Kidneys Toxicity and Biodistribution of Albumin-Based Gold and Silver Nanoclusters [0.03%]
基于血清白蛋白的金、银纳米团簇的肾脏毒性及生物分布研究
Hussein Alhawari,Sameeha AlShelleh,Nisreen Abu Shahin et al.
Hussein Alhawari et al.
Background: The interaction of the kidneys with nanoparticles is a fundamental issue that accelerates the proper design of efficient and safe nanotherapeutics. The present study aimed to establish the kidney toxicity and ...
Combination of Luteolin and Silibinin Has Hepatoprotective Effects on Rats' Liver Fibrosis Induced by Thioacetamide [0.03%]
低剂量芹菜素联合异鼠李素对硫代乙酰胺致肝纤维化保护作用及机制研究
Zaenah Z Alamri,Rahaf F Aharthi,Sahar J Melebary
Zaenah Z Alamri
Introduction: A serious public health condition called liver fibrosis can cause cirrhosis, cancer, and even patient death. Method: This...
Biocompatibility Evaluation of a Dexamethasone Mucoadhesive Nanosystem: Preclinical and Preliminary Clinical Evaluations [0.03%]
地塞米松粘附性纳米系统生物相容性评价：前临床和初步临床研究
Graciela Lizeth Pérez-González,Luis Jesús Villarreal-Gómez,Lucia Margarita Valenzuela-Salas et al.
Graciela Lizeth Pérez-González et al.
Introduction: There is a strong need for drug delivery systems that are both highly compatible with biological tissues and effective when used in the oral mucosa. While gels, creams, or ointments are currently employed fo...
Optimizing Transdermal Drug Delivery with Novasome Nanocarriers: A Quality by Design (QbD) Framework [0.03%]
基于质量源于设计（QbD）框架的纳米载体 novasome 优化经皮给药体系
Prabhjot Kaur,Priyanka Kriplani
Prabhjot Kaur
A revolutionary encapsulation-based drug delivery technique called novasome technology outperforms conventional liposome systems in terms of effectiveness and efficiency. It is comprised of free fatty acid, cholesterol, and surfactant, whic...
Krishna Yadav,Ajazuddin,Mukesh Sharma et al.
Krishna Yadav et al.
The global burden of Chronic Liver Diseases (CLDs) is escalating, with increasing prevalence and mortality. Various conditions ranging from fibrosis, cirrhosis, and hepatocellular carcinoma are associated with conditions such as toxin accum...
Novel Antibiotic-Loaded PEGylated Xerogels of Acidified Chitosan for Periodontal Diseases [0.03%]
用于牙周疾病的新型抗生素负载的接枝PEG酸性壳聚漠干凝胶
Farjad Zafar,Muhammad Ali Sheraz,Syed Abid Ali et al.
Farjad Zafar et al.
Objectives: The primary aim of this study was to develop an effective treatment strategy for periodontal diseases that maximizes therapeutic effects while minimizing systemic adverse effects. Specifically, the study focus...
Lactoferrin-Conjugated Nanocarriers for Transformative Strategies in Cancer Management: New Insights on Breast Cancer Therapy [0.03%]
乳铁蛋白修饰的纳米载体在癌症管理中的变革策略：对乳腺癌治疗的新见解
Rakesh Pahwa,Sanskriti Saini,Gulshan Sharma et al.
Rakesh Pahwa et al.
Cancer represents a diverse and complex spectrum of diseases characterized by the abnormal growth and proliferation of cells, establishing a formidable global health challenge. Within the array of diverse cancers, breast cancer arises as on...
Spray-Dried Inhalable Favipiravir Dry Powder Formulation for Influenza Therapy: Preparation and In vivo Evaluation [0.03%]
用于流感治疗的喷雾干燥吸入型法匹拉韦干粉制剂：制备及其体内评价
Xinyu Zhang,Baogang Wang,Likun Xu et al.
Xinyu Zhang et al.
Background: Influenza, a seasonal infectious disease, has consistently posed a formidable challenge to global health in recent years. Favipiravir, an RNA-dependent RNA polymerase inhibitor, serves as an anti-influenza med...
Biomimetic Brain-Targeted Drug Delivery System for the Treatment of Brain Diseases [0.03%]
仿生脑靶向药物传输系统在脑疾病治疗中的应用
Yaomin Tan,Ziyan Tang,Yizhi Zhang et al.
Yaomin Tan et al.
The blood-brain barrier (BBB) effectively blocks most drugs from entering the central nervous system, posing significant challenges to the treatment of brain diseases, such as cerebrovascular disorders, neurodegenerative conditions, and bra...
Advancements and Challenges of Plant-derived Extracellular Vesicles in Anti-Cancer Strategies and Drug Delivery [0.03%]
植物源细胞外囊泡在抗癌策略和药物递送中的进展与挑战
Fen Zhang,Xiao Liang,Hao Liu et al.
Fen Zhang et al.
Background: Plant-derived extracellular vesicles (PDEVs) are vital for intercellular material exchange and information transfer. They significantly regulate cellular functions, tissue repair, and self-defense mechanisms. ...