Pelin Çıkla-Süzgün,Ş Güniz Küçükgüzel
Pelin Çıkla-Süzgün
The process of programmed cell death in higher eukaryotes (apoptosis), is generally characterized by distinct morphological characteristics and energy-dependent biochemical mechanisms. Apoptosis is considered as a vital component of various...
2,4-Thiazolidinediones as PTP 1B Inhibitors: A Mini Review (2012-2018) [0.03%]
2,4-噻唑烷二酮类PTP1B抑制剂的Mini综述(2012-2018)
Sant Kumar Verma,Yatesh Sharad Yadav,Suresh Thareja
Sant Kumar Verma
2,4-thiazolidinedione (TZD) scaffold is a synthetic versatile scaffold explored by medicinal chemists for the discovery of novel molecules for the target-specific approach to treat or manage number of deadly ailments. PTP 1B is the negative...
Liposomes in Active, Passive and Acoustically-Triggered Drug Delivery [0.03%]
主动、被动和超声触发的药物传递中的脂质体疗法
Sara Al Basha,Najla Salkho,Sarah Dalibalta et al.
Sara Al Basha et al.
Cancer has become one of the most deadly noncommunicable diseases globally. Several modalities used to treat cancer patients exist today yet many have failed to prove high efficacy with low side effects. The most common example of such moda...
Chemistry, Analysis, Pharmacokinetics and Pharmacodynamics Aspects of Lorcaserin, a Selective Serotonin 5-HT2C Receptor Agonist: An Update [0.03%]
lorcaserin选择性血清素5-ht2c受体激动剂的化学、分析、药动学和药效学研究进展
Sanjay Sharma,Komal S Aware,Ketan Hatware et al.
Sanjay Sharma et al.
This review refers to the all-inclusive details of Lorcaserin Hydrochloride on comprehensive information about the synthesis, analytical methods, pharmacodynamics, pharmacokinetics, drug interactions and adverse effects. Lorcaserin Hydrochl...
Exploring Signaling Pathways and Pancreatic Cancer Treatment Approaches Using Genetic Models [0.03%]
利用基因模型探索信号转导途径和胰腺癌治疗方法
Shorooq Khader,Anita Thyagarajan,Ravi P Sahu
Shorooq Khader
Despite available treatment options, the overall survival rates of pancreatic cancer patients remain dismal. Multiple counter-regulatory pathways have been identified and shown to be involved in interfering with the efficacy of therapeutic ...
Nurul Raudzah Adib Ridzuan,Norhashima Abd Rashid,Faizah Othman et al.
Nurul Raudzah Adib Ridzuan et al.
Cisplatin is a widely used antineoplastic agent for the treatment of metastatic tumors, advanced bladder cancer and many other solid tumors. However, at higher doses, toxicities such as nephrotoxicity may appear. Cisplatin leads to DNA dama...
Detoxification of Heterocyclic Aromatic Amines by Probiotic to Inhibit Medical Hazards [0.03%]
益生菌解毒杂环胺以抑制其致癌性医学危害研究进展
Kianoush Khosravi-Darani,F Barzegar,M Baghdadi
Kianoush Khosravi-Darani
Cancer is the second leading factor of human death in the world. Long-term consumption of cooked red meat brings about various types of cancers like colorectal cancer due to the formation of Heterocyclic Aromatic Amines (HAAs) during the he...
Malaria Hybrids: A Chronological Evolution [0.03%]
疟疾杂合体的 chronological evolution( chronologic evolution/chrono evolution):按照时间排序的进化过程或演变过程。
Akranth Marella,Garima Verma,Md Shaquiquzzaman et al.
Akranth Marella et al.
Malaria, an upsetting malaise caused by a diverse class of Plasmodium species affects about 40% of the world's population. The distress associated with it has reached colossal scales owing to the development of resistance to most of the cli...
Brain-eating Amoebae Infection: Challenges and Opportunities in Chemotherapy [0.03%]
食脑阿米巴感染的化疗挑战与机遇
Mohammad Ridwane Mungroo,Ayaz Anwar,Naveed Ahmed Khan et al.
Mohammad Ridwane Mungroo et al.
Pathogenic free-living amoeba are known to cause a devastating infection of the central nervous system and are often referred to as "brain-eating amoebae". The mortality rate of more than 90% and free-living nature of these amoebae is a cau...
Analysis of the Essential Oils of Five Artemisia Species and Evaluation of their Cytotoxic and Proapoptotic Effects [0.03%]
五种艾属植物精油的分析及其细胞毒性和促凋亡作用评估
Zahra Tayarani-Najaran,Maryam Akaberi,Bahareh Hassanzadeh et al.
Zahra Tayarani-Najaran et al.
Background: In this study, the essential oil composition and cytotoxic activities of five Artemisia species were determined. Methods: T...