Mechanistic Insights into the Ferroptosis-Regulating Effects of EF in the Treatment of Chronic Renal Failure [0.03%]
EF治疗慢性肾衰竭的铁死亡调节作用机制研究新进展
Qian Zhang,Xinran Xv,Wanchuan Zhang et al.
Qian Zhang et al.
Introduction: Chronic Renal Failure (CRF) is a progressive disease that severely affects patients' quality of life, but its current treatment options remain limited. This study explores the potential mechanism of Eriobotr...
Asiya Kurmanova,Dieter Riethmacher
Asiya Kurmanova
Rheumatoid arthritis is a chronic autoimmune disorder affecting approximately 230 per 100,000 people worldwide. It typically affects joints and bones but may involve other tissues and internal organs as well. Rheumatoid arthritis is twice a...
CD47-SIRPα: A Pivotal Signaling Pathway for Targeting Immunotherapy in Non-Small Cell Lung Cancer [0.03%]
CD47-SIRPα:非小细胞肺癌免疫治疗靶向的關鍵信號通路
Luying Zhang,Xueqin Wu,Mingyue Zhu et al.
Luying Zhang et al.
Non-Small Cell Lung Cancer (NSCLC) remains a major oncologic challenge with high mortality. The CD47-SIRPα pathway is critical for tumor immune escape by mediating "don't eat me" signaling. Despite progress, the specific mechanism of actio...
Exploring the Potential of Nuciferine in Diabetes Management via PTGS2 Pathway Targeting by Network Analysis and in Silico Modeling Approach [0.03%]
基于网络药理学和分子对接研究睡莲素防治糖尿病的机制探讨
N Sridevi,Thirumal Margesan
N Sridevi
Introduction: Diabetes mellitus, a chronic metabolic disorder characterized by elevated blood glucose levels, has emerged as a significant global health burden. Chronic inflammation and insulin resistance are central to t...
Comprehensive Pan-cancer analysis of Pyroglutamylated RFamide Peptide Receptor: Its Potential Biological Functions and Associations with Prognosis and Immunity [0.03%]
泛癌分析焦谷氨酰RF胺肽受体:其潜在的生物学功能及其与预后和免疫的关系
Quanxin Huang,Boyuan Qiu,Tiantian Lu et al.
Quanxin Huang et al.
Introduction: The receptor for pyroglutamylated RF amide peptide (QRFPR) is a G protein-coupled receptor that plays a role in various physiological and pathological processes. However, a gap remains in our understanding o...
A Unified Model of Consciousness: Glycoprotein Patterns in Memory Processes and Quantum Entanglement [0.03%]
意识的统一模型:记忆过程中的糖蛋白模式与量子纠缠
Atta-Ur-Rahman
Atta-Ur-Rahman
The author had previously proposed that memory could be encoded as patterns of hydrogen-bonded "frozen" conformers of neuronal glycoproteins. These stabilised molecular patterns represent an ideal template for information storage in the hum...
The Emerging Role of N-Acetylcysteine in Psychiatry: A Narrative Review of Available Data [0.03%]
N-乙酰半胱氨酸在精神病学中的新兴作用:现有数据的叙述性综述
Donatella Marazziti,Valerio Caruso,Gabriele Cappellato et al.
Donatella Marazziti et al.
N-acetylcysteine (NAC), a cysteine derivative with a reactive thiol group, possesses antioxidant and anti-inflammatory properties. Its redox activity plays a central role in scavenging reactive oxygen and nitrogen species and modulating cel...
Retraction Notice to Single-cell RNA-sequencing Analysis Reveals the Promoting Role of the Hedgehog Pathway in Epithelial Cells during Cervical Cancer Progression [0.03%]
有关单细胞RNA测序分析的撤稿声明:刺猬信号通路在宫颈癌进展过程中促进上皮细胞的作用
Chen Ji,Yiyi Wang,Yingchun Jiang et al.
Chen Ji et al.
This article titled "Single-cell RNA-sequencing Analysis Reveals the Promoting Role of the Hedgehog Pathway in Epithelial Cells during Cervical Cancer Progression", published in Volume 32, Issue 33, 2025 of Current Medicinal Chemistry (10.2...
[18F]FDG PET/CT versus Bone Scintigraphy for the Diagnosis of Bone Metastasis in Breast Cancer: A Systematic Review and Meta-Analysis [0.03%]
乳腺癌骨转移诊断的18F-FDG PET/CT与骨扫描系统的meta分析研究
Xinmin Wang,Yufei Xu,Jing Jing
Xinmin Wang
Introduction: Breast cancer has become the most commonly diagnosed cancer in women worldwide, with advanced cases often leading to bone metastases that significantly affect prognosis and quality of life. This meta-analysi...
Cancer Stem Cell-targeted Antibody-drug Conjugates for Cancer Immunotherapy [0.03%]
靶向癌症干细胞的抗体-药物偶联物在癌症免疫治疗中的作用
Gyas Khan,Ali Hanbashi,Wedad Mawkili et al.
Gyas Khan et al.
Cancer stem cells (CSCs) participate in cancer initiation, metastasis, and therapy tolerance, presenting a formidable challenge in cancer treatment. Antibody-drug conjugates (ADCs) have been established as a potential strategy for selective...