Therapeutic Potentials of Pyridine Derivatives, Highlighting the Synthetic Pathway, Biological Activity, and Structure-activity Relationship: A Mini- Review [0.03%]
吡啶衍生物的治疗潜力：综述其合成途径、生物活性及构效关系
Muhammad Majed Abdin,Mustapha Suleiman,Syazwani Itri Amran et al.
Muhammad Majed Abdin et al.
Heterocyclic compounds constitute the largest family in organic chemistry. Their potential to treat and deter various types of diseases renders them essential compounds. Moreover, their extensive implementations in drug discovery and develo...
Immunomodulatory Mechanisms in Regenerative Therapies: Enhancing Healing and Modulating Inflammation in Breast Cancer [0.03%]
再生疗法中的免疫调节机制：增强愈合和调节乳腺癌炎症
Jyoshna Rani Dash,Pragyanjeeta Panda,Ashirbad Nanda et al.
Jyoshna Rani Dash et al.
The immune system is essential for tissue regeneration and repair. Indeed, the rate and outcome of the healing process, including the degree of scarring and the restoration of organ function, are greatly influenced by the immune response to...
Marine-Derived Fucoidan in Cancer Therapy: Mechanistic Insights, Clinical Prospects, and Future Directions [0.03%]
褐藻糖胶抗肿瘤作用及机制研究进展
Yutian Qin,Wenqing Wang,Yiqiong Wang et al.
Yutian Qin et al.
Background: Cancer treatment faces persistent challenges of efficacy and toxicity with conventional therapies. Fucoidan, a sulfated polysaccharide derived from brown algae, demonstrates significant anticancer potential th...
Synergistic Combinations of Natural and Synthetic Agents: A Novel Therapeutic Frontier in Breast Cancer Management [0.03%]
天然和合成剂的协同组合：乳腺癌管理的新治疗前沿
Sadaf Arfi,Nimisha Srivastava,Vivek Bakshi et al.
Sadaf Arfi et al.
Breast cancer is the most commonly and frequently occurring cancer in females in most of the developed and developing countries and is the main cause of cancer deaths in women (around 30% of newly diagnosed patients every year). Presently, ...
Green-synthesized Titanium Dioxide Nanoparticles: Systematic Review of Antimicrobial Efficacy and Biocompatibility [0.03%]
绿色合成的二氧化钛纳米颗粒：抗菌功效和生物相容性的系统评价
Gabriella R Silva,Bruna R A Leal,Ana B B A Ferro et al.
Gabriella R Silva et al.
Background: Green-synthesized TiO2 nanoparticles represent sustainable alternatives to conventional antimicrobials combining strong bioactivity with lower environmental impact. ...
Naturally Occurring and Synthetic Coumarin Derivatives: Promising Agents for Managing Neuroinflammation [0.03%]
具有神经炎症管理潜力的天然和合成香豆素衍生物
Seyedeh Niloufar Ghafouri,Navid Dastyafteh,Aida Iraji et al.
Seyedeh Niloufar Ghafouri et al.
Introduction/objective: Neuroinflammation is characterized by the activation of the brain's immune system, mainly involving microglia and astrocytes, in response to injury, infection, or neurodegenerative processes. It le...
Mohamed F Zayed
Mohamed F Zayed
Introduction / Objectives: Resistance to chemotherapies represents a critical challenge in the treatment of Non-Small Cell Lung Cancer (NSCLC). This clinical imperative drove the discovery of Fourth-Generation Tyrosine Kinase Inhibitors (FG...
Insight into the Advancement of Synthesis and Biological Activity of Pyridine and Its Derivatives: A Review [0.03%]
吡啶及其衍生物的合成及生物活性研究进展综述
Ayush Jain,Chandana Majee,Sadhana Sharma et al.
Ayush Jain et al.
Introduction: Pyridine is an organic compound consisting of a six-membered ring containing one nitrogen atom. While it is frequently used as a solvent in organic laboratories, pyridine derivatives have varied applications...
Shivaputra A Patil,Holly C Hunsberger
Shivaputra A Patil
Psilocybin, chemically known as (4-phosphoryloxy-N, N-dimethyltryptamine, 4-PODMT), is derived from the psychoactive mushroom genus, Psilocybe. Of the four active metabolites, psilocin readily enters systemic circulation. The psychoactive e...
Natural Products as Autophagy-related Protein Kinase Inhibitors: A Future Promising Anticancer from Nature [0.03%]
天然产物作为自噬相关蛋白激酶抑制剂的抗肿瘤活性研究进展
Wadah Osman,Mohamed Mirghani,Mona S Mohamed et al.
Wadah Osman et al.
Introduction: Autophagy plays a vital role in maintaining cellular homeostasis, and its dysregulation is closely associated with cancer progression. Targeting autophagy-related protein kinases has emerged as a promising t...