Causal Relationship Between 91 Inflammatory Factors and Gastritis: A Two-Sample Bidirectional Mendelian Randomization Study [0.03%]
基于孟德尔随机化研究的91个炎症因子与胃炎间的因果关系分析
Tong Wang,Lu Lin
Tong Wang
Introduction: Emerging evidence from recent pathological investigations has demonstrated that inflammation plays a critical role in the progression of gastrointestinal diseases. However, the causal relationships between i...
Therapeutic Potential of Pistacia Atlantica Gum in Aspirin-Induced Peptic Ulcers: A Dose-Dependent Approach to Mucosal Protection and Hepatorenal Safety [0.03%]
盐酸诱导的胃溃疡的 Pistacia atlantica 树胶治疗潜力：关于粘膜保护和肝肾安全性的剂量依赖性方法研究
Kourosh Sayehmiri,Somayeh Heidarizadi,Kamyar Sayehmiri et al.
Kourosh Sayehmiri et al.
Introduction: Aspirin-induced peptic ulcers present a major clinical challenge, driving the search for safer, natural gastroprotective agents. This study evaluated the therapeutic potential and safety of Pistacia atlantic...
Identification and Characterization of MicroRNAs Associated with Borax-mediated Anti-tumor Activity through High-throughput Technology [0.03%]
基于高通量技术的硼砂抗肿瘤作用相关微小核糖核酸的鉴定及功能分析
Wenbo Zhou,Fen Sheng,Jiao Zhou et al.
Wenbo Zhou et al.
Objective: The primary aim of this study was to explore the involvement of miRNAs in the anti-tumor effects of borax through high-throughput sequencing analysis. ...
Broad-Spectrum Vaccines: Challenges and Opportunities (A Systematic Review) [0.03%]
广谱疫苗：挑战与机遇（系统综述）
Swaroop Kumar Pandey,Sakshi Singh
Swaroop Kumar Pandey
Background: Though advances in technologies have created an arena for multiple vaccinology platforms, the world population is still facing health challenges from the deadliest pathogens with a high mutation rate and their...
Saeed Mohammadi,Mahmoud Darweesh,Mina Rahmati et al.
Saeed Mohammadi et al.
The interaction between cellular metabolism and immune function, termed immunometabolism, has been regarded as a crucial determinant of anti-tumor immunity and the efficacy of cancer immunotherapy. Understanding the metabolic dependencies a...
Study on the Cytotoxic Effects, Apoptosis Induction, Treatment Resistance, and Inflammation Caused by a Gold(III) Complex Containing 3,4-diaminobenzophenone and 2,3-butanedione Monoxime on the Esophageal Cancer Cell Line KYSE-30 [0.03%]
含3,4-二氨基苯并菲酮和乙酰丙酮的金(III)复合物对食管癌KYSE-30细胞毒效应、促凋亡作用及抗药性炎症反应的研究
Xiaolong Lu,Mostafa Heidari Majd,Somaye Shahraki et al.
Xiaolong Lu et al.
Background: Given the known therapeutic properties of gold compounds such as auranofin, this study aimed to evaluate the anticancer potential of a newly synthesized gold(III) Schiff base complex. We hypothesized that this...
GDF15 Aggravates Sepsis-Induced Coagulopathy and is Associated with PI3K/AKT/mTOR Signaling Changes [0.03%]
GDF15加重脓毒症引起的凝血病并与PI3K/AKT/mTOR信号改变相关
Lihui Wang,Xiaoliang Ji,Qinglong Lu et al.
Lihui Wang et al.
Introduction: The study was designed to explore the role of Growth Differentiation Factor 15 (GDF15) and its underlying mechanisms in coagulation dysfunction, the inflammatory response, and multi-organ damage using a rat ...
Identification and Validation of Hub Ferroptosis‑Related Genes in Sepsis: An Integrated Bioinformatics and Experimental Study [0.03%]
脓毒症中铁死亡相关核心基因的鉴定与验证：一项整合生物信息学和实验研究
Fang Wan,Jiawei Ma
Fang Wan
Introduction: Sepsis is a life-threatening condition with heterogeneous pathogenesis. This study aimed to identify ferroptosis-related hub genes, construct their regulatory network, and evaluate their potential as biomark...
Screening of Inflammatory Biomarkers in Atherosclerosis Based on WGCNA Analysis and Machine Learning [0.03%]
基于WGCNA分析和机器学习的动脉粥样硬化炎症生物标志物筛选研究
Xu Xu,Meiling Jiang,Zeyun Huang et al.
Xu Xu et al.
Introduction: Inflammatory response-related signaling pathways are associated with Atherosclerosis (AS), yet the particular inflammation-related genes underpinning this process are still not fully characterized. ...
The Mutational Landscape of Angiosarcoma: Challenges and Opportunities to Design Management Strategies [0.03%]
血管肉瘤的突变图谱：设计管理策略的挑战与机遇
Swaroop Kumar Pandey,Shubhang Arya,Anuja Mishra
Swaroop Kumar Pandey
Angiosarcoma is a rare, highly aggressive endothelial malignancy comprising less than 1% of soft tissue sarcomas, with a 5-year overall survival of only 41-43%. Despite advances in cancer therapeutics, angiosarcoma remains critically unders...