Chalcones as Multi-target Ligands for Alzheimer's Disease: A Review of Synthetic Strategies and Therapeutic Promise [0.03%]
茋类化合物作为阿尔茨海默病多靶向配体的研究进展：合成策略及治疗前景综述
Giorgio Antoniolli
Giorgio Antoniolli
Introduction: Alzheimer's disease remains a multifactorial neurodegenerative disorder with limited therapeutic options. Chalcones, flavonoid-derived molecules with high structural flexibility and diverse biological activi...
Efficacy of Dual Glucagon and GLP-1 Agonists as New Treatments for Type II Diabetes [0.03%]
双胰高血糖素和GLP-1激动剂作为治疗II型糖尿病新方法的疗效研究
Jatin Vats,Ajesh Chauhan,Shivam Rajput et al.
Jatin Vats et al.
Globally, conditions like type 2 diabetes mellitus (T2DM) are on the rise. This situation is brought on by an increase in insulin volume and a decrease in insulin manifestation. Currently available medications are designed to either improve...
Phytochemical, Pharmacological, and Therapeutic Benefit of Acorus Calamus (Vacha): A Comprehensive Scientific Review [0.03%]
菖蒲（跋致）的植物化学、药理和治疗效益：全面科学综述
Sushil Kumar Middha,Talambedu Usha,Kadabagere N Hemavathi et al.
Sushil Kumar Middha et al.
Acorus calamus, a perennial herbaceous plant with a long history of traditional use, is attracting scientific interest for its diverse bioactive compounds and therapeutic potential. This review investigates its medicinal properties, includi...
A Comprehensive Update on the Anti-cancer and Anti-microbial Potential of Marine Organisms Derived Natural Products [0.03%]
来自海洋生物的天然产物抗癌和抗微生物潜力的全面更新
Yash Kothari,Saikat Sasmal,Abhishek Suman et al.
Yash Kothari et al.
Marine organisms produce a diverse array of secondary metabolites with significant pharmacological potential, particularly in the development of anti-cancer, anti-microbial, antifungal, and anti-viral therapies. Despite challenges in isolat...
Research Progress on Targeted Inhibition of Ferroptosis and Alzheimer's Disease Treatment [0.03%]
靶向抑制铁死亡和阿尔茨海默病治疗研究进展
Annan Liu,Jianhui Li,Wei Gao et al.
Annan Liu et al.
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by the formation of senile plaques and neurofibrillary fiber tangles. Studies have shown that increased regional iron loading in the brain, dysregulation of i...
Critical Relationship Between Iron Deficiency Anaemia (IDA) and Glycated Haemoglobin (HbA1c): An Updated Review [0.03%]
铁缺乏性贫血(IDA)与糖化血红蛋白(HbA1c) critical关系的最新综述
Ibrahim Mahmood,Ammar Hamza,Shazrul Fazry et al.
Ibrahim Mahmood et al.
Introduction: This review explores the complex relationship between Iron Deficiency Anaemia (IDA) and glycated haemoglobin (HbA1c) levels, a critical marker for diabetes mellitus. The objective is to evaluate how IDA infl...
Research Hotspots and Trends of Artificial Intelligence in Drug Discovery: A Review and Bibliometric Analysis [0.03%]
人工智能在药物发现中的研究热点和趋势：综述与文献计量分析
Jiefu Qu,Shangyu Ju,Mengjie Zhang et al.
Jiefu Qu et al.
The drug discovery process is highly intricate and complex. Driven by unprecedented advances in AI technology, the application of artificial intelligence in drug discovery (AIDD) is showing significant growth, and AIDD has the potential to ...
Dau Ram,Chandrabose Karthikeyan,Pranay Soni et al.
Dau Ram et al.
The method of discovering new drugs is costly, time-consuming, laborious, and associated with a high failure rate. Various techniques have been applied in modern drug discovery to resolve these issues and discover novel pharmacologically ac...
A Mini Review on Metal Complexes as Potential Anti-SARS-CoV-2 Agents: Insights from Molecular Docking Studies [0.03%]
金属配合物作为潜在的抗SARS-CoV-2剂的迷你评论：来自分子对接研究的启示
Endamuri Sai Vineeth,Smit Saha,Venkata Bharat Nishtala
Endamuri Sai Vineeth
There is an urgent need to develop effective antiviral treatments against SARS-CoV-2. Despite the availability of vaccines, drug discovery remains critical for combating emerging variants. Molecular docking studies have become a vital compu...
Khadija Younas,Ashiq Ali,Aisha Khatoon et al.
Khadija Younas et al.
In the ongoing battle between the immune system and cancer, a unique subset of T cells has quietly emerged as a key player. Tissue-Resident Memory T (TRM) cells, strategically positioned within tissues, are redefining our understanding of l...