The Impact of IGFBP6 Knockdown on Cholesterol Metabolism in Breast Cancer Cells [0.03%]
IGFBP6敲低对乳腺癌细胞胆固醇代谢的影响
Ivan Denisovich Antipenko,Julia Alekseevna Makarova,Maxim Yurievich Shkurnikov et al.
Ivan Denisovich Antipenko et al.
Introduction: Cholesterol plays a key role in maintaining tumor cell homeostasis. Reduced IGFBP6 expression is associated with an increased risk of breast cancer recurrence. Previous studies showed that IGFBP6 knockdown d...
Harnessing Vitamin C: Unveiling Its Potential in Cancer Prevention and Treatment [0.03%]
利用维生素C：揭示其在癌症预防和治疗中的潜力
Antara Roy,Dilip K Maiti,Bimal Krishna Banik
Antara Roy
The strong antioxidant vitamin C has been researched for its potential use in the prevention and treatment of cancer. Scavenging free radicals and lowering oxidative stress, which is essential in carcinogenesis, helps to protect cells. Exce...
MiRNA Regulations in Cardiotoxicity Induced by Oncologic Therapies and Possible Immune Response [0.03%]
肿瘤治疗引起的心脏毒性中的微RNA调控及可能的免疫反应
Desh Deepak Singh
Desh Deepak Singh
Anti-cancer therapy offers significant risks for cardiovascular diseases, including hypertension, thromboembolic ischaemia, arrhythmias, dyslipidaemia, hyperglycemia, obesity, and high cholesterol. Cardiotoxicity is a leading cause of eleva...
Medical Artificial Intelligence: Opportunities and Challenges In Infectious Disease Management [0.03%]
医疗人工智能：传染病管理中的机遇与挑战
Ankit Sahoo,Janhvi Singh,Kainat Alam et al.
Ankit Sahoo et al.
Globally, millions of individuals suffer from infectious diseases, which are major public health concerns caused by bacteria, fungi, viruses, or parasites. These diseases can be transmitted directly or indirectly from person to person, pote...
New Indazole Derivatives as Potential Scaffolds for the Development of Anticancer, Antiviral, and Anti-tuberculosis Chemotherapeutic Compounds [0.03%]
新型吲唑衍生物作为抗癌、抗病毒和抗结核化疗药物的潜在骨架
Khandazhinskaya Anastasia,Kondrashova Evgenya,Sokhraneva Vera et al.
Khandazhinskaya Anastasia et al.
Introduction: Chemotherapy remains essential despite advances in immunotherapy, radiotherapy, and biological therapy. However, the wide range of chemical drugs is limited by a narrow therapeutic index, low selectivity, an...
Mechanisms of Inflammation Chronification: Genetic and Epigenetic Regulation of Intolerant Response (Trained Immunity) [0.03%]
炎症慢性化的机制：不耐受反应（训练免疫）的遗传及表观遗传调控
Alexander Nikolaevich Orekhov,Andrey Vladimirovich Omelchenko,Alexander Dmitrievich Zhuravlev et al.
Alexander Nikolaevich Orekhov et al.
Diagnosis and Potential Therapy of Brain Diseases Using 64Cu: A Scoping Review [0.03%]
应用64Cu诊断和治疗脑部疾病的研究进展：综述性文章
Yumei An,Xinqi Huang,Mingyuan Xu et al.
Yumei An et al.
Introduction: This paper provides a comprehensive review examining the application of copper radionuclides, particularly 64Cu, in the diagnosis and potential therapy of various brain diseases. ...
Gyas Khan,Sarfaraz Ahmad,Md Sadique Hussain
Gyas Khan
Triple-Negative Breast Cancer (TNBC) is defined as a type of breast cancer having the absence of estrogen, progesterone, and human epidermal growth factor receptors. So far, chemotherapeutic drugs and immunotherapy have several issues, such...
Arshleen Kaur,Rajesh K Singh,Rohit Bhatia
Arshleen Kaur