Remi-Martin Laberge,Pierre Awad,Judith Campisi et al.
Remi-Martin Laberge et al.
Depending on the cell type and tissue environment, epithelial and mesenchymal cell phenotypes are not static and can be highly dynamic. Epithelial-mesenchymal transitions (EMTs) and reverse EMTs provide flexibility during embryogenesis. Whi...
Sytse J Piersma
Sytse J Piersma
Cervical cancer is caused by Human papillomavirus (HPV) in virtually all cases. These HPV-induced cancers express the viral oncogenes E6 and E7 and are therefore potentially recognized by the immune system. Despite the abundant presence of ...
The interrelating dynamics of hypoxic tumor microenvironments and cancer cell phenotypes in cancer metastasis [0.03%]
缺氧肿瘤微环境与癌细胞表型在癌症转移中的相互作用动力学关系研究
Kai Bartkowiak,Sabine Riethdorf,Klaus Pantel
Kai Bartkowiak
The interrelating dynamics of the primary tumor cells and their surrounding microenvironment might determine phenotypic characteristics of disseminated tumor cells and contribute to cancer metastasis. Cytoprotective mechanisms (e.g., energy...
Vanessa Deschoolmeester,Marc Baay,Filip Lardon et al.
Vanessa Deschoolmeester et al.
There is growing evidence that both local and systemic inflammatory responses play an important role in the progression of a variety of solid tumors. Colorectal cancer (CRC) results from the cumulative effect of sequential genetic alteratio...
Alka Bhatia,Yashwant Kumar
Alka Bhatia
Cancer-immune (CI) equilibrium constitutes an important component of the cancer immunoediting theory. It is defined as a period during which our immune system and cancer live in harmony in the body. The immune system, though not able to com...
Differential Inductive Signaling of CD90 Prostate Cancer-Associated Fibroblasts Compared to Normal Tissue Stromal Mesenchyme Cells [0.03%]
与正常组织间质瘤细胞相比，CD90前列腺癌相关成纤维细胞的差异感应信号
Laura E Pascal,Junkui Ai,Ricardo Z N Vêncio et al.
Laura E Pascal et al.
Prostate carcinomas are surrounded by a layer of stromal fibroblastic cells that are characterized by increased expression of CD90. These CD90(+) cancer-associated stromal fibroblastic cells differ in gene expression from their normal count...
Lumican reduces tumor growth via induction of fas-mediated endothelial cell apoptosis [0.03%]
胶原蛋白结合蛋白lumican通过诱导Fas介导的内皮细胞凋亡抑制肿瘤生长
Kent E Williams,Logan A Fulford,Allan R Albig
Kent E Williams
Matrikines are important components of tumor microenvironments that integrate communication between extracellular matricies and membrane-bound receptors thereby regulating cellular behaviors. One such matrikine that is differentially expres...
The Potential Role of MT and Vimentin Immunoreactivity in the Remodeling of the Microenvironment of Parotid Adenocarcinoma [0.03%]
唾液腺癌微环境重塑中蛋白基因布BODY和波形蛋白的作用研究
Magdalena Dutsch-Wicherek,Agata Lazar,Romana Tomaszewska
Magdalena Dutsch-Wicherek
A tumor stimulates the remodeling of its microenvironment in order to control and accelerate its own growth and to initiate metastases. To create metastases the tumor cells must first acquire the ability to detach from the main tumor and to...
Effect of increased extracellular ca on microvesicle production and tumor spheroid formation [0.03%]
增加胞外钙对微囊生成及肿瘤细胞球形成的影响研究
Sarah Crawford,Deanna Diamond,Laura Brustolon et al.
Sarah Crawford et al.
Research on the composition of the tumor micro-environment has demonstrated that membrane delimited microvesicles are shed from many types of malignant tumors, in the peripheral blood of cancer patients as well as in culture media of tumor ...
Proteomic analysis of differentially expressed proteins in peripheral cholangiocarcinoma [0.03%]
外周型胆管癌差异表达蛋白的蛋白质组分析
Ian A Darby,Karine Vuillier-Devillers,Emilie Pinault et al.
Ian A Darby et al.
Cholangiocarcinoma is an adenocarcinoma of the liver which has increased in incidence over the last thirty years to reach similar levels to other liver cancers. Diagnosis of this disease is usually late and prognosis is poor, therefore it i...