Magnetic Nanoparticles: Properties, Synthesis and Biomedical Applications [0.03%]
磁性纳米颗粒:性能、合成与生物医学应用
Salman Khan,Syed Mohd Danish Rizvi,Varish Ahmad et al.
Salman Khan et al.
Importance of magnetic nanoparticles in daily life including biomedical applications in near future cannot be overlooked. This review focuses on the properties of magnetic nanoparticles (MNPs), various approaches for their synthesis, and th...
Emerging Strategies and Challenges for Controlled Delivery of Taxanes: A Comprehensive Review [0.03%]
紫杉醇类药物控制释放的现状、挑战及展望:综述
Mohit Mahajan,Rajneet Kaur Khurana,Nikhil Shri Sahajpal et al.
Mohit Mahajan et al.
Taxanes introduction in the mid 90 s leads to significant advancement as well as superlative improvement in the treatment of cancer. Since then, several strategies have been designed to enhance therapeutic potential of these agents by overc...
Diallyl Sulfide: Potential Use in Novel Therapeutic Interventions in Alcohol, Drugs, and Disease Mediated Cellular Toxicity by Targeting Cytochrome P450 2E1 [0.03%]
二丙基硫化物:通过靶向细胞色素P450 2E1用于酒精、药物和疾病介导的细胞毒性新型治疗干预的潜在作用研究
P S S Rao,Narasimha M Midde,Duane D Miller et al.
P S S Rao et al.
Diallyl sulfide (DAS) and other organosulfur compounds are chief constituents of garlic. These compounds have many health benefits, as they are very efficient in detoxifying natural agents. Therefore, these compounds may be useful for preve...
Adverse Drug Reactions to Anti-TB Drugs: Pharmacogenomics Perspective for Identification of Host Genetic Markers [0.03%]
药物基因omic视角下的抗结核病药物不良反应及宿主遗传标志物识别
Roshan Kumar Sahu,Kan Singh,Swati Subodh
Roshan Kumar Sahu
Adverse drug reactions (ADRs) are associated with clinical morbidity and, in severe cases, even mortality. Globally billions of dollars are spent on managing these ADRs for common and uncommon diseases. The developing world suffers from a h...
Physiologically Based In vitro Models to Predict the Oral Dissolution and Absorption of a Solid Drug Delivery System [0.03%]
基于生理的体外模型预测固体药物递送系统口服溶出和吸收
Ziqiang Li,Xin He
Ziqiang Li
To understand the sophisticated dynamic behaviors of drug elution and permeation in the gastrointestinal tract (GIT), researchers have tried to reemerge it by employing various in vitro experimental models. However, official in vitro appara...
Luning Zhuang,Huiming Xia,Yuan Gu et al.
Luning Zhuang et al.
The major aim of current pharmacokinetic studies is to investigate the drug absorption, disposition, metabolism and excretion in animals and humans. The time courses of plasma concentrations are usually characterized and linked to the pharm...
Interactions between Transporters and Herbal Medicines/Drugs: A Focus on Hepatoprotective Compounds [0.03%]
转运体与中药/药物的相互作用及护肝活性化合物研究:focus on hepatoprotective compounds
Aijie Zhang,Quansheng Li,Xin He et al.
Aijie Zhang et al.
Many herbal medicines and drugs are available in the clinic as potent hepatoprotective agents for the treatment of commonly occurring liver diseases. Recently, herbal medicines such as silymarin and curcumin have gained more attention and p...
Yuan-Sheng Zhao,Chuan Li
Yuan-Sheng Zhao
In the past decade, mass spectrometry imaging (MSI) has received an increasing amount of attention due to its ability in displaying the spatial distribution of a wide range of molecules, including peptides, proteins, lipids, endogenous and ...
Characterization of fungal and bacterial components in gut/fecal microbiome [0.03%]
肠道/粪便微生物组中真菌和细菌成分的特征分析
Roland Kirschner,Tien Hsu,Nguyen Ngoc Tuan et al.
Roland Kirschner et al.
The gut microbiota is a complex ecosystem that affects the development, nutritional status and immunological responses of the host. Prokaryotes and fungi in the community have the abilities to withstand the adverse conditions of high temper...
Propionibacterium acnes in the pathogenesis and immunotherapy of acne vulgaris [0.03%]
丙酸杆菌痤疮素在寻常痤疮发病机制和免疫治疗中的作用
Pei-Feng Liu,Yao-Dung Hsieh,Ya-Ching Lin et al.
Pei-Feng Liu et al.
Acne vulgaris, a multi-factorial disease, is one of the most common skin diseases, affecting an estimated 80% of Americans at some point during their lives. The gram-positive and anaerobic Propionibacterium acnes (P. acnes) bacterium has be...