheswari Devi Palempalli
Jayasheela Sarilla
Introduction: Recent advancements in nanomedicine have drawn attention to the use of zinc oxide nanoparticles as apoptotic agents to address triple-negative breast cancer. Halophila beccarii-mediated zinc oxide nanopartic...