Antimicrobial Activity of a Defensin-Rich Fraction from Capsicum Chinense Fruits: Insights for Biotechnological Applications against Fungal Infections [0.03%]
辣椒抗菌活性及富集防御肽的筛选与鉴定
Mariana C L Aguieiras,Érica O Mello,Larissa M Resende et al.
Mariana C L Aguieiras et al.
Background: The increasing resistance of fungal pathogens to conventional antifungal treatments has led to a global rise in fungal infections, affecting human health (Candida spp.) and agricultural productivity (Colletotr...
Purification, Crystallization, and Preliminary X-Ray Diffraction Studies on Hemoglobin from the Angora Goat (Capra Aegagrus Hircus) [0.03%]
山 goats（Capra aegagrus hircus）血红蛋白的纯化、结晶及初步 x 射线衍射研究
Farheen Pervez,Shobana Nagaraj,Mpho Setshedi et al.
Farheen Pervez et al.
Introduction: Angora goats are a distinct breed that differs significantly from common goats and shares a similar appearance to sheep. In Angora goats, only the level of glutathione (GSH) is elevated during under-stimulat...
Innovative Immunoinformatics Tools for Enhancing MHC (Major Histocompatibility Complex) Class I Epitope Prediction in Immunoproteomics [0.03%]
免疫蛋白质组学中增强MHC(I类 epitope预测的创新免疫信息学工具
Virendra S Gomase,Rupali Sharma,Suchita P Dhamane
Virendra S Gomase
Immune responses depend on the identification and prediction of peptides that bind to MHC (major histocompatibility complex) class I molecules, especially when it comes to the creation of vaccines, cancer immunotherapy, and autoimmune disor...
Protein and Peptide Therapeutics: Stability Challenges, Regulatory Demands, and Innovative Formulation Solutions for Enhanced Clinical Effectiveness [0.03%]
蛋白质和肽药物的稳定性挑战、监管要求及创新给药方式以提升临床疗效
Megha Patel,Dhruv Parikh,Akshay Parihar et al.
Megha Patel et al.
Proteins and peptides play a crucial role in biological functions and contemporary therapeutic approaches; however, their clinical effectiveness is frequently hindered by swift renal clearance and enzymatic degradation. Peptides possess str...
Optimizing Sleep in Athletes: The Potential of α-Lactalbumin in Nutrition Intervention [0.03%]
运动员睡眠优化：营养干预中α-乳清蛋白的潜力
Jingjing Li,Xuepeng Bian
Jingjing Li
Athletes frequently encounter sleep deprivation due to the demands of high-intensity training and competition, which can significantly impair their physical recovery and athletic performance. α-Lactalbumin (α-LA), a key component of whey ...
Serum and Urinary Proteomic Signatures Revealing Redox and Metabolic Dysregulation in Acute Achilles Tendon Rupture [0.03%]
急性跟腱断裂血清和尿液蛋白质组特征显示氧化应激及代谢紊乱迹象
Bayixiati Qianman,Tuomilisi Jiasharete,Aikeremu Wupuer et al.
Bayixiati Qianman et al.
Objectives: The etiology of acute Achilles tendon rupture (ATR) remains elusive. A comprehensive case-control study of the proteome profile was conducted to gain insights into the potential pathogenesis of acute ATR and i...
Engineered Bacteriophages: Advances in Phage Genome Redesign Strategies for Therapeutic and Environmental Applications [0.03%]
工程噬菌体：治疗和环境应用的噬菌体基因组重新设计策略的发展
Marzieh Rezaei,Amir Jalali,Dheyaa Hussein Sadah Al-Azzawi
Marzieh Rezaei
Bacteriophages, or phages, have emerged as powerful platforms in synthetic biology, offering innovative solutions for therapeutic and environmental challenges through advanced genome redesign strategies. This review explores a wide range of...
The Interaction between miRNAs and 14-3-3ζ Protein in Different Diseases [0.03%]
miRNA与14-3-3ζ蛋白在不同疾病中的相互作用
Ahmad Fazilat,Alireza Soleimani Mamalo,Salomeh Roshani et al.
Ahmad Fazilat et al.
Members of the 14-3-3 protein family are involved in various cellular processes, including migration, angiogenesis, cell cycle, apoptosis, and signal transduction. Nevertheless, the 14-3-3 family possibly plays a fundamental role in the dev...
Recombinant Expression of L-methioninase from Brevibacterium linens and Evaluation of its Anticarcinogenic Properties against MiaPaCa-2 Cells [0.03%]
来源于短乳杆菌的L-甲硫氨酶的重组表达及对MiaPaCa-2细胞抗癌性能的评估
Semih Latif İpek,Meryem Damla Özdemir Alkış,Ahmet Tülek et al.
Semih Latif İpek et al.
Introduction: This study aimed to investigate the anti-carcinogenic effects of recombinant L- methioninase (rBlmet) on the pancreatic cancer cell line MiaPaCa-2. ...
Effect of Adipokinetic Hormone on Learning-Memory in a Scopolamine-Induced Alzheimer's Model in Mice [0.03%]
adipokinetic激素对阿尔兹海默模型小鼠学习记忆的影响
Emre Uyar,Sibel Kokturk,Mohammed Omer Khalid Mohammed et al.
Emre Uyar et al.
Background: Neurosecretory cells of insects synthesize Adipokinetic Hormone (AKH). Previous studies indicated that AKH improves memory functions. Objectiv...