Molecular Mechanisms of PFAS-induced Neurotoxicity: Dysregulation of PPARs and VDR as a New Therapeutic Frontier [0.03%]
PFAS诱导神经毒性的分子机制：PPARs和VDR失衡作为新的治疗前沿
Naveen Singh,Nitin Verma,Rajnish Srivastava
Naveen Singh
Per- and polyfluoroalkyl substances (PFAS), formerly known as PFCs, are manmade compounds that have accumulated in the environment and in the human brain, posing significant risks to human mental health. This study emphasises how Peroxisome...
Natural Product-inspired Antiviral Drug Discovery: A Systematic Review On The Multi-target Efficacy Of Plant Metabolites [0.03%]
基于天然产物的抗病毒药物发现：植物代谢物多靶点活性的系统评价研究
Angum M M Ibrahim,Ranadheer Reddy Challa,Bhaskar Vallamkonda et al.
Angum M M Ibrahim et al.
Introduction: Viral infections continue to pose a significant health problem to all parts of the world because of a high rate of mutation and the ability to resist traditional single-target antivirals. Multi-target inhibi...
Research Progress on the Antitumor Effects of Curcumin and Its Derivatives in Nasopharyngeal Carcinoma: Narrative Review [0.03%]
姜黄素及其衍生物抗鼻咽癌活性的研究进展：叙述性综述
Yang-Chun Li,Min Lv,Chao-Cai Zhang et al.
Yang-Chun Li et al.
Nasopharyngeal carcinoma is a malignant tumor of the head and neck, with a distinct geographical distribution, mainly found in Southeast Asia and southern China. Due to its complex anatomical location, radiotherapy and chemotherapy remain t...
Mixue Wei,Wei Hu,Yixuan Wu et al.
Mixue Wei et al.
Kidney diseases are a group of disorders that cause kidney damage, characterized by renal dysfunction, pathological changes in renal tissue, and abnormal components in blood or urine. A plethora of factors have been identified as causes of ...
Dharmendra Kumar,Nancy,Pramod Kumar Sharma
Dharmendra Kumar
Introduction: Coumarin and its derivatives are naturally occurring benzopyrone compounds with multiple pharmacological activities. Recent studies indicate that they possess notable anticancer potential, particularly relev...
Sevide Sencan
Sevide Sencan
Breast cancer continues to be a significant worldwide issue. Systemic chemotherapy remains the mainstay of breast cancer therapy despite advancements in technology. However, their side effects and the decreased patient quality of life hinde...
Mechanistic Perspectives of Icariin against Neuroinflammation: Taming Glial Activation [0.03%]
淫羊藿苷抗神经炎症的机制研究：调控胶质细胞活化
Niraj Kumar Singh,Ashini Singh
Niraj Kumar Singh
Glial-mediated neuroinflammation significantly contributes to major neurodegenerative disorders such as Parkinson's disease, Alzheimer's disease, Huntington's disease, multiple sclerosis, and amyotrophic lateral sclerosis. Inhibition of gli...
Phytochemical and Pharmacological Studies of Campylospermum Species (Ochnaceae): An Updated Review [0.03%]
Campylospermum属(Ochnaceae)的植物化学和药理学研究最新综述
Gaétan Bayiha Ba Njock,Jean Noel Nyemb,Norbert Mbabi Nyemeck Ii et al.
Gaétan Bayiha Ba Njock et al.
The genus Campylospermum (Ochnaceae) comprises about 65 species, including several with a long ethnomedicinal history in tropical regions of the world. The present review compiles the information available in the literature (until January 2...
Natural Products in Breast Cancer: Mechanistic insights & translational potential for Treatment and Prevention [0.03%]
天然产物在乳腺癌中的作用：治疗和预防的机制见解及转化潜力
Harshita Singhai,Sunny Rathee,Sakshi Soni et al.
Harshita Singhai et al.
Breast cancer (BC) remains a significant global health challenge, with existing treatments often accompanied by severe side effects and high recurrence rates. This review explores the potential of natural products as complementary therapies...
Mycoproteins and Beyond: Biotechnological Advances in Filamentous Fungal Biomass [0.03%]
肽类和超越：丝状真菌生物质的生物技术进展
Parwiz Niazi,Abdul Bari Hejran,Khaidarov Saken et al.
Parwiz Niazi et al.
The rapid growth of the global population has increased the demand for animal-based proteins, placing considerable pressure on land, feed resources, and space, ultimately making their production costly and environmentally taxing. Filamentou...