NMR assignments of the human homodimeric mitochondrial ATP synthase inhibitor IF1 [0.03%]
人源线粒体ATP合酶抑制因子IF1的同二聚体的核磁共振解析
Julia Jerolamon,Nathan N Alder,Andrei T Alexandrescu
Julia Jerolamon
ATPase inhibitory factor 1 (IF1) is the only known endogenous, proteinaceous inhibitor of mitochondrial ATP synthase in mammals. The inhibitor forms an antiparallel coiled-coil, which binds ATP synthase through an N-terminal α-helix extens...
1H, 13C and 15N backbone resonance assignment of the lytic polysaccharide monooxygenase LsAA9A from Lentinus similis [0.03%]
来自Lentinus similis的lytic多糖单加氧酶LsAA9A的氢-1，碳-13和氮-15主链共振指派
Piera Wiesinger,Mats Sandgren,Gustav Nestor
Piera Wiesinger
Lytic polysaccharide monooxygenases (LPMOs) are mono-copper binding enzymes involved in the degradation of carbohydrates. The 25 kDa sized LPMO LsAA9A from the basidiomycete Lentinus similis is known to oxidate cellulose and cellooligomers ...
Sequential backbone chemical shift assignments of a cancer-associated isoform of the HBx protein from human hepatitis B virus [0.03%]
人肝炎B病毒癌症相关异构体HBx蛋白的连续背骨化学位移指派
Alexis Clavier,Toshinobu Shida,Maxim A Droemer et al.
Alexis Clavier et al.
Chronic infections with hepatitis B virus (HBV) are a leading cause of liver cirrhosis and hepatocellular carcinoma worldwide. Among the four viral proteins encoded by HBV, the X protein (HBx) has remained resistant to atomic-level characte...
1H, 13C, and 15N resonance assignment of the C terminal region of the disordered postsynaptic scaffold protein GKAP [0.03%]
GKAPpostsynaptic蛋白支架蛋白无序区C末端的氢-1（1H），碳-13（13C）和氮-15（15N）共振指认
Eszter Nagy-Kanta,Anna Sánta,Zsófia E Kálmán et al.
Eszter Nagy-Kanta et al.
Guanylate kinase-associated protein, GKAP, is a largely disordered scaffold protein with multiple interaction partners, playing a role in the organization of the postsynaptic protein network. Its C-terminus contains a binding motif for the ...
Jelena Grga,Emmanuelle Boll,Guy Lippens et al.
Jelena Grga et al.
LCCICCG, a bioengineered variant of a cutinase called LCC (Leaf-branch Compost Cutinase), is a high-performance, industrial-grade enzyme capable of efficiently degrading polyethylene terephthalate (PET). This engineered enzyme exhibits sign...
1H, 13C, and 15N backbone resonance assignments of full-length and a SIM-SEP-containing fragment (101-266) of p47, a p97 adaptor protein [0.03%]
全长和含SIM-SEP片段（101-266）的p47的氢-13碳-15氮主链共振分配（p97适配蛋白）
Rajivan Raseekan,Megan K Black,Rui Huang
Rajivan Raseekan
p47/NSFL1C is a key adaptor protein of p97/VCP, a AAA+ ATPase that is involved in a diverse array of cellular functions. p47 directs p97 activity towards membrane remodelling and contributes to the regulation of cellular pathways such as NF...
Resonance assignments of the human receptor interacting protein kinase 1 (RIPK1) in its fibrillar conformation [0.03%]
人交互作用蛋白激酶1（RIPK1）原纤维构象的共振赋值
Paula Polonio,Miguel Mompeán
Paula Polonio
Receptor-interacting protein kinase 1 (RIPK1) is a key regulator of necroptotic signalling that forms functional amyloid fibrils through its RIP Homotypic Interaction Motif (RHIM). Here, we report the solid-state NMR chemical shift assignme...
1H, 13C and 15N backbone resonance assignment of the RNA binding motif 39 (RBM39) tandem RNA recognition motifs (RRM1-2) [0.03%]
RBM39 蛋白 RRMs 1-2 域的氮氢原子核磁共振谱的完全分配
Florian Malard,Léa Bouton,Sébastien Campagne
Florian Malard
The N-terminal tandem RNA Recognition Motifs (RRM1-2) of the splicing factor RNA Binding Motif 39 (RBM39) from Homo sapiens was expressed in E. coli with 13C and 15N labeling. A nearly complete assignment of backbone 1H, 15N, and 13C resona...
Abigail Page,Wyatt Hendricks,Marielle A Wälti
Abigail Page
The human chaperonin system, Hsp60/Hsp10, is essential for maintaining protein homeostasis and is found mainly in mitochondria. Hsp60 forms a bowl-shaped structure that provides an enclosed environment for protein folding, while its co-chap...
Resonance assignments of asymmetric tetrameric platelet factor 4 (PF4) [0.03%]
不对称四聚体血小板因子4(PF4)的共振赋值
Qiulin Ma,Jinfeng Huang,Stephen Boulton et al.
Qiulin Ma et al.
Platelet Factor 4 (PF4), also known as CXCL4, is a CXC chemokine crucial for hemostasis, inflammation, and immune responses. Under physiological conditions PF4 assembles into asymmetric tetramers (31.2 kDa) that are dimers of dimers with hi...