Lignans and diterpenes isolated from Tirpitzia ovoidea and their biological activities [0.03%]
Tirpitzia ovoidea中分离的木脂素和二萜及其生物活性
Xue-Yan Yang,Yi-Fan Zhang,Li-Jia Liu et al.
Xue-Yan Yang et al.
A new lignan, tirpitzin A (17) together with 20 known compounds (1-16, and 18-21) were isolated from the ethyl acetate soluble fraction of ethanol extract of the aerial parts of Tirpitzia ovoidea. The structure of new compound was elucidate...
Synthesis and anti-hepatocellular carcinoma activity of novel O2-vinyl diazeniumdiolate-based nitric oxide-releasing derivatives of oleanolic acid [0.03%]
新的O2-乙烯叠氮化二醇酯类没食子酸释放硝基化合物的合成及其抗肝癌活性研究
Yu Zou,Chang Yan,Jing-Chao Liu et al.
Yu Zou et al.
Considering that high levels of nitric oxide (NO) exert anti-cancer effect and the derivatives of oleanolic acid (OA) have shown potent anti-cancer activity, new O2-vinyl diazeniumdiolate-based NO releasing derivatives (5a-l, 11a-l) of OA w...
HPPR encodes the hydroxyphenylpyruvate reductase required for the biosynthesis of hydrophilic phenolic acids in Salvia miltiorrhiza [0.03%]
HPPR编码丹参羟基苯丙酮酸还原酶该酶是水溶性茋类化合物生物合成的必需酶
Guo-Quan Wang,Jun-Feng Chen,Bo Yi et al.
Guo-Quan Wang et al.
Salvia miltiorrhiza is a medicinal plant widely used in the treatment of cardiovascular and cerebrovascular diseases. Hydrophilic phenolic acids, including rosmarinic acid (RA) and lithospermic acid B (LAB), are its primary medicinal ingred...
Preparation and physicochemical characterization of T-OA PLGA microspheres [0.03%]
T-OA-PLGA微球的制备及其理化表征研究
Jing Fu,Xiao-Xu Dong,Zu-Ping Zeng et al.
Jing Fu et al.
As the carrier of water-insoluble drugs, microspheres can play a role in increasing solubility and delaying releasing essence. The objective of this study was to improve the solubility and to delay the release of a newly discovered antitumo...
Atractylodes lancea rhizome water extract reduces triptolide-induced toxicity and enhances anti-inflammatory effects [0.03%]
苍术根水提取物减轻三氧茋毒副作用并增强其抗炎作用
Yuan Wei,Dan-Juan Sui,Hai-Miao Xu et al.
Yuan Wei et al.
The present study was designed to explore the influence of water extracts of Atractylodes lancea rhizomes on the toxicity and anti-inflammatory effects of triptolide (TP). A water extract was prepared from A. lancea rhizomes and co-administ...
Effects of Gardenia jasminoides extracts on cognition and innate immune response in an adult Drosophila model of Alzheimer's disease [0.03%]
结香提取物对阿尔茨海默病成年果蝇模型认知和先天性免疫反应的影响
Wei-Wei Ma,Ye Tao,Yan-Ying Wang et al.
Wei-Wei Ma et al.
Herbal extracts have been extensively used worldwide for their application on memory improvement, especially among aged and memory-deficit populations. In the present study, the memory loss induced by human Abeta protein over-expression in ...
Polysaccharides extracted from the roots of Bupleurum chinense DC modulates macrophage functions [0.03%]
防风草根多糖具有调节巨噬细胞的功能
Zhi-De Zhang,Hong Li,Fen Wan et al.
Zhi-De Zhang et al.
The present study aimed to investigate the effects of polysaccharides extracted from Bupleurum chinense DC (BCPs) on macrophage functions. In the in vivo experiment, 1 mL of 5% sodium thioglycollate was injected into the abdomen of the mice...
Anticancer carbazole alkaloids and coumarins from Clausena plants: A review [0.03%]
来源于 Clausena 属植物的抗肿瘤咔唑生物碱和香豆素类成分研究进展
Li Huang,Zhe-Ling Feng,Yi-Tao Wang et al.
Li Huang et al.
Pharmaceutical research has focused on the discovery and development of anticancer drugs. Clinical application of chemotherapy drugs is limited due to their severe side effects. In this regard, new naturally occurring anticancer drugs have ...
Synthesis and cytotoxicity evaluation of 3-amino-2-hydroxypropoxygenistein derivatives [0.03%]
3-氨基-2-羟基丙 oxyistein衍生物的合成及细胞毒性评价
Xiao-Ting Geng,Jing-Jing Tang,Kun-Peng Cheng et al.
Xiao-Ting Geng et al.
Soy isoflavones exhibit various biological activities, such as antioxidant, anti-tumor, anti-inflammatory, and cardiovascular protective effects. The present study was designed to investigate the effects of sixteen synthesized 3-amino-2-hyd...
Bioassay-guided isolation of novel and selective urease inhibitors from Diospyros lotus [0.03%]
基于生物测定的梾木中新型选择性脲酶抑制剂的分离研究
Abdur Rauf,Ghias Uddin,Bina S Siddiqui et al.
Abdur Rauf et al.
Two new dimeric naphthoquinones, 5',8'-dihydroxy-6,6'-dimethyl-7,3'-binaphthyl-1,4,1',4'-tetraone (1; Di-naphthodiospyrol D) and 5',8'-dihydroxy-5,8-dimethoxy-6,6'-dimethyl-7,3'-binaphthyl-1,4,1',4'-tetraone (2; Di-naphthodiospyrol E), alon...