Prospective of Genomics in Revealing Transmission, Reassortment and Evolution of Wildlife-Borne Avian Influenza A (H5N1) Viruses [0.03%]
基因组学在揭示野生动物源禽流感病毒(A型H5N1亚型)传播、重配和进化中的前景
Fumin Lei,Weifeng Shi
Fumin Lei
The outbreak of highly pathogenic avian influenza (HPAI) H5N1 disease has led to significant loss of poultry and wild life and case fatality rates in humans of 60%. Wild birds are natural hosts for all avian influenza virus subtypes and ove...
Cristina Bozzao,Patrizia Lastella,Alessandro Stella
Cristina Bozzao
Lynch syndrome (LS) is the most common form of inherited predisposition to develop cancer mainly in the colon and endometrium but also in other organ sites. Germline mutations in DNA mismatch repair (MMR) gene cause the transmission of the ...
Irene Gazquez,Jose A Lopez-Escamez
Irene Gazquez
We present recent advances in the genetics of recurrent vertigo, including familial episodic ataxias, migraneous vertigo, bilateral vestibular hypofunction and Meniere's disease.Although several vestibular disorders are more common within f...
Life or death? A physiogenomic approach to understand individual variation in responses to hemorrhagic shock [0.03%]
生理基因组方法研究出血性休克的个体差异响应
Harold G Klemcke,Bina Joe,Rajiv Rose et al.
Harold G Klemcke et al.
Severe hemorrhage due to trauma is a major cause of death throughout the world. It has often been observed that some victims are able to withstand hemorrhage better than others. For decades investigators have attempted to identify physiolog...
Proteases in malaria parasites - a phylogenomic perspective [0.03%]
疟原虫的蛋白酶-基于谱系遗传的观点研究蛋白质编码基因和基因组特征
Hong Cai,Rui Kuang,Jianying Gu et al.
Hong Cai et al.
Malaria continues to be one of the most devastating global health problems due to the high morbidity and mortality it causes in endemic regions. The search for new antimalarial targets is of high priority because of the increasing prevalenc...
Zhan Zhou,Jianying Gu,Yi-Ling Du et al.
Zhan Zhou et al.
Streptomyces is a group of soil bacteria of medicinal, economic, ecological, and industrial importance. It is renowned for its complex biology in gene regulation, antibiotic production, morphological differentiation, and stress response. In...
Microbial metabolomics [0.03%]
微生物代谢组学
Jane Tang
Jane Tang
Microbial metabolomics constitutes an integrated component of systems biology. By studying the complete set of metabolites within a microorganism and monitoring the global outcome of interactions between its development processes and the en...
Highly efficient proteolysis accelerated by electromagnetic waves for Peptide mapping [0.03%]
电磁波加速的高效蛋白质降解用于肽图鉴定
Qiwen Chen,Ting Liu,Gang Chen
Qiwen Chen
Proteomics will contribute greatly to the understanding of gene functions in the post-genomic era. In proteome research, protein digestion is a key procedure prior to mass spectrometry identification. During the past decade, a variety of el...
Evolutionary systems biology [0.03%]
进化系统生物学
Jianying Gu
Jianying Gu
Guy Drouin,Jean-Rémi Godin,Benoît Pagé
Guy Drouin
Vitamin C (ascorbic acid) plays important roles as an anti-oxidant and in collagen synthesis. These important roles, and the relatively large amounts of vitamin C required daily, likely explain why most vertebrate species are able to synthe...