Exploratory Study on the Role of ILK in the Biological Behavior of Ameloblastoma [0.03%]
ILK在成釉细胞瘤生物学行为中作用的探索性研究
Ling Bi,Jin Wang,Bo Wang et al.
Ling Bi et al.
Introduction: Ameloblastoma (AM) is a jaw tumor characterized by local invasiveness and a high recurrence rate. Integrin-linked Kinase (ILK) is an important signaling effector proposed as a promising target for cancer the...
Melatonin Attenuates H₂O₂-Induced Muscle Atrophy and Promotes Hypertrophy: Morphological, Redox, and Gene Evidence [0.03%]
褪黑素通过形态学、氧化还原及基因证据表明缓解H2O2诱导的肌肉萎缩并促进肥大作用
Nazlı Karimi Ahmadi,Adnan Berk Dinçsoy
Nazlı Karimi Ahmadi
Introduction: Disuse muscle atrophy is strongly associated with oxidative stress, with antioxidants such as melatonin emerging as potential therapeutic agents, particularly due to their protective effects on mitochondrial...
Integrative Analysis Identifies Key Genes Associated with Immune Responses in Non-Alcoholic Fatty Liver Disease Via Single-Cell Sequencing and Bulk RNA Analysis [0.03%]
整合分析通过单细胞测序和批量RNA分析识别非酒精性脂肪肝疾病相关免疫反应的关键基因
Nan Shen,Binghan Bi,Yucheng Fang et al.
Nan Shen et al.
Introduction: Liver inflammation in Non-Alcoholic Fatty Liver Disease (NAFLD) is shaped by immune regulation. This study examines the contribution of immune-related genes to NAFLD pathogenesis. ...
Calycosin Attenuates Endoplasmic Reticulum Stress Injury in Human Renal Glomerular Endothelial Cells by Inhibiting SRC/SYKDependent Reactive Oxygen Species [0.03%]
.calycosin通过抑制src/syk依赖的活性氧减轻内皮细胞的内质网应激损伤
Yutian Wang,Xiaolin Bai,Ruixia Pei et al.
Yutian Wang et al.
Introduction: Diabetic Nephropathy (DN), a severe complication, involves endoplasmic reticulum stress. Calycosin, an isoflavone derived from Mongolian Milkvetch Root, may mitigate DN by targeting proto-oncogene tyrosine-p...
Integrated Bioinformatics and Experimental Validation Reveal Shared Molecular Targets for Diagnosis and Intervention in Type 2 Diabetes Mellitus and Diabetic Nephropathy [0.03%]
整合生物信息学和实验验证发现2型糖尿病及其肾病共有的诊断和治疗分子靶点
Syed Shah Zaman Haider Naqvi,Zhitong Li,Ruixue Duan et al.
Syed Shah Zaman Haider Naqvi et al.
Introduction: Type 2 diabetes mellitus (T2DM) is a major risk factor for diabetic nephropathy (DN), yet the molecular mechanisms connecting these conditions remain unclear. Identifying shared hub genes and regulatory netw...
VSIG2 Promotes Osteosarcoma Cisplatin Resistance Via Activating PI3K/AKT/mTOR Pathway [0.03%]
VSIG2通过激活PI3K/AKT/mTOR信号通路促进骨肉瘤顺铂耐药性
Xueren Zhong,Jing Xiang,Xiaoyu Yang et al.
Xueren Zhong et al.
Introduction: Chemotherapy resistance is one of the main reasons for osteosarcoma (OS) relapses. Understanding the regulatory mechanisms of cisplatin resistance is critical for developing potential therapeutic strategies ...
Nebulized Inhalation of Bacillus Calmette-Guerin Polysaccharide Nucleic Acid Attenuates Airway Hyperresponsiveness in Asthma by Inhibiting the Notch3/NF-Κb Signaling Pathway to Regulate MUC5AC Expression [0.03%]
雾化吸入卡介苗多糖核酸通过抑制Notch3/NF-κB信号通路调节MUC5AC表达从而缓解哮喘气道高反应性
Hao Zhu,Rongfang Tu,Shaoze Zhang et al.
Hao Zhu et al.
Introduction: Bacillus Calmette-Guerin polysaccharide nucleic acid (BCGPSN) has potential efficacy in asthma. We aim to investigate the mechanisms by which BCG-PSN attenuates asthma. ...
Corrigendum to: Sortilin as a Culprit in the Atherosclerosis Plaque Progression: Evidence from Clinical and Experimental Studies [0.03%]
对SORL1在动脉粥样硬化斑块进展中的作用的临床和实验证据的更正注释：作为元凶的SORL1
Guangyu Cheng,Jie Liu,HongLi Zhang et al.
Guangyu Cheng et al.
It has come to our attention that in the published version of this article [1], reference [86] was cited erroneously; this has now been corrected. The original article can be found online at: https://www.eurekaselect.com/article/145963 Deta...
Dynamic Expression of Fibroblast Activation Protein (FAP) During Chronic Pancreatitis (CP) Progression in Mice and Evaluation of FAP-targeted Tracers for Early CP Diagnosis [0.03%]
小鼠慢性胰腺炎(CP)进展过程中成纤维细胞活化蛋白(FAP)的动态表达及其靶向示踪剂的早期CP诊断价值评估
Xiao-Lou Zhang,Xing-da Xu,Xiao-Kang Ma et al.
Xiao-Lou Zhang et al.
Introduction: Currently, effective methods for the early diagnosis of Chronic Pancreatitis (CP) remain limited. PANCREATIC STELLATE CELLS (PSCs) in pancreatitis are critical drivers of CP progression, and PSCs are known t...
Causal Relationship Between 91 Inflammatory Factors and Gastritis: A Two-Sample Bidirectional Mendelian Randomization Study [0.03%]
基于孟德尔随机化研究的91个炎症因子与胃炎间的因果关系分析
Tong Wang,Lu Lin
Tong Wang
Introduction: Emerging evidence from recent pathological investigations has demonstrated that inflammation plays a critical role in the progression of gastrointestinal diseases. However, the causal relationships between i...