Synthesis, Characterization, In vitro and In vivo Evaluation of Pullulan-co-MAA Hydrogels Decorated with 5-fluorouracil for Oral-Colonic Delivery [0.03%]
一种用于口腔结肠递送的5-氟尿嘧啶修饰的普鲁兰-马来酸酐共聚物水凝胶的制备及体内外评价研究
Iqra Islam,Kaleem Ullah,Shujaat Ali Khan et al.
Iqra Islam et al.
Introduction: Conventional treatment of colorectal cancer causes severe side effects, leading to non-compliance. Hydrogels are polymer-based oral drug delivery carriers that offer numerous advantages. ...
Advancements in 3D Printing and Nanomaterials for Personalized Drug Delivery [0.03%]
个性化药物输送的3D打印和纳米材料进展
M Arjun Gokulan,J Narayanan
M Arjun Gokulan
3D printing, also known as additive manufacturing, has transformed drug delivery by enabling the development of complex, patient-specific dosage forms and implantable systems tailored to individual therapeutic needs. This review explores th...
Utilizing Extracellular Vesicles for Delivering Therapies in Neurodegenerative Disorders [0.03%]
利用细胞外囊泡治疗神经退行性疾病
Ashish Dilip Sutar,Anuja Shashikant Kamble,Nitin Chitranshi et al.
Ashish Dilip Sutar et al.
Neurodegenerative diseases (NDs) are characterized by slow progression and late detection, seriously compromising the efficiency of treatments. The presence of the blood-brain barrier (BBB) significantly impairs conventional therapies. More...
Mesoporous Silica Nanoparticles with Dual Function of Anti-Inflammatory and Lubrication for Rheumatoid Arthritis Treatment [0.03%]
具有抗炎和润滑双重功能的用于治疗类风湿性关节炎的介孔二氧化硅纳米粒子
Hao Zhou,Ying Zeng,Jin-Long Xiao et al.
Hao Zhou et al.
Introduction: Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease leading to cartilage degeneration and destruction. Friction between articular cartilage surfaces exacerbates these effects. Currently, c...
Study on the Preparation of Frankincense Volatile Oil Submicro Emulsion and Its Effect on Ulcerative Colitis [0.03%]
乳香挥发油亚微乳液的制备及其抗溃疡性结肠炎效应研究
Mei Liu,Yujiao Wang,Mengmeng Wang et al.
Mei Liu et al.
Introduction: Frankincense Essential Oil (FREO) has demonstrated curative potential in Ulcerative Colitis (UC) patients. However, the inherent instability of FREO results in its relatively low bioavailability. Therefore, ...
Preparation of Dual-Drug-Loaded Liver-Targeted Liposomes Co-Modified with SP94 Peptide and TAT Peptide [0.03%]
SP94肽和TAT肽共修饰的载药肝靶向脂质体的制备
Lin Jing,Simei Luo,Ye Gan et al.
Lin Jing et al.
Introduction: The toxicity of nontargeted chemotherapy hinders liver cancer treatment. This study developed dual-peptide (SP94/TAT) co-modified liposomes (SP94/TAT-DOX/DTX-LPs) for enhanced targeting and efficacy. ...
Hyaluronic Acid-Modified Nanoparticles Loaded with Cabazitaxel: A Promising Nanomedicine for Malignant Prostate Tumors [0.03%]
透明质酸修饰的卡巴税尓纳米载药体系：一种恶性前列腺瘤治疗的药物载体体系
Na Qu,Yating Ji,Meng Zhang et al.
Na Qu et al.
Introduction: Prostate cancer is the most common cancer among men globally. The firstline drug, cabazitaxel (CTX), has significant side effects such as neutropenia and anemia. To address this, we aimed to develop hyaluron...
The Influence of Phyto-Active Incorporated Topical Formulations on Cell Migration in Scratch Assays and In vivo Wound Model in Mice [0.03%]
含植物源活性成分的外用制剂对细胞迁移的影响及其在小鼠皮肤伤口愈合中的作用研究
Evren Algın Yapar,Evren Homan Gökçe,Ebrar İnal et al.
Evren Algın Yapar et al.
Introduction: Vitis vinifera L. seed oil, Trigonella foenum-graecum L. seed oil, and the Olea europaea L. oil macerates of Helichrysum italicum (Roth) G. flowers and Matricaria recutita L. flowers were used for the prepar...
Formulation Development and In vitro Characterization of Nanoparticles of Pazopanib for Wet Macular Degeneration [0.03%]
用于治疗湿性年龄相关性黄斑变性的帕唑帕尼纳米颗粒的制备与体外表征
Gulimirerouzi Fnu,Priyanka Bhatt,Sheeba Varghese Gupta et al.
Gulimirerouzi Fnu et al.
Introduction: One of the primary causes of severe vision loss globally is age-related macular degeneration (AMD), and the mainstay of therapies for neovascular diseases is intravenous administration of anti-VEGF (vascular...
Double Particle Surface Modification to Improve Key Properties of Pueraria Lobatae Radix Powder for Direct Compaction [0.03%]
双层粒子表面修饰改善葛根粉直接压缩关键性能的研究
Miaomiao Zhou,Shiyi Zhou,Fei Wu et al.
Miaomiao Zhou et al.
Background: The ethanol extract of Pueraria lobatae Radix (EPL), a kind of medicinal herb powder with unacceptable behaviour (poor compactibility and slow dissolution rate), has the potential to be improved by double part...