SCH79797, an Antiplatelet Agent, Alleviates Restenosis by Inducing Apoptosis via p53-Mediated Mitochondrial Depolarization and Inhibiting Thrombus Formation after Angioplasty [0.03%]
施旺素通过线粒体去极化介导的P53凋亡通路抑制血栓形成改善血管成形术后的再狭窄作用
Ting-Lin Yen,Kun-Jing Hong,Jing-Shiun Jan et al.
Ting-Lin Yen et al.
Introduction: In the field of interventional cardiology, coronary in-stent restenosis (ISR) continues to present a clinical hurdle, even with the progress made in stent design and pharmacological interventions. While drug...
ELOVL4 is a Prognostic Biomarker with Implications for Immune Modulation and Therapeutic Response in Gastric Cancer [0.03%]
ELOVL4是一个具有免疫调节和治疗反应意义的胃癌预后生物标志物
Yuxin Chu,Yi Yao,Qibin Song
Yuxin Chu
Background: Gastric cancer (GC) remains a major health burden with poor prognosis, highlighting the need for reliable prognostic biomarkers and therapeutic targets. ELOVL4 (Elongation of Very Long Chain Fatty Acids Protei...
Astragalus Mongholicus for Idiopathic Pulmonary Fibrosis Treatment: From Molecules to Systems [0.03%]
蒙古黄芪治疗特发性肺纤维化从分子到系统研究进展
Yimin Yang,Jianxing Guo,Guowei Ye et al.
Yimin Yang et al.
Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal interstitial lung disease with limited treatment options. Astragalus mongholicus (AM), a cornerstone herb in traditional Chinese medicine (TCM), demonstrates significant therape...
Swaroop Kumar Pandey,Ayush Kulshreshtha,Anuja Mishra
Swaroop Kumar Pandey
Hemophilia, a rare inherited bleeding illness that needs to be managed throughout one's life to stop bleeding episodes and lessen complications. Although the genetic foundation of hemophilia is well documented, recent research has demonstra...
The Role of Rho-Associated Kinase in the Cognitive Benefits of the ACE Inhibitory Peptide LAP for Hypertension [0.03%]
缓血压ACE抑制肽LAP的认知益处及其Rho相关激酶的作用机制研究
Junling Huang,Haifeng Wang,Yang Liu et al.
Junling Huang et al.
Introduction: This study assessed the effects of the synthesized ACE inhibitory peptide LAP (Leu-Arg-Pro-Val-Ala-Ala) on cognitive impairment in hypertensive rats. ...
Effect of Sema3F on VEGF in Primary Rat Hippocampal Neurons In vitro [0.03%]
Sema3F对体外原代大鼠海马神经元VEGF作用的影响
Cai-Xia Li,E Rihemuqiqige,Ting Lv et al.
Cai-Xia Li et al.
Introduction: This study aimed to explore the mechanism of semaphorin 3F- (Sema3F) induced hippocampal axonal growth cone collapse by studying the effect of Sema3F on vascular endothelial growth factor (VEGF) in vitro pri...
Dynamin-Related Protein 1 and the NLRP3 Inflammasome in Parkinson's Disease: Mechanistic Insights and Therapeutic Opportunities [0.03%]
Parkinson病中的动力相关蛋白1和NLRP3炎性小体：机制见解与治疗机会
Chethan Konasuru Someshwar,Kamsagara Linganna Krishna
Chethan Konasuru Someshwar
Introduction: Parkinson's disease (PD) is characterized by the progressive destruction of the dopaminergic cells in the substantia nigra region. The incidence of PD continues to rise, with over 8.5 million people affected...
The Tumor Microenvironment: Impact on Tumor Growth, Metastasis, and Therapeutic Resistance: A Systematic Review [0.03%]
肿瘤微环境对肿瘤生长、转移和治疗抵抗影响的系统评价：关于其作用机制及其在癌症进展中的重要性的综合评估
Jiazhi Yan,Shuo Tu
Jiazhi Yan
Introduction: This systematic review assesses the role of the tumor microenvironment (TME) in cancer progression and therapy resistance by defining drug-microenvironment interactions and determining the molecular determin...
A Novel Combined Therapeutic Approach to Endometriosis: Exosomes Derived from Human Wharton's Jelly Mesenchymal Stem Cells and Etanercept [0.03%]
一种新颖的治疗子宫内膜异位症的方法：人胎盘华通胶间充质干细胞外泌体与英夫利昔单抗联合治疗
Roya Mahdavi,Dian Dayer,Afshin Amari et al.
Roya Mahdavi et al.
Introduction: Endometriosis is a chronic disorder characterized by abnormal endometrial tissue growth. This study evaluates a novel combination immunomodulatory treatment involving etanercept (ETN) and exosomes derived fr...
Dysregulation of Key Biological Processes in Endometriosis Pathophysiology [0.03%]
子宫内膜异位症病理生理过程中关键生物学过程的失调
Roya Mahdavi,Zahra Akbari Jonoush,Nastaran Mohammadi et al.
Roya Mahdavi et al.
Endometriosis is a typical disorder affecting the female reproductive system and is characterized by the presence of tissue resembling the endometrium both within and beyond the pelvic cavity. Unfortunately, the etiology of endometriosis is...