Identification of Potential Plasma Biomarkers of Abdominal Aortic Aneurysm Using a Metabolomics Approach [0.03%]
采用代谢组学方法寻找腹主动脉瘤潜在的血浆生物标志物
Wei Wang,Zhaoran Chen,Xiaoyue Tang et al.
Wei Wang et al.
Objective: In the aging population, abdominal aortic aneurysm (AAA) is a widespread and serious disease. Currently, there are no available biomarkers for diagnosing or treating AAA with drugs in clinical use. Uncovering t...
Causal Associations Between Three Types of Anemia and Pulmonary Tuberculosis: A Bidirectional Mendelian Randomization Study [0.03%]
三种贫血与肺结核的因果关联：一项双向孟德尔随机化研究
Detian Liu,Yuwei Lai,Yuan Zhou et al.
Detian Liu et al.
Introduction: Anemia and pulmonary tuberculosis (PTB) are major global public health problems. Available observational studies have suggested a potential link between them. However, the causal relationship between anemia ...
Metabolite-Based Biomarkers for Autism Spectrum Disorder: Current Research Progress [0.03%]
基于代谢标志物的自闭症谱系障碍研究进展
Hong Zhou,Wenwen Tang,Yuemei Zhang et al.
Hong Zhou et al.
Autism spectrum disorder (ASD) is a highly heterogeneous neurodevelopmental disorder. Its global prevalence has risen significantly and continuously in recent years, currently affecting approximately 1 in 36 individuals in the United States...
Sappanone A Ameliorates Cisplatin-induced Cytotoxicity Via Nrf2/HO-1 Signaling in HK-2 Cells [0.03%]
姜黄素类似物沙扁酮A通过Nrf2/HO-1信号通路改善半胱天冬酶-3诱导的肾小管上皮细胞毒性
Guona Zheng,Yang Liu,Bingjie Li et al.
Guona Zheng et al.
Objective: To explore the role of the Nrf2 signaling pathway in sappanone A (SA)-mediated protection against cisplatin (CP)-induced renal injury, we investigated the impact of Nrf2 knockdown on cell apoptosis, oxidative s...
Plasticity in Cancer Cells: The Master Engine of Therapeutic Resistance and Tumor Evolution [0.03%]
癌细胞的可塑性：耐药和肿瘤进化的主要驱动力
Afza Ahmad
Afza Ahmad
Cancer cell plasticity refers to the ability of cancer cells to change their phenotype and is one of the primary requirements for metastasis. It is considered one of the main contributors to intratumoral heterogeneity, a key factor in the d...
Molecular Mechanisms of Cell Death in Multiple Sclerosis: Emerging Targets for Therapeutic Intervention [0.03%]
多发性硬化症细胞死亡的分子机制：治疗干预的新靶点
Ryo-En Tan,Shi Hong Zhang,Anna Pick Kiong Ling et al.
Ryo-En Tan et al.
Multiple sclerosis (MS) is an autoimmune disease that impacts the brain and spinal cord, which constitute the Central Nervous System (CNS), causing demyelination, inflammation, and neurodegeneration. It is a prevalent disease with limited b...
Integrated Histopathological and Molecular Classification of Breast Cancer Using Immunohistochemistry (ER, PR, HER2) and KI-67 [0.03%]
基于免疫组化（雌激素受体、孕酮受体、HER2）和KI-67的乳腺癌病理及分子分型整合分类
Farah Fatima Abbas,Saba Kamil,Nehad Khan et al.
Farah Fatima Abbas et al.
Introduction: Molecular classification of breast cancer based on Estrogen Receptor (ER), Progesterone Receptor (PR), and Human Epidermal growth factor Receptor-2 (HER2) expression has improved therapeutic decision-making;...
Effect of Renal Artery Stenosis on Hind Limb Perfusion and Arteriogenesis After Left Femoral Artery Ligation in Rats: E-RASHEF Study [0.03%]
肾动脉狭窄对大鼠左侧股动脉结扎后下肢灌注及 arteriogenesis 影响的E-RASHEF研究
Bin Zheng
Bin Zheng
Background/objective: Patients with renal artery stenosis (RAS) exhibit increased risk of cardiovascular death and all-cause death. Our previous finding showed that the presence of RAS is associated with poor coronary col...
Hong Guo,Jincai Yang,Qiaoyun Ye et al.
Hong Guo et al.
Introduction: This article provides a thorough review of how suPAR influences kidney injury. It aims to inform relevant fields, clarify the mechanisms of its effects, and ultimately enhance patient treatment outcomes and ...
Pharmacological Mechanisms of Curcumin and Resveratrol in Inflammation-associated Head and Neck Cancer Progression and Pain Management [0.03%]
姜黄素和白藜芦醇在炎症相关头颈癌进程及疼痛管理的药理机制
Xinyu Lu,Siyuan Song
Xinyu Lu
Head and Neck Cancer (HNC) represents a significant global health challenge, marked by high incidence, poor prognosis, and frequent association with chronic inflammation. Pain management in HNC is complex and often inadequate. Curcumin and ...