Natural Protein and Lipid Carriers as Food Grade Nanocages for Delivering Bioactive Compounds with Improved Therapeutic Efficacy: A Review [0.03%]
基于食物级纳米笼的生物活性物质高效传输体系构建及其递送机制研究综述
Priya Patel,Kevin Kumar Garala,Sudarshan Singh et al.
Priya Patel et al.
Scientists have been keenly interested in using bioactive compounds as food supplements over the past few decades. Nevertheless, such components frequently show low stability, and solubility, and limited gastrointestinal tract bio accessibi...
Nikita G Nikiforov
Nikita G Nikiforov
Approaches to Scaffold Hopping for Identifying New Bioactive Compounds and the Contribution of Artificial Intelligence [0.03%]
绕过支架识别新活性化合物的方法及人工智能的贡献
Milainy Rocha Viana,Ana Claudia Beneton Galeriani,Wanda Pereira Almeida
Milainy Rocha Viana
The failure of a potential drug in the clinical study phase represents a significant cost and a loss of time for the process. Therefore, the development of strategies that can increase efficiency, streamline efforts, and lower expenses has ...
A Comprehensive Review on Promising Herbal Drug Discovery for Breast Cancer Management [0.03%]
用于乳腺癌管理的 promising herbal drug发现的全面回顾
Adwitiya Banerjee,Shivnath Banerjee,Anil Kumar Singh et al.
Adwitiya Banerjee et al.
Breast cancer is one of the most prevalent and life-threatening cancers globally. For the treatment of breast cancer, the exploration of novel therapeutic strategies is essential. Recent advances in herbal drug discovery have garnered signi...
Research Progress on the Application of Ultrasound Assistance in Tumor Immunotherapy [0.03%]
超声在肿瘤免疫治疗中的应用研究进展
Lu Yao Fan,Hui Yu,Li Wen Cui et al.
Lu Yao Fan et al.
Recently, ultrasound (US)-assisted tumor immunotherapy has attracted widespread attention due to its deep penetration as well as its non-invasive and non-ionizing radiation properties. In this review, we briefly elucidated the mechanisms of...
Potential Targets and Mechanism of Action of Wangwei Powder in Tic Disorder Therapy: Bioinformatics and Network Pharmacology Analyses [0.03%]
王威堂颗粒治疗抽动障碍的潜在靶点及作用机制：生物信息学与网络药理学分析
Haijiao Lin,Yiquan Li,Liping Sun et al.
Haijiao Lin et al.
Introduction: Tic disorders are neuropsychiatric conditions characterized by involuntary motor or vocal tics; however, the mechanisms underlying these disorders and potential therapeutic targets remain unknown. Therefore,...
A Bi-directional Mendelian Randomization Study of Idiopathic Pulmonary Fibrosis and Six Diabetes-related Traits [0.03%]
特发性肺纤维化和六种与糖尿病相关特征的双向孟德尔随机化研究
Yi Nie,Hongmei Li,Haibin Wang
Yi Nie
Introduction: The objective of the present study was to explore the bi-directional causal relationship between IPF and diabetes (type 1 diabetes and type 2 diabetes)/ diabetic nephropathy/glycemic traits [fasting glucose ...
Identification and Validation of NDRG2 as a Biomarker for Follicular Lymphoma [0.03%]
NDRG2作为滤泡性淋巴瘤生物标志物的鉴定与验证
Yidong Zhu,Jun He,Rong Wei
Yidong Zhu
Introduction: Follicular lymphoma (FL) is the most prevalent form of indolent lymphoma, characterized by intermittent relapse and remission periods. This study aims to identify potential biomarker genes for FL and elucida...
Multi-Omics and Mendelian-Randomization Investigation of Mitochondrial Genes in Irritable Bowel Syndrome [0.03%]
综合多组学和孟德尔随机化研究肠易激综合征的线粒体基因作用
Beibei Xu,Ji Zhang,Yi Huang et al.
Beibei Xu et al.
Introduction: This study aimed to explore potential causal relationships between mitochondria- related genes and irritable bowel syndrome (IBS) using integrative multi-omics analysis. ...
Integrated Bioinformatic Analysis of the Shared Molecular Mechanisms Between Osteoporosis and Aortic Stenosis [0.03%]
骨质疏松和主动脉瓣狭窄之间的共享分子机制的综合生物信息学分析
Yue-Jiao Yang,Yang He,Zhao-Wei Zhu et al.
Yue-Jiao Yang et al.
Introduction: Osteoporosis (OP) and aortic stenosis (AS) are highly prevalent age-related disorders that frequently coexist. Epidemiological studies suggest a pathological link between OP and AS beyond age, yet the molecu...