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Reversal of multidrug resistance by icaritin in doxorubicin-resistant human osteosarcoma cells

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Multidrug resistance (MDR) is one of the major obstacles in cancer chemotherapy. Our previous study has shown that icariin could reverse MDR in MG-63 doxorubicin-resistant (MG-63/DOX) cells. It is reported that icariin is usually metabolized to icariside II an... ...