Exploring Neurological Disorder Therapeutics: The Progress and Future Prospects of Proteins and Peptides Derived from Blue Foods [0.03%]
探究神经疾病治疗药物：来自“蓝色食物”的蛋白质和多肽的研究进展与未来前景
Mahima Chaudhary,Tushar Verma,Ravi Pratap Singh et al.
Mahima Chaudhary et al.
Introduction: Neurological illnesses continue to be a major global health challenge and require novel and safe therapeutic strategies. Blue foods like marine fish, algae, and invertebrates consist of many bioactive protei...
Significance of Proteomics in Cancer: Current Approaches and Trends in Biomarker Discovery [0.03%]
蛋白质组学在癌症中的意义：当前的生物标志物发现方法及趋势
Sonia Narwal,Minkal Tuteja
Sonia Narwal
Proteomic data, including protein identification, expression profiles, and modifications, have gained significant relevance in the molecular sciences. The mechanistic investigations on the growth and metastasis of tumours, for instance, can...
Therapeutic Peptides as Targeting Vectors and Smart Therapeutics: Emerging Trends and Future Perspectives [0.03%]
治疗肽作为靶向载体和智能药物：新兴趋势与未来展望
Ivana Valencia Ng,Sau Har Lee
Ivana Valencia Ng
Ever since the first monumental discovery in 1921, peptide science has evolved into the field of therapeutic peptides (TPs), whose unique biochemical properties bridge the gaps associated with small molecules and biologics. Despite the fasc...
Innovative Protein Nanostructures and Hybrid Systems for Enhanced Encapsulation and Controlled Delivery of Bioactive Agents [0.03%]
用于生物活性剂增强型封装和控制递送的创新性蛋白质纳米结构与杂化系统
Chandani Chandarana,Anandha Krishnan,Anjana Bera
Chandani Chandarana
Encapsulation technology is vital in food, pharmaceutical, and biomedical fields for protecting and delivering sensitive bioactive compounds. Proteins, due to their biocompatibility, biodegradability, and functional diversity, are increasin...
Nanotherapeutic Interventions in Diabetic Wound Healing: Biomarker- Guided Mechanisms and Translational Prospects [0.03%]
糖尿病伤口愈合的纳米治疗干预：生物标志物指导机制与转化前景
Pranjal Sachan,Jyotsana Dwivedi,Pranay Wal et al.
Pranjal Sachan et al.
Introduction: Diabetes mellitus is a chronic metabolic disorder that is frequently complicated by impaired wound healing, resulting in diabetic foot ulcers, amputations, and long-term disability. Conventional wound manage...
Recent developments in intein-mediated protein splicing and their applications in bioengineering [0.03%]
蛋白质内含肽介导的蛋白拼接研究进展及其生物工程应用
Zahra Rashidi Ghalamkhan,Safar Farajnia,Aydin Seirafi et al.
Zahra Rashidi Ghalamkhan et al.
Inteins are self-excising protein elements that catalyze their own removal from host polypeptides and mediate the ligation of the surrounding exteins, generating mature and functional proteins without the requirement for external cofactors ...
Vikash Poonia,Jay Kant Yadav
Vikash Poonia
Food Protein-derived Amyloid Fibrils (FPAFs) are rapidly gaining attention for their unique functional properties, offering new ways to improve texture and stability in plant-based and clean-label foods. These nanofibrils show superior gell...
Phosphodiesterase-5 Inhibitors in Neurodegenerative Diseases: A Path to Cognitive Rescue [0.03%]
磷二酯酶-5抑制剂在神经退行性疾病中的作用：认知恢复的新路径
Madhumitha Shankar,Prashant Tiwari,Sonal Dubey
Madhumitha Shankar
Phosphodiesterase type 5 inhibitors (PDE5-Is) have emerged as potential therapeutic agents for neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), and multiple sclerosis (MS). Originally developed for c...
Modulation of the Unfolded Protein Response by Viruses: Mechanistic Insights and Implications for viral Pathogenesis [0.03%]
病毒对未折叠蛋白反应的调控：机制见解及其对病毒病原学的意义
Jyoti Gupta,Istuti Saraswat
Jyoti Gupta
The endoplasmic reticulum (ER) is essential for protein synthesis, folding, maturation, transport, and calcium storage in mammalian cells. Perturbations in ER homeostasis, caused by stressors such as hypoxia, oxidative stress, or infection ...
Phα1β, a Peptide Derived from the Spider Phoneutria nigriventer, is a Potential New Antioxidant and Inflammation Modulator [0.03%]
来源于蜘蛛 Phoneutria nigriventer 的肽 Phα1β 是一种潜在的新抗氧化剂和炎症调节剂
José Augusto Nogueira-Machado,Fabiana Rocha-Silva,Debora Siqueira Jordão et al.
José Augusto Nogueira-Machado et al.
Background: The peptide Phα1β, derived from the venom of Phoneutria nigriventer, has been extensively investigated for its antinociceptive properties, primarily associated with modulation of ion channels and inflammator...