Artichoke Extract Ameliorates CCl4-Induced Hepatocellular Carcinoma in Albino Rats by Regulating the Phosphatidylinositol 3-kinase/serine-threonine Protein Kinase Pathway [0.03%]
洋蓟提取物通过调节磷脂酰肌醇-3激酶/蛋白丝裂原活化蛋白激酶途径改善CCl4诱导的白化大鼠肝细胞癌作用的研究
Nabila Zein,Fathy Ahmed Yassin,Maha M Rashad et al.
Nabila Zein et al.
Introduction: Cynara scolymus (Artichoke) is a medicinal plant of significant pharmacological importance, rich in phenolic acids and flavonoids. Therefore, the current research aimed to assess the anticancer properties an...
Drug Release, Entrapment Efficacy, and Drug Loading Capacity of Taxanes Loaded Solid Lipid Nanoparticles (SLNs) [0.03%]
紫杉烷类药物包载于固脂纳米颗粒(SLNs)中的体外释放、有效负载及包封率研究
Hadi Valizadeh,Gity Mirzaei,Allahveirdy Arjmand et al.
Hadi Valizadeh et al.
Background: Solid lipid nanoparticles (SLNs) are submicron carriers with great promise in revolutionizing cancer therapy. They offer a potential solution to the side effects of conventional anticancer drugs, such as syste...
The Multi-pathway Mechanism and Co-delivery System of Oleanolic Acid Derivatives in Reversing Chemotherapy Resistance in Breast Cancer [0.03%]
齐墩果酸衍生物逆转乳腺癌耐药的多通路机制及共载输送体系研究
Kehong Yang,Yufang Li,Ying Zou et al.
Kehong Yang et al.
Breast cancer threatens the health of women worldwide. However, the use of chemotherapy for breast cancer is prone to generating side effects and drug resistance. Therefore, identifying natural compounds with anticancer activity is a better...
CD24 and Mutant p53: Emerging Therapeutic Targets in Prostate Cancer Progression [0.03%]
CD24和突变型p53：前列腺癌进展中的新兴治疗靶点
Yin Qinzhamusu,Lan Xintian,Gan Zhihao et al.
Yin Qinzhamusu et al.
Introduction: Prostate cancer is a leading cause of cancer-related mortality in men worldwide, and the treatment of metastatic castration-resistant prostate cancer (mCRPC) remains a major clinical challenge. CD24, a glyco...
A Systematic Review of the Mechanistic Effects of Ginsenosides on Enhancing Radiotherapy and Providing Radioprotection [0.03%]
人参皂苷改善放疗效果及防护的机制研究系统评价
Sepideh Abdi,Saeid Heidari-Soureshjani,Sahar Rostamian et al.
Sepideh Abdi et al.
Introduction/objective: Radiotherapy (RT) is a standard cancer treatment that may be associated with problems such as ineffectiveness and side effects. This study investigated ginsenosides' radiosensitizing and radioprote...
FN-1501 Synergistically Enhances Almonertinib Efficacy in EGFR-TKI-Resistant Lung Adenocarcinoma through Ferroptosis Induction [0.03%]
FN-1501通过诱导铁死亡协同增强艾美替尼对EGFR-TKI耐药肺腺癌的疗效
Sitong Feng,Chen Peng,Dan Zou et al.
Sitong Feng et al.
Introduction: The emergence of acquired resistance to Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors (EGFR-TKIs) presents a significant barrier to effective treatment in lung adenocarcinoma. This study invest...
Yihua Chen
Yihua Chen
ALG3 as a PanCancer Oncogene: Bioinformatics Analysis and Identification of Small-Molecule Inhibitors [0.03%]
ALG3作为泛癌症原癌基因的生物信息学分析及其小分子抑制剂的鉴定
Hesham M Hassan,Waleed K Abdulsahib,Hassan M Otifi et al.
Hesham M Hassan et al.
Introduction: Glycosylation plays a crucial role in cellular processes such as recognition and signaling, and its dysregulation is associated with tumor progression. Alpha-1,3-mannosyltransferase (ALG3) is a key enzyme in...
Metformin Inhibits the Growth of Hypopharyngeal Squamous Cell Carcinoma of Fadu Cell and Down-Regulates LncAROD to Improve Prognosis [0.03%]
二甲双胍通过抑制长链非编码RNA LncAROD发挥对下咽鳞癌Fadu细胞的增殖抑制作用并改善预后
Fang Liu,Huihui Xie,Meiyu Liu et al.
Fang Liu et al.
Background: Hypopharyngeal Squamous Cell Carcinoma(HSCC) is associated with a poor prognosis due to challenges in early detection, early metastasis, and limited treatment options. ...
Berberine Hydrochloride Inhibits the Proliferation and Tumorigenesis of Hepatocellular Carcinoma Cells by Regulating Amino Acid Metabolism [0.03%]
盐巴马汀通过调节氨基酸代谢抑制肝癌细胞增殖和成瘤性
Qipan Jian,Yuhang Shu,Zhenhui Li et al.
Qipan Jian et al.
Background: Hepatocellular carcinoma (HCC) is a frequent cancer in the world and a highly fatal primary liver cancer. Berberine hydrochloride (BBH) has exhibited therapeutic potential against HCC with no toxicity and good...