Nrf2 Regulates the Expression of CYP2D6 by Inhibiting the Activity of Krüppel-Like Factor 9 (KLF9) [0.03%]
Nrf2通过抑制Krüppel样因子9(KLF9)的活性调控CYP2D6的表达
Ferbian Milas Siswanto,Maria Dara Novi Handayani,Rita Dewi Firmasyah et al.
Ferbian Milas Siswanto et al.
Aims: The aim of the present study is to gain insight into the biology of Parkinson's disease (PD) and cancer to drive translational advances enabling more effective prevention and/or potential treatments. ...
Pharmacokinetics and Tissue Distribution of Isovitexin-2''-O-β-D-glucopyranoside (IVG) in Sprague-Dawley Rats [0.03%]
异薇.tex苷的药代动力学及组织分布研究
Xiaotong Zhao,Leilei Fang,Tan Yang et al.
Xiaotong Zhao et al.
Background: Isovitexin-2"-O-D-glucopyranoside (IVG) has been known to exhibit sedative and hypnotic effects. However, there is little understanding of the in vivo pharmacokinetics and tissue distribution of IVG. ...
Factors Influencing ADME Properties Of Drugs: Advances and Applications (Part II) [0.03%]
影响药物ADME属性的因素：进展与应用（第二部分）
Shuang-Qing Zhang,Feng Chen
Shuang-Qing Zhang
Comprehensive Investigation of the Influence of High-Altitude Hypoxia on Clopidogrel Metabolism and Gut Microbiota [0.03%]
高原低氧对氯吡格雷代谢和肠道菌群的影响研究
Juanhong Zhang,Yuemei Sun,Jiaxin He et al.
Juanhong Zhang et al.
Background: The amount of metabolites converted into active metabolites is correspondingly reduced since only more than 50% of clopidogrel is absorbed. Ob...
Corrigendum: Intracellular Delivery: Exploiting Viral Membrane Topic Peptide [0.03%]
更正： intracellular delivery: 开发利用病毒膜主题肽
Stefania Galdiero,Mariateresa Vitiello,Annarita Falanga et al.
Stefania Galdiero et al.
The authors declare that after the publication of the article, it was noticed that two citations were inadvertently omitted. The references have now been included as [74b] and [74c]: [74] (b) Vitiello, M.; Galdiero, M.; Galdiero, M. Inhibit...
Artificial Intelligence in Drug Formulation and Development: Applications and Future Prospects [0.03%]
人工智能在药物配方和开发中的应用及未来前景
Noorain,Varsha Srivastava,Bushra Parveen et al.
Noorain et al.
Artificial Intelligence (AI) has emerged as a powerful tool in various domains, and the field of drug formulation and development is no exception. This review article aims to provide an overview of the applications of AI in drug formulation...
Shaojingya Gao,YunFeng Lin
Shaojingya Gao
The Influence of Atorvastatin, Amlodipine and Ethoxidol on Ubiquinol and Ubiquinone Endogenous Plasma Concentrations in Patients with Chronic Heart Failure [0.03%]
阿托伐他丁、氨氯地平和乙氧化醇对慢性心力衰竭患者血浆内源性辅酶Q_(10)和辅酶Q_(10)浓度的影响
V I Zozina,S N Kondratenko,E V Shikh et al.
V I Zozina et al.
Background: Coenzyme Q10 is a key component of the mitochondrial respiratory chain and a fat-soluble endogenous antioxidant performing many vital functions in the human body. Many researchers studied the plasma concentrat...
Which can Predict the Outcome of Antidepressants: Metabolic Genes or Pharmacodynamic Genes? [0.03%]
代谢基因和药理动力学基因哪一个能预测抗抑郁药物的疗效？
Nan Zheng,Mengxi Niu,Yannan Zang et al.
Nan Zheng et al.
Drug therapy is the primary modality for depression; however, its outcome is often unpredictable, ranging from beneficial effects to serious adverse effects. Genetic variations in drug metabolizing enzymes and pharmacodynamic molecules are ...
Su Zeng,Huichang Bi,Eric Chun Yong Chan
Su Zeng