Bioactive compounds isolated from the bark of Aesculus glabra Willd [0.03%]
Aesculus glabra威氏种树皮中分离得到的活性成分研究
Miriam Velazquez Cruz,Eric Salinas-Arellano,Ines Castro Dionicio et al.
Miriam Velazquez Cruz et al.
The Aesculus genus has several species, most notably Aesculus hippocastanum, with reported cytotoxic and venotonic effects. The angiogenic effect from A. hippocastanum is of interest given the current limitations of anti-angiogenic therapeu...
Charmaine A Lindsay,Choon Y Tan,Deepa Krishnan et al.
Charmaine A Lindsay et al.
Lichens are symbiotic organisms comprised of mycobionts and photobiont partners. They are known to produce bioactive secondary metabolites and most of these are biosynthesized by mycobionts. Investigations of cultures of isolated lichen-ass...
What was old is new again: Phenotypic screening of a unique fungal library yields pyridoxatin, a promising lead against extensively resistant Acinetobacter baumannii (AB5075) [0.03%]
以菌治药，老法新用——筛选独特真菌文库获得抗击耐药细菌先导化合物吡啶可汀
Heather L Winter,Laura Flores-Bocanegra,Kristóf B Cank et al.
Heather L Winter et al.
Due to the emergence of resistance, the World Health Organization considers Gram-negative pathogen Acinetobacter baumannii a top priority for therapeutic development. Using this priority pathogen and a phenotypic, agar plate-based assay, a ...
Synthesis and evaluation of diterpenic Mannich bases as antiviral agents against influenza A and SARS-CoV-2 [0.03%]
合成和评估作为对抗流感A和SARS-CoV-2的抗病毒剂的二萜曼尼希碱的研究
Elena V Tret&#x;yakova,Xinyuan Ma,Oxana B Kazakova et al.
Elena V Tret&#x;yakova et al.
A chemical library was constructed based on the resin acids (abietic, dehydroabietic, and 12-formylabietic) and its diene adducts (maleopimaric and quinopimaric acid derivatives). The one-pot three-component CuCl-catalyzed aminomethylation ...
Isolation and elucidation of two isoflavonoids from an American Indian plant, Amorpha canescens Pursh, using Magnetic Microbead Affinity Selection Screening (MagMASS) for estrogen receptor alpha ligands [0.03%]
利用磁性微球亲和选择筛选（MagMASS）从美洲土木草中分离并鉴定两种异黄酮化合物为雌激素受体α配体
Tristesse C J Burton,David C Lankin,Dejan Nikolic et al.
Tristesse C J Burton et al.
A new isoflavonoid, xanthocerin J, along with previously described xanthocerin A, were isolated from a methanol extract of aerial parts of a traditional American Indian herb, Amorpha canescens Pursh (Asteraceae). The structures of these com...
Spermidine alkaloid and glycosidic constituents of Vietnamese Homalium cochinchinensis [0.03%]
越南产Homalium cochinchinensis的聚胺生物碱和糖苷类成分
Ermias Mekuria Addo,Yulin Ren,Gerardo D Anaya-Eugenio et al.
Ermias Mekuria Addo et al.
Phytochemical investigation of the aerial parts of Homalium cochinchinensis led to the isolation of secondary metabolites belonging to the spermidine alkaloid, glycoside, depsidone and phenol classes. Of the eleven secondary metabolites iso...
Structure Characterization and Biological Activity of 2-Arylbenzofurans from an Indonesian Plant, Sesbania grandiflora (L.) Pers [0.03%]
来自印度尼西亚植物苏木(Sesbania grandiflora (L.) Pers)的2-芳基苯并呋喃的结构表征及其生物活性研究
Noviany Noviany,Arash Samadi,Nita Yuliyan et al.
Noviany Noviany et al.
A new 2-arylbenzofuran, sesbagrandiflorain C (1), together with four known compounds, 2-(3,4-dihydroxy-2-methoxyphenyl)-4-hydroxy-6-methoxybenzofuran-3-carbaldehyde (2), 2-(4-hydroxy-2-methoxyphenyl)-5,6-dimethoxybenzofuran-3-carboxaldehyde...
Clarice Noleto-Dias,Claudia Harflett,Michael H Beale et al.
Clarice Noleto-Dias et al.
Phytochemical profiling of a hybrid species of willow, Salix × alberti L. (S. integra Thunb. × Salix suchowensis W.C. Cheng ex G.Zhu) revealed four sulfated flavonoids, which were then isolated from young stem tissue. The structures of di...
Using MS-FINDER for identifying 19 natural products in the CASMI 2016 contest [0.03%]
MS-FINDER在CASMI 2016挑战赛中识别19个天然产物方面的应用
Arpana Vaniya,Stephanie N Samra,Mine Palazoglu et al.
Arpana Vaniya et al.
In its fourth year, the CASMI 2016 contest was organized to evaluate current chemical structure identification strategies for 19 natural products using high-resolution LC-MS and LC-MS/MS challenge datasets using automated methods with or wi...