Comparison of models for the collinearity of hox genes in the developmental axes of vertebrates [0.03%]
脊椎动物发育轴HOX基因共线性模型比较研究进展
Spyros Papageorgiou
Spyros Papageorgiou
Hox gene clusters are very frequent in many animal genomes and their role in development is pivotal. Particularly in vertebrates, intensive efforts have established several properties of Hox clusters. The collinearity of Hox gene expression...
Jose Crossa
Jose Crossa
Historically in plant breeding a large number of statistical models has been developed and used for studying genotype × environment interaction. These models have helped plant breeders to assess the stability of economically important trai...
Human complex trait genetics: lifting the lid of the genomics toolbox - from pathways to prediction [0.03%]
人类复杂性状遗传学：开启基因组学工具箱之门——从通路到预测
Suzanne J Rowe,Albert Tenesa
Suzanne J Rowe
During the initial stages of the genome revolution human genetics was hugely successful in discovering the underlying genes for monogenic diseases. Over 3,000 monogenic diseases have been discovered with simple patterns of inheritance. The ...
Jack C M Dekkers
Jack C M Dekkers
The main goal in animal breeding is to select individuals that have high breeding values for traits of interest as parents to produce the next generation and to do so as quickly as possible. To date, most programs rely on statistical analys...
William G Hill
William G Hill
The genetic analysis of quantitative or complex traits has been based mainly on statistical quantities such as genetic variances and heritability. These analyses continue to be developed, for example in studies of natural populations. Genom...
A M Pérez-de-Castro,S Vilanova,J Cañizares et al.
A M Pérez-de-Castro et al.
Plant breeding has been very successful in developing improved varieties using conventional tools and methodologies. Nowadays, the availability of genomic tools and resources is leading to a new revolution of plant breeding, as they facilit...
Bernardo Ordas
Bernardo Ordas
Current applications of models of genetic effects with interactions across the genome [0.03%]
全基因组互作的遗传效应模型的当前应用
José M Alvarez-Castro
José M Alvarez-Castro
Models of genetic effects integrate the action of genes, regulatory regions and interactions among alleles across the genome. Such theoretical frameworks are critical for applied studies in at least two ways. First, discovering genetic netw...
Chitra Dutta,Sandip Paul
Chitra Dutta
Microbes are known for their unique ability to adapt to varying lifestyle and environment, even to the extreme or adverse ones. The genomic architecture of a microbe may bear the signatures not only of its phylogenetic position, but also of...
Bibekanand Mallick,Zhumur Ghosh
Bibekanand Mallick
Intergenic DNA, often described as "playground of evolution", harbors a plethora of cis and trans regulatory elements in the form of non-coding RNAs (ncRNAs). The evolution of the silencing mechanism mediated by microRNAs (miRNAs), an impor...