Bioactive phytochemicals from Angelica glauca Edgew: a step toward novel therapeutics for respiratory tract infections [0.03%]
欧亚当药植物化学成分抗呼吸系统感染活性研究进展及展望新的药物治疗呼吸道感染
Prasant Arya,Rajendra Singh,Pankaj Kumar et al.
Prasant Arya et al.
Due to their vast chemical diversity, natural products derived from medicinal plants, whether as standardized extracts or isolated compounds, hold significant promise for new drug discovery. This study focused on the application of various ...
Akram N Salah,Youssef A Doghish,Shaimaa O Abbass et al.
Akram N Salah et al.
The human oral microbiome is a complex, dynamic ecosystem critically involved in maintaining oral health and contributing to systemic well-being. Many bacteria and fungi are involved in oral cavities such as Penicillium, Rhodotorula, Saccha...
Pink powerhouses: insights into the multifaceted role of Methylobacterium in climate-resilient farming [0.03%]
粉红力量——气候适应型农业中多功能甲基单胞菌的多重角色初探
Pragadeesh Ayyamuthu Rajarathinam Uma,Parimala Devi Rathinasamy,Ramesh Thanakkan et al.
Pragadeesh Ayyamuthu Rajarathinam Uma et al.
The plant microbiomes consist of a myriad of microorganisms that inhabit and interact with plant tissues and play pivotal roles in improving crop productivity and sustainability. These microbiomes constitute bacteria, fungi, archaea and vir...
Evaluation of the interaction and synergy potential of bedaquiline and clarithromycin in combination with efflux pump inhibitors in clinical isolates of Mycobacterium abscessus complex [0.03%]
评估贝达喹啉和克拉霉素联合外排泵抑制剂对分枝杆菌鸟分枝杆菌复合体临床分离株的相互作用及协同潜力
Esra Gül Tursun,Taylan Bozok,Can Biçmen et al.
Esra Gül Tursun et al.
Nontuberculous mycobacteria (NTM) cause difficult-to-treat pulmonary infections due to their high antimicrobial resistance. Among them, the Mycobacterium abscessus complex (MABC) is a major pathogen characterized by prolonged treatment cour...
Emerging contaminants in healthcare effluents: antibiotic resistance and virulence factor dissemination [0.03%]
医疗废水中的新污染物:抗生素抗性及毒力因子的传播
Jaya Malik,Zayera Naushad,Shilpy Singh et al.
Jaya Malik et al.
Antibiotic-resistant microorganisms are a major concern for researchers, medical experts, and public healthcare workers. Healthcare organizations, particularly wastewater from hospitals, can pose a significant global health risk if wastewat...
Rta1 lipid transporter involved in aluminum and acid tolerance in Cryptococcus humicola [0.03%]
Cryptococcus humicola中的Rta1脂质转运蛋白可参与铝和酸胁迫耐受性
Yong Li,Yanjie Mao,Yongjie Wu et al.
Yong Li et al.
Aluminum (Al) toxicity is a major limiting factor for crop growth in acidic soils worldwide. Therefore, it is necessary to study Al-tolerance mechanisms. Cryptococcus humicola is a good candidate for Al-tolerance research due to its high ab...
Antioxidant and cytotoxic activities of extracts from rare saprobic fungi, Melanographium smilacis, Helminthosporium chiangraiense, Pleopunctum thailandicum, and Pseudochaetosphaeronema chiangraiense [0.03%]
稀有腐生真菌Melanographium smilacis,Helminthosporium chiangraiense,Pleopunctum thailandicum和Pseudochaetosphaeronema chiangraiense提取物的抗氧化和细胞毒性作用
Sarunpron Khruengsai,Teerapong Sripahco,Prasat Kittakoop et al.
Sarunpron Khruengsai et al.
Saprobic fungi remain underexplored sources of bioactive secondary metabolites with pharmaceutical potential. This study presents the first biological evaluation of four rarely studied species, Melanographium smilacis, Helminthosporium chia...
Isolation, identification, and bioactivity evaluation of endophytic fungi from Ruta graveolens: insights into antimicrobial and antioxidant potential [0.03%]
牻牛儿苗内生真菌的分离鉴定及活性筛选研究
Qianyun Hao,Wei Wang,Yanlin He et al.
Qianyun Hao et al.
This study presents a comprehensive investigation of endophytic fungi isolated from Ruta graveolens (Rutaceae), evaluating the bioactivity of their extracts in terms of antimicrobial and antioxidant properties, along with preliminary mycoch...
Pseudomonas spp. and antimicrobial resistance: unlocking new horizons with 1-hydroxyphenazine [0.03%]
不动杆菌和抗菌药物耐药性:利用1-羟基菲嗪开拓新视野
Khaled Abuelhaded,Hend H Mohamed,Ahmed Hassan Ibrahim Faraag et al.
Khaled Abuelhaded et al.
Antimicrobial resistance (AMR) is a mounting global health challenge projected to cause up to 10 million deaths annually by 2050. Despite advances in antibiotic discovery, the rapid emergence of multidrug-resistant (MDR) and extensively dru...
Anticancer compounds from Streptomyces: insights from metagenomics and mechanistic perspective [0.03%]
链霉菌的抗肿瘤化合物:元基因组学和作用机制分析的新视角
Muhanna Mohammed Al-Shaibani,Noraziah Mohamad Zin,Juwairiah Remali et al.
Muhanna Mohammed Al-Shaibani et al.
Cancer continues to be a leading cause of death globally, driving the ongoing search for novel bioactive compounds with therapeutic potential. Metagenomic sequencing has revolutionized this pursuit by enabling the direct detection and genom...