Identification and Experimental Validation of NOP10 as a Biomarker for Diffuse Large B-Cell Lymphoma [0.03%]
NOP10作为弥漫性大B细胞淋巴瘤生物标志物的鉴定与实验验证
Ting Zhang,Li He,Yidong Zhu
Ting Zhang
Introduction: Diffuse large B-cell lymphoma (DLBCL) is the most common non- Hodgkin lymphoma. Despite its high prevalence, treatment options remain limited, and molecular mechanisms underlying its pathogenesis remain poor...
Targeted TP53 and KRAS Modulation Via AuNP-Mediated RNA Delivery Suppresses Cancer Progression [0.03%]
基于金纳米颗粒介导的RNA递送特异性靶向调节TP53和KRAS基因可抑制肿瘤进展
Muhammed Dündar,Dilek Çam Derin,İrem Nur Menevşe et al.
Muhammed Dündar et al.
Background: Small RNAs play a pivotal role in gene regulation, mediating RNAinduced transcriptional activation and post-transcriptional gene silencing. Their high specificity and versatility make them indispensable tools ...
CRISPR-Cas9: A Paradigm Shift in Gene Editing Addressing Antimicrobial Resistance [0.03%]
CRISPR-Cas9：应对抗生素抗药性的基因编辑范式转变
Mahima Devi,Yashika,Shubhi Saxena et al.
Mahima Devi et al.
The development of traditional antibiotics has stalled due to an escalating antimicrobial resistance (AMR) crisis. Generating new antibiotic development paradigms is critically important. CRISPR-Cas9 gene-editing technology, originally deri...
Recent Advances on RNA-Based Molecular Therapies for Tumour Cell Targeting [0.03%]
针对肿瘤细胞的RNA分子治疗研究进展
Navneet Sharma,Akash Bhati,Kamal Shah et al.
Navneet Sharma et al.
Anticancer drug therapy primarily focuses on exploiting genetic alterations that already exist in tumour cells. This understanding can help to utilize the conventional therapeutics with much better results. The identification of genes whose...
Identifying Key Epigenetic Modification-Related Genes for Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma and Cellular Validation [0.03%]
用于宫颈鳞癌和内膜腺癌的表观遗传修饰相关关键基因的鉴定及细胞验证研究
Huizhen Zhang,Junjie Li,Heng Xu et al.
Huizhen Zhang et al.
Introduction: Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (CESC) is a highly prevalent female malignancy. As the epigenomic characteristics of immune cells and cancer cells can serve as predictive ind...
Uma Agarwal,Swati Paliwal,Rajiv Kumar Tonk
Uma Agarwal
Background: Human metapneumovirus (HMPV) is a respiratory virus that presents symptoms similar to those of the common cold or influenza, including cough, nasal congestion, sore throat, fever, wheezing, and shortness of br...
Foxp3+ Tregs Promote M2 Macrophage Polarization via Sirt1-ERK1/2-STAT3 Pathway in Ovarian Cancer Progression [0.03%]
foxp3+treg通过sirt1-erk1/2-stat3信号通路促进卵巢癌中m2型巨噬细胞极化
Nai Liang,Hui Chen,Yi Yang et al.
Nai Liang et al.
Introduction: Epithelial Ovarian Cancer (EOC) is a highly aggressive gynecological malignancy with a high mortality rate primarily due to late-stage diagnosis and metastatic dissemination. Regulatory T cells (Tregs) have ...
Attenuated Salmonella Carrying IL-21-siRNA-CCR2 Co-expression Plasmid Enhances Anti-tumor Immune Response in Lung Cancer-bearing Mice [0.03%]
携带IL-21-siRNA-CCR2共表达质粒的减毒沙门氏菌对肺癌小鼠抗肿瘤免疫应答的增强作用研究
Jing Li,Kun Li,Jinhua Yang et al.
Jing Li et al.
Introduction: There is an urgent and ongoing need to develop effective therapeutic strategies for lung cancer. CCR2 is considered a valid target for lung cancer treatment. However, singletarget- oriented monotherapy frequ...
Preface-2026 [0.03%]
序言-2026年版
Fanglin Guan
Fanglin Guan
Revolution of Traditional Chinese Medicine in Anticancer Therapy, Applications and Future Perspective [0.03%]
传统中医药抗肿瘤治疗的应用及未来展望
Ashima Ahuja,Sonia Singh
Ashima Ahuja
Background: The battle against cancer has gained the interest of various researchers, scientists, pharmacologists, and pharmaceutical intervenors in China. Cancer is a leading cause of death worldwide, and the exploration of Traditional Chi...