1H, 13C, and 15N backbone resonance assignments of the A2 domain of human von Willebrand factor [0.03%]
人血管性假血友病因子A2结构域的氢-1(1H),碳-13(13C)和氮-15(15N)主链共振分配
Ryuichi Hyakumoto,Masatomo So,Ayako Furukawa et al.
Ryuichi Hyakumoto et al.
The A2 domain of von Willebrand factor (vWF A2) acts as a mechanosensor, unfolding under shear stress to enable cleavage by ADAMTS13. Dysfunction of this process causes von Willebrand disease (VWD) and thrombotic thrombocytopenic purpura (T...
Amide 1H and 15N NMR signal assignments of all naturally-occurring di-ubiquitins [0.03%]
所有天然存在的二泛素的酰胺1H和15N核磁共振信号指派
Iladeiti Kurbah,Carlos A Castañeda,David Fushman
Iladeiti Kurbah
Ubiquitin acts as a building block for a wide variety of poly-ubiquitin chains. Decoding the role of poly-ubiquitin chains in different cellular processes remains an active area of research. Here, we report amide 1H and 15N signal assignmen...
1H, 13C and 15N resonance assignments for human all-Ala α-lactalbumin in its molten globule and urea-denatured states [0.03%]
人全Alaα-乳碱素在熔融球状体和尿素变性态中的氢-1H, 碳-13C和氮-15N共振指派
Lorena Varela,Lorna J Smith,Christina Redfield
Lorena Varela
Molten globules are compact, partially-folded proteins postulated to be general intermediates in protein folding. Human α-lactalbumin (α-LA) is a Ca2+-binding, four-disulphide protein whose native structure is divided into two lobes, one ...
Backbone resonance assignment of the pentraxin domain of the neuronal pentraxin receptor (NPTXR) [0.03%]
神经元五聚蛋白受体(NPTXR)的五聚蛋白结构域的骨架共振分配
Alexandra K Pozhidaeva,Yunfeng Li,Yulia Pustovalova et al.
Alexandra K Pozhidaeva et al.
Neuronal pentraxin receptor (NPTXR) is a synaptic organizing protein important for excitatory neurotransmission, yet its structural properties remain poorly defined. The conserved C-terminal pentraxin (PTX) domain of NPTXR (NPTXRPTX) is exp...
1HN, 13C, and 15N resonance assignments of Ca2+-calmodulin bound to a BP2 peptide derived from the sheep STRA6 vitamin A transporter (residues 625-656) [0.03%]
钙离子-钙调蛋白与羊STRA6视黄醛转运多肽BP2结合复合物(第625-656位残基)的氢-1,碳-13和氮-15共振峰鉴定
Mary E Cook,Kristen M Varney,Xinhao Zhuang et al.
Mary E Cook et al.
Vitamin A is essential for vision and many other biological processes required for human health and survival. Extracellular retinol binding protein (RBP) delivers vitamin A into the cell upon binding to the vitamin A transporter, STRA6. How...
Backbone NMR resonance assignments for the C2 domain of the Streptococcus mutans adhesin P1 [0.03%]
变异链球菌黏附素P1的C2结构域的主骨架NMR共振指派
Emily-Qingqing Peng,M Luiza Caldas Nogueira,Chase Norton et al.
Emily-Qingqing Peng et al.
Adhesin P1 (aka AgI/II) is an extracellular protein regulating adherence and detachment of Streptococcus mutans in the oral cavity and thus plays a pivotal role in biofilm development and maturation. P1's naturally occurring C-terminal trun...
1H, 13C, and 15N resonance assignments and solution structure of the CID domain of SR-related- and CTD-associated factor 8 (SCAF8) [0.03%]
SR相关和CTD相关因子8(SCAF8)的CID结构域的1H,13C和15N共振分配及溶液结构
Weirong Dang,Yutaka Muto,Fahu He et al.
Weirong Dang et al.
Transcription mediated by RNA polymerase II (RNAPII) involves multiple stages, including initiation, promoter-proximal pausing for capping, elongation, and termination. The C-terminal domain of RNAPII (CTD) contains repetitions of the hepta...
NMR assignments of the human homodimeric mitochondrial ATP synthase inhibitor IF1 [0.03%]
人源线粒体ATP合酶抑制因子IF1的同二聚体的核磁共振解析
Julia Jerolamon,Nathan N Alder,Andrei T Alexandrescu
Julia Jerolamon
ATPase inhibitory factor 1 (IF1) is the only known endogenous, proteinaceous inhibitor of mitochondrial ATP synthase in mammals. The inhibitor forms an antiparallel coiled-coil, which binds ATP synthase through an N-terminal α-helix extens...
1H, 13C and 15N backbone resonance assignment of the lytic polysaccharide monooxygenase LsAA9A from Lentinus similis [0.03%]
来自Lentinus similis的lytic多糖单加氧酶LsAA9A的氢-1,碳-13和氮-15主链共振指派
Piera Wiesinger,Mats Sandgren,Gustav Nestor
Piera Wiesinger
Lytic polysaccharide monooxygenases (LPMOs) are mono-copper binding enzymes involved in the degradation of carbohydrates. The 25 kDa sized LPMO LsAA9A from the basidiomycete Lentinus similis is known to oxidate cellulose and cellooligomers ...
Sequential backbone chemical shift assignments of a cancer-associated isoform of the HBx protein from human hepatitis B virus [0.03%]
人肝炎B病毒癌症相关异构体HBx蛋白的连续背骨化学位移指派
Alexis Clavier,Toshinobu Shida,Maxim A Droemer et al.
Alexis Clavier et al.
Chronic infections with hepatitis B virus (HBV) are a leading cause of liver cirrhosis and hepatocellular carcinoma worldwide. Among the four viral proteins encoded by HBV, the X protein (HBx) has remained resistant to atomic-level characte...