Modulation of the Unfolded Protein Response by Viruses: Mechanistic Insights and Implications for viral Pathogenesis
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The endoplasmic reticulum (ER) is essential for protein synthesis, folding, maturation, transport, and calcium storage in mammalian cells. Perturbations in ER homeostasis, caused by stressors such as hypoxia, oxidative stress, or infection result in the accumu... ...
