A pair of cyclopeptide epimers from the seeds of Celosia argentea [0.03%]
Celosia argentea种子中的两个环肽异构体
Feng-Jie Liu,Zhi-Hua Zhu,Yan Jiang et al.
Feng-Jie Liu et al.
Two cyclopeptides, celogentin L (1) and its epimer lyciumin A (2) were firstly isolated from Celosia argentea L.. The planar structures of the two compounds were fully determined by spectroscopic data, including 1D-, 2D-NMR, and HR-ESI/MS. ...
Network pharmacology-based analysis of Chinese herbal Naodesheng formula for application to Alzheimer's disease [0.03%]
基于网络药理学的中药脑心康制剂治疗阿尔茨海默病的应用分析
Xiao-Cong Pang,De Kang,Jian-Song Fang et al.
Xiao-Cong Pang et al.
Naodesheng (NDS) formula, which consists of Rhizoma Chuanxiong, Lobed Kudzuvine, Carthamus tinctorius, Radix Notoginseng, and Crataegus pinnatifida, is widely applied for the treatment of cardio/cerebrovascular ischemic diseases, ischemic s...
Puerarin attenuates angiotensin II-induced cardiac fibroblast proliferation via the promotion of catalase activity and the inhibition of hydrogen peroxide-dependent Rac-1 activation [0.03%]
葛根素通过促进过氧化氢酶活性和抑制H2O2依赖的Rac-1活化来减轻血管紧张素II诱导的心脏成纤维细胞增殖作用
Gang Chen,Shi-Fen Pan,Xiang-Li Cui et al.
Gang Chen et al.
The aims of the present study were to evaluate the effects of puerarin on angiotensin II-induced cardiac fibroblast proliferation and to explore the molecular mechanisms of action. Considering the role of H2O2 in nicotinamide adenine dinucl...
Saponins isolated from Schizocapsa plantaginea inhibit human hepatocellular carcinoma cell growth in vivo and in vitro via mitogen-activated protein kinase signaling [0.03%]
牻牛儿苗中分离得到的皂苷通过丝裂原活化蛋白激酶信号抑制人肝癌细胞的生长
Yue-Wen Sun,Han-Chen Qiu,Ming-Chun Ou et al.
Yue-Wen Sun et al.
The underground cane of Schizocapsa plantaginea (Hance) has long been used by Chinese ethnic minority as a constituent of anti-cancer formulae. Saponins are abundant secondary metabolic products located in the underground cane of this plant...
Reversal of multidrug resistance by icaritin in doxorubicin-resistant human osteosarcoma cells [0.03%]
(icaritin逆转人骨肉瘤多药耐药细胞株耐药性的作用研究)
Zhen-Dong Wang,Rui-Zhi Wang,Yuan-Zheng Xia et al.
Zhen-Dong Wang et al.
Multidrug resistance (MDR) is one of the major obstacles in cancer chemotherapy. Our previous study has shown that icariin could reverse MDR in MG-63 doxorubicin-resistant (MG-63/DOX) cells. It is reported that icariin is usually metabolize...
Cucurbitacin B suppresses metastasis mediated by reactive oxygen species (ROS) via focal adhesion kinase (FAK) in breast cancer MDA-MB-231 cells [0.03%]
cucurbitacin B通过黏着斑激酶(FAK)抑制乳腺癌MDA-MB-231细胞介导的活性氧(ROS)转移作用
Wei-Wei Luo,Wen-Wen Zhao,Jin-Jian Lu et al.
Wei-Wei Luo et al.
Metastasis is responsible for the majority of cancer-related deaths and prevention of metastasis remains a big challenge for cancer therapy. Cucurbitacin B (Cuc B) is a natural triterpenoid with potent anticancer activities while its effect...
Molecular diversity analysis of Tetradium ruticarpum (WuZhuYu) in China based on inter-primer binding site (iPBS) markers and inter-simple sequence repeat (ISSR) markers [0.03%]
基于引物对结合位点和简单序列重复区间多态性分析吴茱萸的分子多样性研究
Jing-Yuan Xu,Yan Zhu,Ze Yi et al.
Jing-Yuan Xu et al.
"Wu zhu yu", which is obtained from the dried unripe fruits of Tetradium ruticarpum (A. Jussieu) T. G. Hartley, has been used as a traditional Chinese medicine for treatment of headaches, abdominal colic, and hypertension for thousands of y...
Comparative Study
Chinese journal of natural medicines. 2018 Jan;16(1):1-9. DOI:10.1016/S1875-5364(18)30024-4 2018
UHPLC-LTQ-Orbitrap-based metabolomics coupled with metabolomics pathway analysis method for exploring the protection mechanism of Kudiezi injection in a rat anti-ischemic cerebral reperfusion damage model [0.03%]
基于UHPLC-LTQ-Orbitrap代谢组学结合代谢通路分析方法探究葵花子注射液抗脑缺血再灌注损伤的保护机制
Si-Yi Liu,Wei Cai,Fei Wang et al.
Si-Yi Liu et al.
Kudiezi injection has been used extensively in the treatment of cerebrovascular and cardiovascular diseases. However, its therapeutic effects and underlying mechanism of action are not fully understood. The aim of the present study was to c...
Cycloartane triterpenoid and its glucoside isolated from Cassia occidentalis [0.03%]
簇蕊莲苦木素环三萜及其糖苷分离鉴定研究
Shi-Fei Li,Shun-Lin Li
Shi-Fei Li
In the present study, one new cycloartane triterpenoid, named cycloccidentalic acid C (1) and its glucoside, cycloccidentaliside VI (2) were isolated from the whole plant of Cassia occidentalis. Their structures were elucidated by a combina...
Three new anthraquinone derivatives isolated from Symplocos racemosa and their antibiofilm activity [0.03%]
Symplocos racemosa的新蒽醌类衍生物及其抗生物被膜活性研究
Umar Farooq,Sara Khan,Sadia Naz et al.
Umar Farooq et al.
Three new alkyl substituted anthraquinone derivatives, trivially named as symploquinones A-C (Compounds 1-3) were isolated from Symplocos racemosa. The structures of these compounds were determined on the basis of extensive spectroscopic an...