Photodynamic Versus Sonodynamic Therapy In Vitro: Antimicrobial Activity of Liposomal Rose Bengal [0.03%]
光动力学与声动力学疗法的对比研究：玫瑰花青脂质体的抗菌活性
Omar Molina-Alejandre,Norma Angélica Villanueva-Martínez,María Guadalupe Nava-Arzaluz et al.
Omar Molina-Alejandre et al.
Purpose: To compare the antimicrobial effect of Photodynamic (PT) and Sonodynamic Therapy (ST) applying Rose Bengal (RB) loaded in liposomes, intended for the treatment of skin infections. ...
Advances in Microneedle Technology for Targeted Therapy in Alzheimer's and Parkinson's Disease [0.03%]
用于阿尔茨海默病和帕金森病靶向治疗的微针技术进展
Neha Kanojia,Geeta Deswal,Ajmer Singh Grewal et al.
Neha Kanojia et al.
Introduction: The fourth major cause of death worldwide is Neurodegenerative Diseases (NDs), including Alzheimer's and Parkinson's disease. The existing therapies have only a small effect on alleviating symptoms, mainly b...
Synthesis, Characterization and Biological Evaluation of New Furo[2,3-b] pyridine Derivative: Molecular Docking, Antioxidant and Antimicrobial Activity Enhanced by Silver Nanoparticle Formulation [0.03%]
新型呋喃并吡啶衍生物的合成、表征及生物学评价：银纳米粒子配方增强的分子对接、抗氧化和抗菌活性研究
Menier Al-Anazi,Mohammad M Ibrahim,Abdullah Al-Fawwaz et al.
Menier Al-Anazi et al.
Introduction: Pyridine-based derivatives are well-known for their broad-spectrum therapeutic applications, particularly as antimicrobial and antioxidant agents. However, clinical utility is often hindered by poor aqueous ...
Therapeutic and Drug-Delivery Applications of Extracellular Vesicles in the Brain, Lung, and Liver [0.03%]
脑、肺和肝脏的细胞外囊泡治疗和药物递送应用
Rokgi Hong,Budjav Jadamba,Gyeongmin Jeong et al.
Rokgi Hong et al.
Extracellular vesicles (EVs), encompassing exosomes, microvesicles, and apoptotic bodies, are pivotal mediators of intercellular communication, facilitating the transfer of nucleic acids, proteins, and lipids between cells and thereby influ...
Brain Targeting via Nasal Delivery: Enhanced Docetaxel Delivery Using Mucoadhesive-Coated PLGA Nanoparticles [0.03%]
经鼻给药递脑：使用黏膜粘附型PLGA纳米粒增强多西他赛的传递
Ruba S Darweesh,Alaa Abu Dayah,Nusaiba K Al-Nemrawi et al.
Ruba S Darweesh et al.
Introduction: Brain cancer treatment is hindered by the complexity of the brain and the restrictive nature of the blood-brain barrier (BBB), which limits the efficacy of anticancer drugs. This study aimed to enhance the d...
Exosomes as Advanced Nanocarriers: Overcoming the Blood-Brain Barrier for Targeted Therapeutic Delivery in Neurodegenerative Diseases [0.03%]
外泌体作为先进的纳米载体：克服血脑屏障以实现神经退行性疾病靶向治疗递送
Farhang Aliakbari,Mehregan Rahmani,Kimia Marzookian et al.
Farhang Aliakbari et al.
Introduction: Exosomes, nanosized extracellular vesicles secreted by diverse cell types, have emerged as promising natural nanocarriers for therapeutic delivery. Their intrinsic ability to cross the Blood-Brain Barrier (B...
A pH/Enzyme Dual-Responsive Dropping Pill System for Colon-Targeted Delivery of Naringin [0.03%]
一种用于橘皮素结肠靶向输送的pH/酶双重响应滴丸系统
Xintao Qiu,Yuanyuan Chen,Jing Shu et al.
Xintao Qiu et al.
Introduction: Ulcerative colitis requires targeted therapy to enhance efficacy and minimize systemic side effects. This study aimed to address the low bioavailability and nonspecific release of naringin, a natural anti-in...
Nano Self-assembly of μ-Conotoxin CnIIIC with Enhanced Muscle Relaxation Effect [0.03%]
具有增强的肌肉松弛作用的μ-锥形毒肽CnIIIC的纳米自组装
Yiman Wu,Xiufang Ding,Qian Zhang et al.
Yiman Wu et al.
Introduction: Muscle relaxants are fundamental to modern anesthesia, primarily targeting voltage-gated sodium channels. While μ-conotoxin CnIIIC is a potent peptide inhibitor, its clinical translation is hindered by poor...
The Fabrication, Characterization, and Ulcerative Colitis Treatment of Colonic Targeting Microspheres Loading Baicalein Nanocrystals Based on the "Nano in Micro" Strategy [0.03%]
基于“纳米在微米中”的策略负载 baicalin 纳米晶体的结肠 targeting 微球的制备及溃疡性结肠炎治疗研究
Ziwei Li,Yiwen Hu,Xiaochao Huang et al.
Ziwei Li et al.
Introduction: Ulcerative colitis (UC) is a chronic inflammatory bowel disease with an increasing global incidence. Current clinical therapies are often limited by insufficient efficacy and adverse effects, highlighting th...
Synergistic Enhancement of Skin Whitening and Repair After Medical Aesthetics: A Triple Permeation System Combining Nanocarriers, Atomization, and Electro-Permeation Technology [0.03%]
结合纳米载体、雾化和电透技术的医美术后肤色亮肤修复三效渗透系统研究
Juntong Li,Dan Luo,Jun Deng et al.
Juntong Li et al.
Background: The majority of post-procedure skin whitening and repair methods for postmedical aesthetic procedures fail to achieve desired skin whitening and repair functionality due to limitations in stability and skin pe...