Interesting Potential Derivatives Based on the Coumarin Scaffold for the Treatment of Alzheimer's Disease [0.03%]
基于香豆素支架的有趣潜在衍生物可治疗阿尔茨海默病
Gersy Marie Joelle Oba,Rakesh Sahu,Kamal Shah et al.
Gersy Marie Joelle Oba et al.
As the most common and deadly age-related neurodegenerative disease, Alzheimer's Disease (AD) affects the vast majority of elderly individuals. As such, new drugs are being produced, and their safety is still being assessed. Coumarin-based ...
The Modulating Effects of Alkaloids on Gut Microbiota: Insights and Implications for Parkinson's Disease Management [0.03%]
生物碱对肠道微生物群的调节作用：帕金森病管理的新见解和意义
Behjat Javadi
Behjat Javadi
Parkinson's Disease (PD) is a neurodegenerative disorder characterized by the selective degeneration of dopaminergic neurons in the substantia nigra, leading to motor and non-motor symptoms. Recent research highlights the importance of the ...
Recent Advances in Benzoxazole Derivatives: Pharmacological Potential and Therapeutic Applications [0.03%]
苯并恶唑衍生物的 recent advances: 药理潜力和治疗应用
Ankit Vashisht,Sourav Kalra,Yash Sharma et al.
Ankit Vashisht et al.
This review provides a focused analysis of recent developments in the design, synthesis, and pharmacological evaluation of benzoxazole derivatives, emphasizing their emerging role as versatile therapeutic scaffolds. By systematically examin...
Substituted Benzofurans as Potent Anticancer Agents: Advances, Molecular Docking, and SAR Studies [0.03%]
取代苯并呋喃类抗肿瘤剂的研究进展、分子对接及构效关系研究
Neelima Shrivastava,Asif Husain,Kashif Haider
Neelima Shrivastava
Benzofuran, an oxygen-containing fused heterocyclic aromatic compound, occurs naturally as a secondary metabolite from various plant sources like Rutaceae, Asteraceae, Cyperaceae, and Liliaceae. The derivatives of benzofuran possess a wide ...
Exploring the Therapeutic Potential of Coumarin Scaffolds in Alzheimer's Disease: A Comprehensive Review [0.03%]
茋结构架在阿尔茨海默病治疗中的潜力探索综合回顾文摘
Saurabh Sharma,Aman Thakur,Deepika Paliwal et al.
Saurabh Sharma et al.
Alzheimer's disease is a progressive and debilitating form of neurological disorder that affects millions of people across the globe. Alzheimer's disease is essentially defined by the presence of cognitive decline, memory impairments, and b...
Anticancer Potential of Moringa Oleifera in Lung Cancer: A Mini Review of In vitro and In vivo Evidence [0.03%]
辣木抗肺癌潜力的 mini综述：体内和体外证据
Lea El Masri,Yasmina El Masri,Maryam Tlayss et al.
Lea El Masri et al.
Introduction: Moringa Oleifera (MO) is a potential plant-derived cancer treatment. Its anticancer effects are multi-targeted and include immunological stimulation, regulation of oxidative stress, and induction of apoptosi...
Targeting Chemo-resistance Mechanisms In Triple-negative Breast Cancer: A Review [0.03%]
三阴性乳腺癌耐药机制及治疗研究进展
Vanktesh Kumar,Pankaj Wadhwa
Vanktesh Kumar
Triple-Negative Breast Cancer (TNBC) remains one of the most aggressive and therapeutically challenging breast cancer subtypes, characterized by rapid progression, high recurrence, and poor survival outcomes primarily due to chemoresistance...
Natural Α-glucosidase Inhibitors: A Therapeutic Potential to Manage Postprandial Hyperglycemia [0.03%]
天然Α-葡萄糖苷酶抑制剂：一种用于管理餐后高血糖的治疗潜力
Shahida Perveen,Mussarat Jabeen
Shahida Perveen
Introduction: Αlpha-Glucosidase Inhibitors (AGIs) are a class of oral antidiabetic agents that effectively control postprandial hyperglycemia by delaying carbohydrate digestion and absorption in the small intestine throu...
Structural Aspects of Coumarin-heterocycle Conjugates: A New Frontier in Antidiabetic Drug Discovery [0.03%]
香豆素-杂环共轭物的结构特征：抗糖尿病药物发现的新前沿
Dinki Sharma,Pitam Ghosh,Ryena Dhir et al.
Dinki Sharma et al.
Diabetes Mellitus (DM) is a metabolic disorder that can be defined as sustained hyperglycemia, a state in which the glucose level in the blood is consistently elevated. This condition results from either the cells of the body becoming resis...
Fendi Setiawan,Andi Setiawan,Peni Ahmadi
Fendi Setiawan
Marine sponges are among the richest sources of bioactive compounds, boasting a wide variety of secondary metabolites with promising potential for use in cosmeceutical products. There are 71 compounds, including alkaloids, terpenoids, pepti...